Symphalangus syndactylus (siamang): 129457446
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Entry
129457446 CDS
T10134
Symbol
PDE8B
Name
(RefSeq) high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B isoform X1
KO
K18437
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8 [EC:
3.1.4.53
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00230
Purine metabolism
ssyn01100
Metabolic pathways
ssyn04927
Cortisol synthesis and secretion
ssyn04934
Cushing syndrome
ssyn05032
Morphine addiction
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
129457446 (PDE8B)
09150 Organismal Systems
09152 Endocrine system
04927 Cortisol synthesis and secretion
129457446 (PDE8B)
09160 Human Diseases
09165 Substance dependence
05032 Morphine addiction
129457446 (PDE8B)
09167 Endocrine and metabolic disease
04934 Cushing syndrome
129457446 (PDE8B)
Enzymes [BR:
ssyn01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.53 3',5'-cyclic-AMP phosphodiesterase
129457446 (PDE8B)
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Ortholog
Paralog
GFIT
Motif
Pfam:
PDEase_I
PDE8A_N
PDE8
PAS_9
PAS
PAS_3
PDE8_3rd
PAS_4
PAS_8
DHH
Motif
Other DBs
NCBI-GeneID:
129457446
NCBI-ProteinID:
XP_055088566
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All DBs
Position
11:64700645..64955531
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AA seq
906 aa
AA seq
DB search
MGCAPSIHVSQSGVIYCRDSDESSSPRQTTSVSQGPAAPLPGLFVQTDAADAIPPSRASG
PPSAARVRRARTELGSGSSAGSAAPAATTSRGRRRHCCSSAEAETQTCYTSVKIGASQTS
SNLSMEKVDAYLHQQVSSAEVRIGPMRLTQDPIQVLLIFAKEDSQSDGFWWACDRAGYRC
NIARTPESALECFLDKHHEIIVIDHRQTQNFDAEAVCRSIRATNPSEHTVILAVVSRVSD
DHEEASVLPLLHAGFNRRFMENSSIIACYNELIQIEHGEVRSQFKLRACNSVFTALDHCH
EAIEITSDDHVIQYVNPAFERMMGYHKGELLGKELADLPKSDKNRADLLDTINTCIKKGK
EWQGVYYARRKSGDSIQQHVKITPVIGQGGKIRHFVSLKKLCCTTDNNKQIHKIHRDSGD
NSQTEPHSFRYKNRRKESIDVKSISSRGSDAPSLQNRRYPSMARIHSMTIEAPITKVINI
INAAQENSPVTVAEALDRVLEILRTTELYSPQLGTKDEDPHTSDLVGGLMTDGLRRLSGN
EYVFTKNVHQSHSHLAMPITINDVPPCISQLLDNEESWDFNIFELEAITHKRPLVYLGLK
VFSRFGVCEFLNCSETTLRAWFQVIEANYHSSNAYHNSTHAADVLHATAFFLGKERVKGS
LDQLDEVAALIAATVHDVDHPGRTNSFLCNAGSELAVLYNDTAVLESHHTALAFQLTVKD
TKCNIFKNIDRNHYRTLRQAIIDMVLATEMTKHFEHVNKFVNSINKPMAAEIEGSDCECN
PAGKNFPENQILIKRMMIKCADVANPCRPLDLCIEWAGRISEEYFAQTDEEKRQGLPVVM
PVFDRNTCSIPKSQISFIDYFITDMFDAWDAFAHLPALMQHLADNYKHWKTLDDLKCKSL
RLPSDS
NT seq
2721 nt
NT seq
+upstream
nt +downstream
nt
atgggctgcgcccccagcatccatgtctcgcagagcggcgtgatctactgccgggactcg
gacgagtccagctcgccccgccagaccaccagcgtgtcgcagggcccggcggcacccctg
cccggcctcttcgtccagaccgacgccgccgacgccatccccccgagccgcgcgtcggga
ccccccagcgcagcccgcgtccgcagggcccgcaccgagctgggcagcggtagcagcgcg
