Symphalangus syndactylus (siamang): 129460409
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Entry
129460409 CDS
T10134
Symbol
TYK2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2 isoform X1
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn04217
Necroptosis
ssyn04380
Osteoclast differentiation
ssyn04620
Toll-like receptor signaling pathway
ssyn04621
NOD-like receptor signaling pathway
ssyn04630
JAK-STAT signaling pathway
ssyn04658
Th1 and Th2 cell differentiation
ssyn04659
Th17 cell differentiation
ssyn05145
Toxoplasmosis
ssyn05160
Hepatitis C
ssyn05161
Hepatitis B
ssyn05162
Measles
ssyn05164
Influenza A
ssyn05165
Human papillomavirus infection
ssyn05167
Kaposi sarcoma-associated herpesvirus infection
ssyn05168
Herpes simplex virus 1 infection
ssyn05169
Epstein-Barr virus infection
ssyn05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
129460409 (TYK2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
129460409 (TYK2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
129460409 (TYK2)
04621 NOD-like receptor signaling pathway
129460409 (TYK2)
04658 Th1 and Th2 cell differentiation
129460409 (TYK2)
04659 Th17 cell differentiation
129460409 (TYK2)
09158 Development and regeneration
04380 Osteoclast differentiation
129460409 (TYK2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
129460409 (TYK2)
05160 Hepatitis C
129460409 (TYK2)
05171 Coronavirus disease - COVID-19
129460409 (TYK2)
05164 Influenza A
129460409 (TYK2)
05162 Measles
129460409 (TYK2)
05168 Herpes simplex virus 1 infection
129460409 (TYK2)
05167 Kaposi sarcoma-associated herpesvirus infection
129460409 (TYK2)
05169 Epstein-Barr virus infection
129460409 (TYK2)
05165 Human papillomavirus infection
129460409 (TYK2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
129460409 (TYK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssyn01001
]
129460409 (TYK2)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
129460409 (TYK2)
Protein kinases [BR:
ssyn01001
]
Non-receptor tyrosine kinases
JAK family [OT]
129460409 (TYK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kinase-like
Kdo
ABC1
Motif
Other DBs
NCBI-GeneID:
129460409
NCBI-ProteinID:
XP_055094178
LinkDB
All DBs
Position
13:complement(36515411..36543781)
Genome browser
AA seq
1202 aa
AA seq
DB search
MPAEPPAGSMPLRHWGTARGSKPVGDGAQPMAAMGGLKVLLHWAGPGGGEPWVTFSESSL
TAEEVCIHIAHKVGITPPCFNLFALFDAQAQVWLPPNHILEIPRDASLMLYFRIRFYFRN
WHGMNPQEPAVYRCGPPGTEASSDHTAQGMQLLDPASFEYLFEQGKHEFVNDVASLWELS
SEEEIHHFKNESLGMAFLHLCHLALRHGIPLEEVAKKTSFKDCIPRSFRRHIRQHSALTR
LRLRNVFRRFLRDFQPGRLSQQMVMVKYLATLERLAPRFGTERVPVCHLRLLAQAEGEPC
YIRDSGEAPTDPGPESAAGPPTHEVLVTGTGGIQWWPVQEEVNKEEVSKASSGSSGRNLQ
ASLSGRKAKAHKAVGQPADRPQEPLWAYFCDFRDITHVVLKERSVSIHRQDNKCLELSLP
SRAAALSFVSLVDGYFRLTADSSHYLCHEVAPPRLVMSIRDGIHGPLLEPFVQAKLRPED
GLYLIHWSTSHPYRLILTVAQRSQAPDGMQSLRLRKFPIEQQNGAFVLEGWGRSFPSVRE
LGAALQGCLLRAGDDCFSLRRCCLPQPGETSNLIIMRGARASSGTFNLSQLSFHRVDQKE
ITQLSHLGQGTRTNVYEGRLRVEGSGDPEEGKMDDEDPLVPGRDRGQELRVVLKVLDPSH
HDIALAFYETASLMSQVSHAHLAFVHGVCVRGPENIMVTEYVEHGPLDVWLRRERGHVPM
AWKMMVAQQLASALSYLENKNLVHGNVCGRNILLARLGLAEGTSPFIKLSDPGVGLGALS
REERVDRIPWMAPECLPGGPNSLSTAMDKWGFGATLLEICFDGEAPLQSRNPSEKEHFYQ
RQHRLPEPSCPELATLTSQCLTYEPTQRPSFRTILRDLTRLQPHTLPDLADILTVNPDSL
ASDPTVFHKRYLKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKADCGPQHRLGWK
QEIDILRKLYHEHIVKYKGCCEDQGEKSLQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQ
QICEGMAYLHAQHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPV
FWYAPECLKEYKFYYASDVWSFGVTLYELLTHCDSSQSPPTKFLELIGVAQGQMTVLRLT
ELLERGERLPRPNKCPCEVYHLMKNCWETEASFRPTFENLIPILKTVHEKYQGQAPSVFS
VC
NT seq
3609 nt
NT seq
+upstream
nt +downstream
nt
atgcctgctgagccgcctgccgggagcatgcctctgcgccactgggggacggccaggggc
