Symphalangus syndactylus (siamang): 129459456
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Entry
129459456 CDS
T10134
Symbol
NPC1
Name
(RefSeq) NPC intracellular cholesterol transporter 1 isoform X2
KO
K12385
Niemann-Pick C1 protein
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn03265
Virion - Ebolavirus, Lyssavirus and Morbillivirus
ssyn04142
Lysosome
ssyn04979
Cholesterol metabolism
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03265 Virion - Ebolavirus, Lyssavirus and Morbillivirus
129459456 (NPC1)
09140 Cellular Processes
09141 Transport and catabolism
04142 Lysosome
129459456 (NPC1)
09150 Organismal Systems
09154 Digestive system
04979 Cholesterol metabolism
129459456 (NPC1)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
02000 Transporters [BR:
ssyn02000
]
129459456 (NPC1)
Transporters [BR:
ssyn02000
]
Solute carrier family (SLC)
SLC65: NPC-type cholesterol transporter
129459456 (NPC1)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
NPC1_MLD
NPC1_N
Sterol-sensing
Patched
MMPL
ACR_tran
Motif
Other DBs
NCBI-GeneID:
129459456
NCBI-ProteinID:
XP_055092158
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All DBs
Position
1:63137335..63191029
Genome browser
AA seq
1277 aa
AA seq
DB search
MSARGLALGLLLLLLCPAQVFSQSCVWYGECGIAYGDKRYNCEYSGPPKPLPKDGYDLVQ
ELCPGFFFGNVSLCCDVQQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQF
LNVTATEVYVDPVTNQTKTNVKELQYYVGQSFASAMYNACRDVEAPSSNDKALGLLCGKD
ADACNATNWIEYMFNKDNGQAPFTITPVFSDFPIHGMEPMNNATKGCDESVDEVTAPCSC
QDCSIVCGPKPQPPPPPAPWTILGLDAMYVIMWITYMAFLLVFFGAFFAVWCYRKRYFVS
EYTPIDSNIAFSVNASDKGEASCCDPVSAAFEGCLRRLFTRWGSFCVRNPGCVIFFSLVF
ITVCSSGLVFVRVTTNPVDLWSAPSSQARLEKEYFDQHFGPFFRTEQLIIRAPLTDKHTY
QPYPSGADVPFGPPLDIQILHQVLDLQIAIENITASYNNETVTLQDICLAPLSPYNTNCT
IMSVLNYFQNSHSVLDHKKGDDFFVYADYHTHFLYCVRAPASLNDTSLLHDPCLGTFGGP
VFPWLVLGGYDDQNYNNATALVITFPVNNYYNDTEKLQRAQAWEKEFINFVKSYKNPNLT
ISFTAERSIEDELNRESDSDVFTVVISYAIMFLYISLALGHIKSCRRLLVDSKVSLGIAG
ILIVLSSVACSLGVFSYIGLPLTLIVIEVIPFLVLAVGVDNIFILVQAYQRDERLQGETL
DQQLGRVLGEVAPSMFLSSFSETIAFFLGALSVMPAVHTFSLFAGLAVFIDFLLQITCFV
SLLGLDIKRQEKNRLDIFCCVRGAEDGTSVQASESCLFRFFKNSYSPLLLKDWMRPIVIA
IFVGVLSFSIAVLNKVDIGLEQSLSMPDDSYVVDYFKSISQYLHAGPPVYFVLEEGHNYT
SPKGQNMVCGGMGCNNDSLVQQIFNAAQLDNYTRIGFAPSSWIDDYFDWVKPQSSCCRVD
NITDQFCNASVVDPACVRCRPLTPEGKQRPQGGDFMRFLPMFLSDNPNPKCGKGGHAAYS
SAVNILGNGTRVGATYFMTYHTVLQTSADFIDALKKARLIASNVTETMGINGSAYRVFPY
SVFYVFYEQYLTIIDDTIFNLGVSLGAIFLVTVVLLGCELWSAVIMCATIAMVLVNMFGV
MWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSTKGSRVERAEEALAHMGSSVFSG
ITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNKARSC
ATEERYKGTERERLLNF
NT seq
3834 nt
NT seq
+upstream
nt +downstream
nt
atgagcgctcgcggcctggcccttggcctcctcctgctgctactgtgtccagcgcaggtg
ttttcacagtcgtgtgtttggtatggagagtgtggaattgcatatggggacaagaggtac
aattgcgaatattctggcccaccaaaaccattgccaaaggatggatatgacttagtgcag
gaactctgtccaggattcttctttggcaatgtcagtctctgttgtgatgttcagcagctt
cagacactaaaagacaacctgcagctgcccctacagtttctgtccagatgtccatcctgt
ttttataacctactgaacctgttttgtgagctgacatgtagccctcgacagagtcagttt
ttgaatgttacagcaactgaagtttatgttgatcctgttacaaaccagacgaaaacaaat
gtgaaagagttacagtactacgttggacagagttttgccagcgcaatgtacaatgcctgc
cgggacgtggaggccccctcaagtaatgacaaggccctgggacttctgtgtgggaaggac
gctgatgcctgtaatgccaccaactggattgaatacatgttcaataaggacaacggacag
gcaccttttaccatcactcccgtgttttcagattttccaatccatgggatggagcccatg
