Symphalangus syndactylus (siamang): 129466425
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Entry
129466425 CDS
T10134
Symbol
BCKDHA
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial isoform X1
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00280
Valine, leucine and isoleucine degradation
ssyn00640
Propanoate metabolism
ssyn00785
Lipoic acid metabolism
ssyn01100
Metabolic pathways
ssyn01210
2-Oxocarboxylic acid metabolism
Module
ssyn_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
129466425 (BCKDHA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
129466425 (BCKDHA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
129466425 (BCKDHA)
Enzymes [BR:
ssyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
129466425 (BCKDHA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
129466425
NCBI-ProteinID:
XP_055105896
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Position
17:complement(20889775..20919793)
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AA seq
446 aa
AA seq
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MAVAIVAARVWRPNRGLSQAALLLLLRRPGARGLARSHPHRQQQQFSSLDDKPQFPGASA
EFIDKLEFIQPNVISGIPIYRVMDRQGQIINPSEDPHLPKEKVLKLYKSMTLLNTMDRIL
YESQRQGRISFYMTNYGEEGTHVGSAAALDNTDLVFGQYREAGVLMYRDYPLELFMAQCY
GNISDLGKGRQMPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKRANANRVVICYFGEG
AASEGDAHAGFNFAATLECPIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYGIMSIRVD
GNDVFAVYNATKEARRRAVAENQPFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDH
PISRLRHYLLSQGWWDEEQEKAWRKQSRKKVMEAFEQAERKPKPNPNLLFSDVYQEMPTQ
LRKQQESLARHLQTYGEHYPLEHFDK
NT seq
1341 nt
NT seq
+upstream
nt +downstream
nt
atggcggtagcgatcgttgcagcgagggtctggcggccaaaccgtggcctgagccaggct
gccctcctgctgctgctgcggcggcctggggctcgaggactggctagatctcacccccac
aggcagcagcagcagttctcatctctggatgacaagccccagttcccaggggcctcggca
gagtttatagacaagttggaattcatccagcccaacgtcatctctggaatccccatctac
cgcgtcatggaccggcaaggccagatcatcaaccccagcgaggacccccacctgccgaag
gagaaggtgctgaagctctataagagcatgacactgcttaacaccatggaccgcatcctc
tatgagtctcagcggcagggccggatctccttctacatgaccaactatggtgaggagggc
acgcatgtggggagtgctgccgccctggacaacacggacctggtgtttggccagtaccgg
gaggcaggtgtgctgatgtatcgggactaccccctggaactattcatggcccagtgctat
ggcaacatcagtgacttgggcaaggggcgccagatgcccgtccattacggctgcaaggaa
cgccacttcgtcactatctcctctccactggccacgcagatccctcaggcggtgggggcg
gcctacgcagccaagcgggccaacgccaacagggtggtcatctgttactttggcgagggg
gcggccagcgaaggggacgcccatgccggcttcaacttcgctgccacacttgagtgcccc
atcatcttcttctgccggaacaatggctacgccatctccacgcccacctccgagcagtat
cgcggcgatggcattgcagcacgaggccctgggtatggcatcatgtcaatccgcgtggat
ggtaatgatgtgtttgctgtgtacaatgccacaaaggaggcccgacgccgggctgtggca
gagaaccagcccttcctcatcgaggccatgacctacaggattgggcaccacagcaccagt
gacgacagttcagcgtaccgctcggtggacgaggtcaattactgggacaagcaggaccac
cccatctcccggctgcggcactacctgctgagccaaggctggtgggatgaggagcaggag
aaggcctggaggaagcagtcccgcaagaaggtgatggaggcctttgagcaggctgagcgg
aagcccaaacccaaccccaacctgctcttctcagacgtttatcaagagatgcccacccag
ctccgcaagcagcaggagtccctggcccgccacctgcagacctacggggagcactaccca
ctggagcacttcgataagtga
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