Streptomyces spinosirectus: LXH13_37960
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Entry
LXH13_37960 CDS
T08958
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
sspn
Streptomyces spinosirectus
Pathway
sspn00280
Valine, leucine and isoleucine degradation
sspn00640
Propanoate metabolism
sspn00785
Lipoic acid metabolism
sspn01100
Metabolic pathways
sspn01110
Biosynthesis of secondary metabolites
sspn01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sspn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
LXH13_37960
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
LXH13_37960
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
LXH13_37960
Enzymes [BR:
sspn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
LXH13_37960
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Gene cluster
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
UIR22474
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Position
8292993..8295179
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AA seq
728 aa
AA seq
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MPAEHSLEANAVWSEFVVTKDDWDAADPDLLTGMFSQLVLIRTFEEYVLELAADGLIHGP
AHSSIGQEGGAVGACYSLTSEDTVNGSHRGHHQFLAKVLAHLHPKGIDPRKPFPEDVRTA
LLRSLREICGLDQGFSHGRGGSMHLQWHEAGAIGTNAIVGGGVPLAAGSAWAHKAAGTRA
ATFTFFGDGAINIGSTLETLNLAAAWSLPLCFFVENNLYAVSTHVSEVTAEPRLSGRGPG
FGIRSWKVDGMDPLAVYMVTQEALAHMRSGKGPTMIEADVYRYFHQNGPFPGSAFRYRTK
EEEAQWRSRDPIDTVAGHLTRRRILSEKAVSETLARAKALMADLGDVLLEPRPGGKQGER
RIVPSEWPDPAFVDEGIRGDLSELAAIEFTDAEDFADELTEVKFIGAVADVMKRRLETDP
RVLVMGEDVHRLNGGTNGATRGLSDAFPDRVLGTPISENAFAGLGGGLAMDGRFRPIVEF
MYADFMWVAADQLFNQIGKARHMFGGEGKVPFVLRSKVATGTGYGSQHSMDPAGIFATAP
GWRIVAPSTPFDYVGLMNTALACDDPVVVLEHVDLYNSTGPGLPENYDHCLPVGKAAVRR
EGAALTIITYLAMTPAVLDAVEQTGVDAEVIDLRWLDRASLDWETVTRSVMKTNNVLIAE
QGAIGTSYGGWLADEIQRRLFDWLDAPIERVTGGEASPSISKILERAAYASTEEVVAKLR
DMQEQSNG
NT seq
2187 nt
NT seq
+upstream
nt +downstream
nt
atgcctgcggaacactcactcgaagcgaacgccgtgtggtcggagttcgtcgtcaccaag
gacgactgggacgccgcggacccggacctgttgacgggcatgttcagccagctcgtcctc
atccgcaccttcgaggagtacgtccttgagctggccgcggacggactcatccacggcccc
gcgcactccagcatcggtcaggaaggcggggccgtcggtgcctgctattccctgacgtcc
gaggacaccgtcaacggttcacatcgaggccatcaccagttcctcgccaaggtgctcgcc
catcttcatccgaagggcatcgaccccagaaagccgttccccgaggatgtacggaccgca
ctcctgcgcagcctgcgcgagatctgcggactggaccagggcttcagccatgggcgagga
ggcagcatgcacctccagtggcacgaggccggcgccatcggcaccaacgccatcgtcggc
ggtggcgtaccgctcgcggccggatccgcatgggcccacaaggcggccggcacccgggcg
gcgaccttcacgttcttcggcgacggtgcgatcaacatcggatccacgctggagaccctc
aatctcgcggcggcctggtcgctgcccctgtgcttcttcgtcgagaacaacctgtacgcc
gtctccacccacgtgtccgaagtcaccgccgaaccacggttgtcgggccggggcccgggc
ttcggcatccggagctggaaggtcgacggcatggatccgctggccgtctacatggtgacg
caggaagcactcgcccacatgcggagcggcaagggcccgaccatgatcgaggccgatgtg
taccgctacttccaccagaacggccccttccccggctcggcgtttcgctatcgcaccaag
gaagaagaagcgcaatggcgctctcgcgacccgatcgacaccgtcgcgggccatctgaca
cgccgtcgaatcctcagtgagaaggcggtctcggagacgctcgcgcgagccaaggccctg
atggccgacctcggcgacgttctcctggagccacggccgggcggcaagcagggagaacgg
cgcatcgtcccctccgagtggcccgatccggccttcgtcgacgaaggcatccggggcgac
ctgtcggaactcgccgcgatcgagttcaccgacgcggaggacttcgccgacgaactgacc
gaggtcaagttcatcggcgccgtcgccgacgtgatgaagcgccgcctggagaccgatccc
cgtgtcctggtgatgggcgaggacgtgcaccggctcaacggcggtaccaacggtgccacc
cgcggtctgagcgatgcgttccccgaccgtgtgctcggtacgccgatctcggagaacgcg
ttcgcaggcctgggcgggggactggccatggacggccggttccggccgatcgtcgagttc
atgtacgcggacttcatgtgggtggcggcggaccagctcttcaaccagatcggcaaggcg
cgccacatgttcggcggcgagggcaaggtgccgttcgtcctgcgcagcaaggtcgccacc
ggcaccggttacggatcgcagcactcgatggaccccgccggcatcttcgcgacggcaccc
ggctggcggatcgtggccccgtccacgccgttcgactacgtcggcctgatgaacacggca
ctggcgtgtgacgacccggtcgtcgttctggagcacgtggacctgtacaactccacaggt
ccgggtctgccggagaactacgaccactgtctcccggtgggcaaggccgccgtacgtcgt
gagggagcggccctgaccatcatcacctacctggcgatgacaccggccgtcctcgacgct
gtcgagcagacgggtgtggacgccgaggtcatcgatctgcgctggctcgaccgggccagc
ctggactgggaaacagtcacccggtcggtgatgaagaccaacaatgtgctgatcgccgag
cagggcgccatcggcacctcctacggcggctggctcgccgatgagatccagcgccggctg
ttcgactggctcgacgccccgatcgagcgcgtgaccggcggtgaagcgtcgccgagcatc
agcaaaatcctcgaacgtgccgcgtacgcctccacggaggaagtcgtggccaaactccgt
gacatgcaggagcagagcaatggctga
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