Symphalangus syndactylus (siamang): 129459737
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Entry
129459737 CDS
T10134
Symbol
TYMS
Name
(RefSeq) thymidylate synthase isoform X1
KO
K00560
thymidylate synthase [EC:
2.1.1.45
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00240
Pyrimidine metabolism
ssyn00670
One carbon pool by folate
ssyn01100
Metabolic pathways
ssyn01232
Nucleotide metabolism
ssyn01523
Antifolate resistance
ssyn04981
Folate transport and metabolism
Module
ssyn_M00938
Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
129459737 (TYMS)
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
129459737 (TYMS)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
129459737 (TYMS)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
129459737 (TYMS)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.45 thymidylate synthase
129459737 (TYMS)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Thymidylat_synt
Motif
Other DBs
NCBI-GeneID:
129459737
NCBI-ProteinID:
XP_055092844
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Position
1:66443239..66455716
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AA seq
313 aa
AA seq
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MPVAGSELPRRPLPAAAQERDAELRPPHGELQYLGQIEHILRCGVRKDDRTGTGTLSVFG
MQARYSLRDEFPLLTTKRVFWKGVLEELLWFIKGSTNAKELSSKGVKIWDANGSRDFLDS
LGFSTREEGDLGPVYGFQWRHFGAEYRDMESDYSGQGVDQLQRVIDTIKTNPDDRRIIMC
AWNPRDLPLMALPPCHALCQFYVVNSELSCQLYQRSGDMGLGVPFNIASYALLTYMIAHI
TGLKPGDFIHTLGDAHIYLNHIEPLKIQLQREPRPFPKLKILRKVEKIDDFKAEDFQIEG
YNPHPTIKMEMAV
NT seq
942 nt
NT seq
+upstream
nt +downstream
nt
atgcccgtcgccggctccgagctgccgcgccggcccttgccggccgccgcacaggagcgg
gacgctgagctgcgtccgccgcacggggagctgcagtacctggggcagatcgagcacatt
ctccgctgcggcgtcaggaaggacgaccgcacgggcaccggcaccctgtcggtattcggc
atgcaggcgcgctatagcctgagagatgaatttcctctgctgacaaccaaacgtgtgttc
tggaagggtgttttggaggagttgctgtggtttatcaagggatccacaaatgctaaagag
ctgtcttccaagggagtgaaaatctgggatgccaatggatcccgagactttttggacagc
ctgggattctccaccagagaagaaggggacttgggcccagtttatggcttccagtggagg
cattttggggcagaatacagagatatggaatcagattattcaggacagggagttgaccaa
ctgcaaagagtgattgacaccatcaaaaccaaccctgacgacagaagaatcatcatgtgc
gcttggaatccaagagatcttcctctgatggcgctgcctccatgccatgccctctgccag
ttctatgtggtgaacagtgagctgtcctgccagctgtaccagagatcgggagacatgggc
ctaggtgtgcctttcaacatcgccagctacgccctgctcacgtacatgattgcacacatc
acgggcctgaagccaggtgactttatacacactttgggagatgcacatatttacctgaat
cacatcgagccactgaaaattcagcttcagcgagaacccagacctttcccaaagctcaag
attcttcgaaaagttgagaaaattgatgacttcaaagctgaagactttcagattgaaggg
tacaatccacatccaactattaaaatggaaatggctgtttag
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