Streptomyces spongiicola: DDQ41_03070
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Entry
DDQ41_03070 CDS
T06937
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sspo
Streptomyces spongiicola
Pathway
sspo00300
Lysine biosynthesis
sspo00550
Peptidoglycan biosynthesis
sspo01100
Metabolic pathways
sspo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sspo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
DDQ41_03070
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
DDQ41_03070
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
DDQ41_03070
Enzymes [BR:
sspo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
DDQ41_03070
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
AWK08089
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Position
complement(730460..731896)
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AA seq
478 aa
AA seq
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MISLSLAEIADIVGGRPHDIPDPSVRVTGPVVRDSREVVPGSLFVAFAGARVDGHDYAAD
VVAAGAAGVLASRPVGVPAVVVDDVPRALGALARAVVRRLGATLVALTGSAGKTSTKDLV
AQVLRREAPTVWTPGSLNNEIGLPLTALSATDETRFLVLEMGARGIGHIRYLTQLTPPRV
GVVLNVGSAHIGEFGGREQIAEAKGELVETLPPAEAGGVAVLNADDPLVRAMSARTKARV
VLFGESDEADVRAENVRLLPGGRPAFLLRTPSGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMSVDEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGAAAE
AAGGRTWAVLGPMAELGGEALAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSW
GEESVHVSDARAAVDLLRRELRPGDVVLVKASRSAGLERIAEALLADAGPAEGQVAGR
NT seq
1437 nt
NT seq
+upstream
nt +downstream
nt
gtgatcagcctctccctcgccgagatcgccgacatcgtgggcgggcggccgcacgacata
ccggatccgtccgtacgcgtcaccgggcccgtcgtccgcgactcgcgcgaggtcgtgccc
ggcagcctcttcgtcgccttcgccggcgcccgcgtcgacggccacgactacgccgcggac
gtggtcgccgcgggtgcggccggcgtgctggcctcgcggcccgtcggtgtgcccgccgtc
gtcgtggacgacgtcccgagggctctgggcgcgctggcccgtgccgtggtgcggcgcctg
ggcgccaccctggtggccctcaccggctccgcggggaagaccagcaccaaggacctcgtc
gcgcaggtgctgcgccgcgaggcgccgaccgtctggacccccggctcgctgaacaacgag
atcggcctgccgctgaccgcgctcagcgccaccgacgagaccaggttcctggtcctcgag
atgggcgcccgcggcatcggccacatccgctacctcacccagctcaccccgccccgcgtc
ggagtggtgctgaacgtgggcagcgcccacatcggcgagttcggcggccgcgagcagatc
gccgaggccaagggcgagctggtggagacgctgccccccgccgaagcgggcggggtggcc
gtcctcaacgccgacgaccccctcgtccgcgccatgtcggcccgcaccaaggcacgtgtc
gtgctgttcggggagtcggacgaagcggacgtacgcgccgagaacgtccgcctgctgccc
ggcggacggcccgcgttcctgcttcgcacaccctccgggtgcagcgacgtgaccttgcgg
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagctg
ggcatgtccgtcgacgagatcgccaccgcgctctcggaggccggcaccctctcccgctgg
cgtatggaggtcaccgagcgtccggacggcgtcacgatcgtcaatgacgcctacaacgcg
aaccccgagtccatgcgagccgcactgcgtgcgctcgccgccatgggcgcggccgccgag
gccgccggggggcgcacgtgggcggtgctcggtccgatggccgagctcggcggcgaggcg
ctggccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcgggggcagggaagcgtcctggctgcaactgggcgcctataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcgggcggcggtcgacctgttgcgcagagag
ctgcgcccgggagacgtcgtgctggtgaaggcttccaggtcggccgggctcgagcggatc
gccgaggcgctgctcgcagacgccggtccggccgaggggcaggtcgccggccgatga
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