aataatgccaccaaaggctgtgacgagtctgtggatgaggtcacagcgccgtgtagctgc
caagactgctctattgtctgtggccccaagccccagcccccacctcctcctgctccctgg
acgatcctcggcttggacgccatgtatgtcatcatgtggatcacctacatggcgtttttg
cttgtgttttttggagcattttttgcagtgtggtgctacagaaaacggtattttgtctcc
gagtacactcccatcgatagcaatatagctttttctgttaatgcaagtgacaaaggagag
gcgtcctgctgtgaccctgtcagtgcagcatttgagggctgcttgaggcggctgttcaca
cgctgggggtctttctgtgtccgaaaccctggctgtgtcattttcttctctctggtcttc
attactgtgtgttcatcaggcctggtgtttgtccgggtcacaaccaatccagttgacctc
tggtcagcccccagcagccaggctcgcctggaaaaagagtactttgaccagcactttggg
cctttcttccggacggagcagctcatcatccgggcccctctcactgacaaacacacttac
cagccgtacccttcgggagctgatgtaccctttggacctccgcttgacatacagatactg
caccaggttcttgacttacaaatagccatcgaaaacattactgcctcttataacaatgag
actgtgacacttcaagatatctgcttggcccctctctcaccatataacacgaactgcacc
attatgagtgtgttaaattacttccagaacagccattctgtgctggaccacaagaaaggg
gacgacttctttgtgtatgccgattaccacacgcactttctgtactgcgtacgggctcct
gcctctctgaatgatacaagtttgctccatgacccttgtctgggtacgtttggtggacca
gtgttcccgtggcttgtgttgggaggctatgatgatcaaaactacaataacgccactgcc
cttgtgattaccttccctgtcaataattactataatgatacagagaagctccagagggcc
caggcctgggaaaaagagtttattaattttgtgaaaagctacaagaatcccaatctgacc
atttccttcactgctgaacgaagtattgaagatgaactaaatcgtgaaagtgacagtgat
gtcttcaccgttgtgattagctatgccatcatgtttctgtatatttccctagccttgggg
cacatcaaaagctgtcgtaggcttctggtggattcgaaggtctcactaggcatcgcgggc
atcctgatcgtgctgagctcggtggcttgctccttgggcgtcttcagctacattgggttg
cccttgaccctcattgtgattgaagtcatcccattcctggtgctggctgttggagtggac
aacatcttcattctggtgcaggcctaccagagagatgaacgtcttcaaggggaaaccctg
gatcagcagctgggcagggtcctaggagaagtggctcccagtatgttcctgtcatccttt
tctgagaccatagcatttttcttaggagcattgtccgtgatgccagccgtgcacacgttc
tctctctttgcgggattggcagtcttcattgactttcttctgcagattacctgtttcgtg
agtctcttggggttagacattaaacgtcaagagaaaaatcggctagacatcttttgctgt
gtcagaggtgctgaagatggaacaagcgtccaggcctcagagagctgtttgtttcgcttc
ttcaaaaactcctattctccacttctgctaaaggactggatgagaccaattgtgatagca
atatttgtgggtgttctgtcattcagcatcgcagtcctgaacaaagtagatattggattg
gaacagtctctttcgatgccagatgactcctacgtggtggattatttcaaatccatcagt
cagtacctgcatgcgggtccgcctgtgtactttgtcctggaggaagggcacaactacact
tctcccaaggggcagaacatggtgtgtggcggcatgggctgcaacaacgattccctggtg
cagcagatatttaacgcggcgcagctggacaactatacccgaataggcttcgccccctcg
tcctggatcgacgattatttcgactgggtgaagccacagtcgtcttgctgtcgagtggac
aatatcactgaccagttctgcaatgcttcagtggttgaccctgcctgcgtccgctgcagg
cctctgactccggaaggcaaacagaggcctcagggtggagacttcatgagattcctgccc
atgttcctttcggataaccctaaccccaagtgtggcaaagggggacatgctgcctatagt
tctgcagttaacatccttggcaatggcaccagggtcggagccacgtacttcatgacctac
cacaccgtgctgcagacctctgctgactttattgacgctctgaagaaagcccgacttata
gccagtaatgtcaccgaaaccatgggcattaacggcagtgcctaccgggtatttccttac
agtgtgttttatgtcttctacgagcagtacctgaccatcattgacgacactatcttcaac
ctcggcgtgtccctgggcgcgatatttctggtgaccgtggtcctcctgggctgtgagctc
tggtccgcagtcatcatgtgtgccaccatcgccatggtcttggtcaacatgtttggagtt
atgtggctctggggcatcagtctgaacgctgtatccttggtcaacctggtgatgagctgt
ggcatctctgtggagttctgcagccacataaccagagcgttcacggtgagcacgaaaggc
agccgcgtggagcgcgcagaagaggcactcgcccacatgggcagctccgtgttcagtgga
atcacacttacaaaatttggagggattgtggtgttggcttttgccaaatctcaaattttc
cagatattctacttcaggatgtatttggccatggtcttactgggagccactcacggatta
atatttctccctgtcttactcagttacatagggccatcagtaaataaagccagaagttgt
gccactgaagagcgatacaaaggaacagagcgcgaacggcttctaaatttctag
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