Streptomyces spongiicola: DDQ41_16435
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Entry
DDQ41_16435 CDS
T06937
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
sspo
Streptomyces spongiicola
Pathway
sspo00280
Valine, leucine and isoleucine degradation
sspo00640
Propanoate metabolism
sspo00785
Lipoic acid metabolism
sspo01100
Metabolic pathways
sspo01110
Biosynthesis of secondary metabolites
sspo01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
sspo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DDQ41_16435 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DDQ41_16435 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DDQ41_16435 (pdhA)
Enzymes [BR:
sspo01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DDQ41_16435 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AWK10224
UniProt:
A0A2S1Z1G2
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All DBs
Position
3744801..3745991
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AA seq
396 aa
AA seq
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MTVENTAARKPRRSSKRVSAAKKPTSSEPQLVQLLTPEGERVANPDYDRHVADLGPEELR
GLYRDMVLTRRFDAEATALQRQGELGLWASLLGQEAAQIGSGRALRDDDYVFPTYREHGV
AWCRGVDPTNLLGMFRGVNHGGWDPGSNNFHLYTIVIGSQTLHATGYAMGVAKDGADSAV
IAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTERQTRVPLYQRAQGYGF
PGVRVDGNDVLACLAVTRSALERARRGEGPTLVEAFTYRMGAHTTSDDPTRYRHDDERAA
WEAKDPILRLRKYLADQGHADEAFFTGLEAESDTLAKRVREAVRAMPDPDDMAMFEHVYA
DGHALVDEERAQFAAYQASFSTEPDSGSAAGAEEGK
NT seq
1191 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagaacactgccgcgcgcaaaccgcgccgcagcagtaagcgcgtcagcgcc
gcgaagaagccaacgagttccgagccccagctcgtacagctgctgacgcccgagggcgag
cgggtggccaacccggactacgaccgccatgtcgccgacctcggccccgaggagcttcgc
gggctctaccgggacatggttctcacccgtcgtttcgacgccgaggccaccgccctccag
cgccagggcgagctgggcctgtgggcctcgctgctcggccaggaggccgcccagatcggc
tccggacgcgcactgcgcgacgacgactacgtcttcccgacctaccgcgagcacggggtc
gcctggtgccgcggagtcgacccgacgaacctgctgggaatgttccgcggcgtgaaccac
ggagggtgggaccccggcagcaacaacttccatctgtatacgatcgtcatcggctcgcag
acgctgcacgccaccgggtacgcgatgggggtcgccaaggacggcgcggactccgcggtg
atcgcgtacttcggcgacggcgcctccagtcagggcgacgtggcggagtcgttcaccttc
tccgcggtctacaacgccccggtcgtgttcttctgccagaacaaccagtgggcgatctcc
gagcccaccgagcgccagacccgggtaccgctctaccagcgagcccagggctacggcttc
cccggtgtccgcgtcgacggcaacgacgtgctcgcctgcctggccgtgacccggtcggcg
ctggagcgcgcccgccgcggggagggccccacgctggtcgaggcgttcacctaccgcatg
ggcgcccacaccacctcggacgacccgacccgctaccgccacgacgacgagcgggcggcc
tgggaggccaaggacccgatcctgaggctgcggaagtacctggccgaccagggccacgcc
gacgaggccttcttcaccgggctggaggcggagagcgacacgctcgccaagcgcgtccgc
gaggcggtgcgcgccatgcccgacccggacgacatggcgatgttcgagcacgtctacgcc
gacgggcacgcgctcgtcgacgaggagcgcgcgcagttcgccgcgtaccaggcgtcgttc
agcacggagccggacagcggctccgccgcgggtgccgaggagggcaagtag
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