agcaagcctgttggggatggagcccagcccatggctgccatggggggcctgaaggtgctt
ctgcactgggctggtccaggcggtggggagccctgggtcactttcagtgagtcatcgctg
acagctgaggaagtctgcatccacattgcacataaagttggtatcactcctccttgtttc
aatctcttcgccctcttcgatgctcaagcccaagtctggttgcccccaaaccacatcctg
gagatccccagagacgcaagtctgatgctatatttccgcataaggttttatttccggaac
tggcatggcatgaatcctcaggaaccggctgtgtaccgttgtgggcccccaggaaccgag
gcatcttcagatcacacagcacaggggatgcaactcctggacccagcctcatttgagtac
ctctttgagcagggcaagcatgagtttgtgaatgacgtggcatcactgtgggagctgtcg
agcgaggaggagatccaccactttaagaatgagagcctgggcatggcctttctgcacctc
tgtcacctcgctctccgccatggcatccccctggaggaggtggccaagaagaccagcttc
aaggactgcatcccgcgctccttccgtcggcatatccggcagcacagcgccctgacccgg
ctgcgccttcggaacgtcttccgcaggttcctgcgggacttccagccgggccgactctcc
cagcagatggtcatggtcaaatacctagccacactcgagcggctggcaccccgctttggc
acagagcgtgtgcccgtgtgccacctgaggctgctggcccaggctgagggggagccctgc
tacatcagggacagtggggaggcccctacagaccctggccctgagtctgctgctgggccc
ccaacccacgaggtgctggtgacaggcactggtggcatccagtggtggccagtacaggag
gaggtgaacaaggaggaggtgagtaaggcttctagtggtagcagtggcaggaacctccaa
gccagcctgtctgggaggaaggccaaggctcacaaggcagttggccagccggcggacagg
ccccaggagccactgtgggcctacttctgcgacttccgggacatcacccacgtggtgctg
aaagagcgcagtgtcagcatccaccggcaggacaacaagtgcctggagctgagtctgcct
tcccgggctgcggcgctgtccttcgtgtcgctggtggacggctatttccgcctgacggcc
gactccagccactacctgtgccatgaggtggctcccccacggctggtgatgagcatccgg
gatgggatccacggacctctgctggagccatttgtgcaggccaagctgcggcccgaggac
ggcctgtatctcattcactggagcaccagccacccctaccgcctgatcctcacagtggcc
cagcgtagccaggcaccagacggcatgcagagcttgcggctccggaagttccccatagag
cagcagaacggggccttcgtgctggagggctggggccggtccttccccagcgttcgggaa
cttggggctgccttgcagggctgcttgctgagggccggggatgactgcttctctctgcgt
cgctgttgcctgccccaaccaggagaaacctccaatctcatcatcatgcggggggctcgg
gccagcagcgggacattcaacctcagccagctcagcttccaccgggttgaccagaaggag
atcacccagctgtcccacttgggccagggcacaaggaccaatgtgtatgagggccgcctg
cgagtggagggcagcggggaccctgaggagggcaagatggatgacgaggaccccctcgtg
cctggcagggaccgtgggcaggagctacgagtggtgctcaaagtgctggaccctagtcac
catgacattgccctggccttctacgagacagccagcctcatgagccaggtctcccacgcg
cacctggccttcgtgcatggcgtctgtgtgcgtggtcctgaaaatatcatggtgacagag
tacgtggagcacggacccctggatgtgtggttgcggagggagcggggccatgtgcccatg
gcttggaagatgatggtggcccagcagctggccagtgccctcagctacctggagaacaag
aaccttgttcatggtaatgtgtgtggccggaacatcctgctggcccggctggggctggca
gagggcaccagccccttcatcaagctgagtgatcccggcgtgggcctgggcgccctctcc
agggaggagcgggtggacaggatcccctggatggcccccgaatgcctaccaggtgggccc
aacagcctaagcaccgccatggacaagtgggggtttggtgccaccctcctggagatctgc
tttgacggagaggcccctctgcagagccgcaacccctccgagaaggagcatttctaccag
aggcagcaccggctgcctgagccctcctgcccagagctggccacactcaccagccagtgt
ctgacctatgagccaacccagaggccatcattccgcaccatcctgcgtgacctcacccgg
ctgcagccccacactcttccagatcttgctgacatcttgactgtgaacccggactcactg
gcgtcagaccctacggttttccacaagcgctatttgaaaaagatccgagatctgggcgag
ggtcacttcggcaaggtcagcttgtactgctacgatccgaccaacgacggcactggcgag
atggtggcggtgaaagccctcaaggcagactgcggcccccagcaccgcttgggctggaag
caggagattgacattctgcgcaagctctatcacgagcacatcgtcaagtacaagggctgc
tgcgaggaccaaggcgagaagtcgctgcagctggtcatggagtacgtgcccctgggcagc
ctccgagactacctgccccggcacagcgtcgggctggcccagctgctgctcttcgcccag
cagatctgcgagggcatggcctatctgcacgcgcagcactacatccaccgagacctagcc
gcgcgcaacgtgcttctggacaacgacaggctggtcaagatcggggactttggcctagcc
aaagccgtgcccgaaggccacgagtactaccgcgtgcgcgaggatggggacagccccgtg
ttctggtatgccccagagtgcctgaaggagtataagttctactatgcgtccgatgtctgg
tcgttcggggtgaccctgtatgagctgctgacgcactgtgactccagccagagcccccct
acgaaattccttgagctcataggcgttgctcagggtcagatgacagttctgagactcacc
gagttgctggaacgaggggagaggctgccacggcccaacaaatgtccctgtgaggtctat
catctcatgaagaactgctgggagacagaggcgtccttccgcccaacctttgagaacctc
atacccatcctgaagacagtccatgagaagtaccaaggccaggctccttcagtgttcagc
gtgtgctga
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integrated database retrieval system
