Streptococcus salivarius CCHSS3: SALIVB_1198
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Entry
SALIVB_1198 CDS
T01580
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase (Alpha-isopropylmalate synthase) (Alpha-IPM synthetase)
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ssr
Streptococcus salivarius CCHSS3
Pathway
ssr00290
Valine, leucine and isoleucine biosynthesis
ssr00620
Pyruvate metabolism
ssr01100
Metabolic pathways
ssr01110
Biosynthesis of secondary metabolites
ssr01210
2-Oxocarboxylic acid metabolism
ssr01230
Biosynthesis of amino acids
Module
ssr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ssr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
SALIVB_1198 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
SALIVB_1198 (leuA)
Enzymes [BR:
ssr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
SALIVB_1198 (leuA)
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Guanylate_kin
MRP
Motif
Other DBs
NCBI-ProteinID:
CCB93480
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Position
complement(1294620..1296176)
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AA seq
518 aa
AA seq
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MRKVEFFDTSLRDGEQTPGVNFSIKEKVAIAKQLEKWGISVIEAGFPAASPDSFEAVKQI
AEAMTTTSVTGLARSVKSDIDACYEALKDAKYPQIHVFIATSPIHREFKLKKSKEEILEA
VKEHVSYARSKFEVVEFSPEDATRTELDFLTEVVQTAVDAGASYINIPDTVGFTTPEEFA
RIFDHLTENIKSDHKVVFGVHCHDDLGMATANTLTAIKHGAGRVQGTVNGIGERAGNVAL
EEVAVALKIREDFFQATSDIVLNETMNTSELVSRFSGIPVPKNKAVVGGNAFSHESGIHQ
DGVLKNPQTYEIFTPELVGVKSNSLPLGKLSGRHAFVEKLKELELDFVEEDIKPLFAKFK
ILAGKKHDITDADIRALVAGTSVDNPEGFHFEDLRLTTNADETITATVSLANEDGESVEF
LANGQGSVEAIFNAIDKFFNQTVRLTSYNIDAVTDGIDAQARVLVTVENVDTDTIFNASG
LDFDVLKASAIAYINANTLVQKENAGEMARKVSYRDLP
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgcgtaaagttgaattttttgatacaagtcttcgtgatggggaacaaacacctggtgtt
aacttctcaatcaaagaaaaagttgctattgctaagcaacttgaaaaatggggaatttct
gtaattgaagctggtttccctgcagctagcccagattcatttgaagcagtaaaacaaatt
gcagaagctatgacaacaacttctgttactggcttggctcgttcagtaaaatctgatatt
gatgcttgttatgaagctttgaaagatgctaagtatccacaaattcatgtctttatcgcg
acaagtcctattcaccgtgagtttaaattgaagaaatcaaaagaagaaattcttgaagct
gtaaaagaacatgtgtcatatgcacgttcaaaatttgaagttgttgagttttctcctgaa
gatgctactcgtactgagcttgatttcttgactgaagttgttcaaacagcagttgatgct
ggtgcctcatatattaatattcctgatacagttggctttacgactccagaagagtttgca
cgtatttttgatcacttgactgaaaatattaaatcagaccataaagttgtctttggtgtt
cactgtcacgatgacctcggtatggcaactgcaaatactttgacagcaattaaacatggt
gctggacgtgttcagggaacagtcaacggtattggtgagcgtgcgggtaatgttgctctt
gaagaagtagctgtcgctttgaaaattcgtgaagactttttccaagcaacaagtgatatt
gttcttaatgaaacaatgaatacttcagagcttgtttctcgcttctctggaattcctgtt
cctaaaaataaagctgttgttggtggaaatgccttctctcatgaatcaggtatccaccaa
gatggtgttcttaagaacccacaaacttatgaaatcttcacaccagaattggtaggtgtg
aagagtaacagtcttcctcttggtaaattgtcaggacgtcatgcctttgttgaaaaattg
aaagaacttgagcttgactttgttgaagaagatatcaagccactctttgccaaattcaaa
atcttggctgggaaaaaacatgatattactgatgcagacattcgtgcacttgttgctggt
actagtgtagataatccagaaggtttccacttcgaagatcttcgtttgaccactaatgct
gatgaaacaatcactgctacagttagcttggctaatgaagacggtgaatctgtagaattt
ttggcaaacggtcaaggatcagttgaagctattttcaatgctattgataaattcttcaac
caaacagttcgcttgacttcttataatattgacgctgtaactgatggtattgatgcacaa
gcgcgtgtacttgtaactgtcgaaaatgtagatacagatactattttcaatgcatctggt
ttggactttgatgtcttgaaagcatcagcaattgcctatatcaatgctaatacattggtt
caaaaagaaaatgctggtgagatggcacgtaaggtttcttatcgtgaccttccataa
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