Streptococcus salivarius CCHSS3: SALIVB_0604
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Entry
SALIVB_0604 CDS
T01580
Symbol
gshAB
Name
(GenBank) glutathione biosynthesis bifunctional protein gshAB (Gamma-GCS-GS) (GCS-GS) [Includes: Glutamate--cysteine ligase (EC 6.3.2.2) (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS); Glutathione synthetase (Glutathione synthase) (GSH synthetase) (GSH-S) (GSHase) (GS)]
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ssr
Streptococcus salivarius CCHSS3
Pathway
ssr00270
Cysteine and methionine metabolism
ssr00480
Glutathione metabolism
ssr01100
Metabolic pathways
ssr01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ssr00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
SALIVB_0604 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
SALIVB_0604 (gshAB)
Enzymes [BR:
ssr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
SALIVB_0604 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
ATP-grasp_3
GARS_A
Dala_Dala_lig_C
ATPgrasp_ST
ATP-grasp_4
R2K_3
Motif
Other DBs
NCBI-ProteinID:
CCB92907
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Position
complement(589714..591978)
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AA seq
754 aa
AA seq
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MTINQLLQKLEPTSPILQANFGIERESLRVDRQGKLAHTPHPSCLGARSFHPYIQTDFCE
FQMELITPVAKSTTEARRFLGAITDVAGRSISKDELLWPLSMPPRIKAQEIQVAQLENEF
ERHYRNYLAEKYGTKLQAISGIHYNMELGKDLVEALFKESNQTDMIAFKNALYLKLAQNY
LRYRWVITYLFGAAPVAEQGFFDQEVPEPVRSFRNSDHGYVNKEEIQVSFASLEDYVSAI
ENYIEQGDLIAEKEFYSAVRFRGQKVNRSFLDKGITYLEFRNFDLNPFERIGISQTTMDT
VHLLLLAFLWMDASENVDQSLAQGHVLNEKIALSHPLEPLPSETETQNITTALDQLVQHF
GLGDYHQDLVKQVKDAFADPSQTLAAQLLPHIKDKSLADFALDKALAYHDYDWTAHYALK
GYEEMELSTQMLLFDAIQKGIHFEILDEQDQFLKLWHKDHVEYVKNGNMTSKDNYVVPLA
MANKTVTKKILADAGFPVPAGDEFTSLEQGLAYYPLIKDKQIVVKPKSTNFGLGISIFQE
PASLDNYKKALEIAFAEDTAVLVEEFIPGTEYRFFILDGRCEAVLLRVAANVVGDGKHTI
RELVAQKNANPLRGRDHRSPLEIIELGDIEQLMLTQQGYTPDDILPEGKKVNLRRNSNIS
TGGDSIDVTETMDSSYQELAAAMATSMGAWACGVDLIIPDETQPASKENPHCTCIELNFN
PSMYMHTYCAEGPGQAITSKILDKLFPEVATNQN
NT seq
2265 nt
NT seq
+upstream
nt +downstream
nt
atgactataaatcaactgcttcaaaagctggagcctaccagccctatccttcaagctaac
tttggaattgaacgcgaaagtcttcgtgtcgatagacagggaaaattagcacatacgcct
cacccttcctgcctaggagctcgaagtttccacccttatattcaaacagatttttgtgag
tttcaaatggagctcatcacaccagttgctaaatctaccactgaggcccgacgttttctt
ggagccattaccgatgtagctggacgttccatcagtaaagatgaacttctctggcccttg
tccatgccacctcgtatcaaggcccaagaaatccaagttgctcaactggaaaatgaattc
gaacgccattatcgcaactacttggctgaaaaatacggaaccaaactacaagctatctca
ggtatccactataatatggaactagggaaagatttggttgaggccctattcaaagaaagt
aaccagactgatatgattgctttcaagaacgccctctatcttaagctggctcagaactat
ttgcgctaccgttgggtgattacctatctctttggtgctgcacctgttgctgagcaaggc
ttcttcgaccaagaagtgccagaacccgtgcgttccttccgtaacagtgaccatggttat
gtcaataaggaagaaatccaagtatcttttgcaagcctagaagattatgtctctgccatc
gaaaactatatcgaacaaggagatttgattgcagagaaggaattctactcagctgttcgt
ttccgtggacaaaaggttaatcgttccttccttgacaagggaatcacctatctggaattc
cgtaacttcgacctcaacccctttgagcgtatcggtattagccaaactaccatggatacc
gtacacctactccttctagccttcctctggatggatgcctctgaaaatgtcgatcagtct
cttgctcaaggtcacgtgctgaatgaaaaaatcgccctctctcatcctttagagcctcta
ccatctgaaactgaaactcaaaacattacgacggctctggaccaactggtgcaacatttt
ggcctaggtgactatcatcaagatttggtcaagcaagttaaagatgcctttgctgatcct
agccagacactagcagcccaactcttacctcatatcaaagacaagtcccttgctgacttt
gcccttgacaaggctcttgcctatcatgattacgactggactgcccactatgctcttaag
ggttatgaggagatggaactctctactcagatgctactctttgatgccattcaaaagggg
attcattttgaaatcctagatgagcaggatcagttccttaaactctggcataaagatcat
gttgagtacgtcaaaaatggtaacatgacctcaaaagacaactatgtagtacctcttgcc
atggctaataaaaccgtgaccaaaaaaatcctggctgatgctggtttccctgttcccgct
ggcgacgaatttaccagtctagaacaaggtctagcttattatcctcttatcaaggacaag
caaattgtggttaaaccaaaatcaaccaactttggtctgggcatttccattttccaagag
cctgccagccttgataactataagaaagccctagagattgcctttgcagaagatacagct
gttcttgttgaagaatttatcccaggaaccgaataccgtttcttcattctggatgggcgc
tgtgaggctgtcctccttcgtgtcgctgccaatgttgtcggtgatggcaaacacaccatt
cgtgaattggtcgctcagaaaaatgccaatccattgcgaggacgtgatcaccgctcacca
ctggaaatcattgagctaggagacatcgaacaactgatgttaacgcaacagggttatacc
cctgatgatattctcccagaagggaaaaaggtcaatctacgtcgtaattctaacatttct
acgggtggtgactctattgatgtcactgagaccatggattcctcttaccaagaattagct
gctgctatggcgactagcatgggcgcttgggcttgtggggttgacctcattattccagat
gaaacccaacctgctagcaaagaaaaccctcattgcacctgcatcgagctcaactttaac
ccttctatgtatatgcacacctactgtgctgaaggacctggacaggctatcacttcaaaa
atcttagacaagctttttccagaagttgccacaaatcaaaactaa
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