Streptomyces sp. SirexAA-E: SACTE_2436
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Entry
SACTE_2436 CDS
T01601
Name
(GenBank) Uroporphyrinogen III synthase HEM4
KO
K01719
uroporphyrinogen-III synthase [EC:
4.2.1.75
]
Organism
ssx
Streptomyces sp. SirexAA-E
Pathway
ssx00860
Porphyrin metabolism
ssx01100
Metabolic pathways
ssx01110
Biosynthesis of secondary metabolites
ssx01120
Microbial metabolism in diverse environments
ssx01240
Biosynthesis of cofactors
Module
ssx_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
ssx_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
ssx_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
ssx00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
SACTE_2436
Enzymes [BR:
ssx01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
SACTE_2436
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Motif
Pfam:
HEM4
Trans_reg_C
Motif
Other DBs
NCBI-ProteinID:
AEN10324
UniProt:
G2NKW9
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Position
complement(2720428..2721573)
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AA seq
381 aa
AA seq
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MHDDDAQHGPLAGFTVGVTAARRAEELGTLLTRRGAAVLHAPALRIVPLADDSELLAATE
ELLDDVPDVVIATTAIGFRGWVEAADGWGIGDRLLEVLRGGELLARGPKVKGAIRAAGLT
EAWSPGSESMAEVLDRLLGEGVEGRRIALQLHGEPLPGFVDALREAGAEVVGVPVYRWMP
PQDIAPLDRMLDVTVARGLDALTFTSAPAAASYLNRAESRGMLPQVLSALGHDVVVACVG
PVTALPLQARGIDTVQPERFRLGPLVQLLCAHLPARARALPVAGHLVEIRGHAVLVDRAL
HPVPPAGMALLHALARRPGWVVSRADLLRALPGSGTDEHAVETAMARLRTVLGAPELIQT
VVKRGYRLALDPAADTRYDGP
NT seq
1146 nt
NT seq
+upstream
nt +downstream
nt
atgcacgacgacgacgcacagcacgggcctctcgcgggcttcacggtcggggtgaccgca
gcccgtcgcgccgaggagctggggacgctcctcacgcgccggggcgccgcggtcctgcac
gcgccagcgctgcggatcgtgcctctcgcggacgacagcgaactcctcgccgccaccgag
gaactgctcgacgacgtgcccgacgtggtgatcgccaccaccgccatcgggttccgcggc
tgggtcgaggccgccgacggctggggcatcggcgaccggctgctggaggtgctgcgcggg
ggcgaactgctggcccgggggcccaaggtcaagggcgccatccgggccgccgggctcacc
gaggcgtggtcgcccgggtcggagtccatggcggaggtcctggaccggctgctgggcgag
ggcgtcgaagggcggcggatcgccctccaactgcacggcgaacccctgcccggcttcgtc
gatgcgctccgggaggcgggggcagaggtcgtcggcgtcccggtctaccggtggatgccc
ccgcaggacatcgcccccctcgaccggatgctggacgtcacggtggcccgcggcctggac
gccctgaccttcaccagcgcccccgccgccgcctcgtacctgaaccgggcggagtcgcgc
ggcatgctcccccaggtgctgtccgcactgggccacgacgtcgtcgtggcctgcgtcggc
ccggtcaccgcgctgcccctccaggcccggggcatcgacaccgtccagccggaacgcttc
cggctcggcccgctcgtccaactgctctgcgcccatctgcccgcacgcgcccgggccctg
ccggtcgccggacacctggtcgagatccgggggcacgccgtcctggtcgacagggcgctg
cacccggtgccgcccgccggcatggccctgctgcacgcgctcgcccgccggccgggctgg
gtggtctcccgcgccgacctgctgcgcgcgctgcccggcagcggcaccgacgagcacgcc
gtggagacggcgatggcccggctgcgtacggtgctcggggcgcccgagctgatccagacc
gtcgtcaagcgcggctaccggctcgccctggaccccgcggcggacaccaggtacgacggc
ccctga
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