ggttccgcagcccccgccgcgaccaccagcaggggccggaggcgccactgctgcagcagc
gccgaggccgagactcagacctgctacaccagcgtgaagattggtgcttctcaaacctct
tcaaatctgagcatggagaaagtggatgcctacctccaccagcaggtgtcttctgcggag
gtgcgcatcgggcccatgagactgacgcaggaccctattcaggttttgctgatctttgca
aaggaagatagtcagagtgatggcttctggtgggcctgtgacagagctggttatagatgc
aatattgctcggactccagagtcagcccttgaatgctttcttgataagcatcatgaaatt
atcgtaattgatcatagacaaactcagaacttcgatgcagaagcggtgtgcaggtcgatc
cgggccacaaatccctccgagcacacggtgatcctcgcagtggtttcacgagtatcggat
gaccatgaagaggcgtcagtccttcctcttctccacgcaggcttcaacaggagatttatg
gagaatagcagcataattgcttgctataatgaactgattcaaatagaacatggggaagtt
cgctcccagttcaaattacgggcctgtaattcagtgtttacagcattagatcactgtcat
gaagccatagaaataacaagtgatgaccacgtgattcagtatgtcaacccagccttcgaa
aggatgatgggctaccacaaaggtgagctcctgggaaaagaactcgctgatctgcccaaa
agcgataagaaccgggcagaccttctcgacaccatcaatacatgcatcaagaagggaaag
gagtggcagggcgtttactatgccagacggaaatccggggacagcatccaacagcacgtg
aagatcaccccagtgattggccaaggagggaaaattaggcattttgtctccctcaagaaa
ctgtgttgtaccactgacaataataagcagattcacaagattcatcgtgattcaggagac
aattctcagacagagcctcattcattcagatataagaacaggaggaaagagtccattgat
gtgaaatcgatatcatctcgaggcagtgatgcaccaagcctgcagaatcgtcgctatccg
tccatggcgaggatccactccatgaccatcgaggctcccatcacaaaggttataaatata
atcaatgcagctcaagaaaacagcccagtcacagtagcggaagccttggacagagttcta
gagattttacggaccacagaactgtactcccctcaactgggtaccaaagatgaagatccc
cacaccagtgatcttgttggaggcctgatgactgatggcttgagaaggctgtcaggaaac
gagtatgtgtttactaagaatgtgcaccagagtcacagtcaccttgcaatgccaataacc
atcaatgatgttcccccttgtatctctcaattacttgataatgaggagagctgggacttc
aacatctttgaattggaagccattacgcataaaaggccattggtttacctgggcttaaag
gtcttctctcggtttggagtatgtgaatttttaaactgttctgaaaccactcttcgtgcc
tggttccaagtgatcgaagccaactaccactcttccaatgcctaccacaactccacccat
gctgccgacgtcctgcacgccaccgctttcttccttggaaaggaaagagtaaagggcagc
ctcgatcagctggatgaggtggcagccctcattgctgccacggtccatgacgtggatcac
ccgggaaggaccaactctttcctctgcaatgcaggcagcgagcttgctgtgctctacaat
gacactgctgttctggagagtcaccacaccgccctggccttccagctcacggtcaaggac
accaaatgcaacattttcaagaatattgacaggaaccattatcgaacgctgcgccaggct
attattgacatggttttggcaacagagatgacaaaacactttgaacatgtgaataagttt
gtgaacagcatcaacaagccaatggcagctgagattgaaggcagcgactgtgaatgcaac
cctgctgggaagaacttccctgaaaaccaaatcctgatcaaacgcatgatgattaagtgt
gctgacgtggccaacccatgccgccccctggacctgtgcattgaatgggctgggaggatc
tctgaggagtattttgcacagactgatgaagagaagagacaggggctacctgtggtgatg
ccagtgtttgaccggaatacctgtagcatccccaagtctcagatctctttcattgactac
ttcataacagacatgtttgatgcttgggatgcctttgcacatctgccagccctgatgcaa
catttggctgacaactacaaacactggaagacactagatgacctaaagtgcaaaagtttg
aggcttccatctgacagctaa
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