Symphalangus syndactylus (siamang): 129470263
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Entry
129470263 CDS
T10134
Symbol
ATP2A3
Name
(RefSeq) sarcoplasmic/endoplasmic reticulum calcium ATPase 3 isoform X1
KO
K05853
P-type Ca2+ transporter type 2A [EC:
7.2.2.10
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn04020
Calcium signaling pathway
ssyn04022
cGMP-PKG signaling pathway
ssyn04024
cAMP signaling pathway
ssyn04148
Efferocytosis
ssyn04260
Cardiac muscle contraction
ssyn04261
Adrenergic signaling in cardiomyocytes
ssyn04380
Osteoclast differentiation
ssyn04919
Thyroid hormone signaling pathway
ssyn04972
Pancreatic secretion
ssyn05010
Alzheimer disease
ssyn05017
Spinocerebellar ataxia
ssyn05022
Pathways of neurodegeneration - multiple diseases
ssyn05410
Hypertrophic cardiomyopathy
ssyn05412
Arrhythmogenic right ventricular cardiomyopathy
ssyn05414
Dilated cardiomyopathy
ssyn05415
Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04020 Calcium signaling pathway
129470263 (ATP2A3)
04024 cAMP signaling pathway
129470263 (ATP2A3)
04022 cGMP-PKG signaling pathway
129470263 (ATP2A3)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
129470263 (ATP2A3)
09150 Organismal Systems
09152 Endocrine system
04919 Thyroid hormone signaling pathway
129470263 (ATP2A3)
09153 Circulatory system
04260 Cardiac muscle contraction
129470263 (ATP2A3)
04261 Adrenergic signaling in cardiomyocytes
129470263 (ATP2A3)
09154 Digestive system
04972 Pancreatic secretion
129470263 (ATP2A3)
09158 Development and regeneration
04380 Osteoclast differentiation
129470263 (ATP2A3)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
129470263 (ATP2A3)
05017 Spinocerebellar ataxia
129470263 (ATP2A3)
05022 Pathways of neurodegeneration - multiple diseases
129470263 (ATP2A3)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
129470263 (ATP2A3)
05412 Arrhythmogenic right ventricular cardiomyopathy
129470263 (ATP2A3)
05414 Dilated cardiomyopathy
129470263 (ATP2A3)
05415 Diabetic cardiomyopathy
129470263 (ATP2A3)
Enzymes [BR:
ssyn01000
]
7. Translocases
7.2 Catalysing the translocation of inorganic cations
7.2.2 Linked to the hydrolysis of a nucleoside triphosphate
7.2.2.10 P-type Ca2+ transporter
129470263 (ATP2A3)
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
Cation_ATPase
Cation_ATPase_C
E1-E2_ATPase
Cation_ATPase_N
Hydrolase
Hydrolase_3
HAD
DUF3106
TNP-like_RNaseH_N
Motif
Other DBs
NCBI-GeneID:
129470263
NCBI-ProteinID:
XP_055113864
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Position
20:64398235..64436592
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AA seq
1100 aa
AA seq
DB search
MEAAHLLSAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDL
LVRILLLAALVSFVLAWFEEGEETTTAFVEPLVIMLILVANAIVGVWQERNAESAIEALK
EYEPEMGKVIRLDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSIL
TGESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNIASGKAVGVAVATGLHTELGKIRSQMA
AVEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAV
ALAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ
MSVCRMFVVAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICALC
NDSALDYNEAKGVYEKVGEATETALTCLVEKMNVFDTDLQALSRVERAGACNAVIKQLMR
KEFTLEFSRDRKSMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSRVRVGSHTAPLTPN
SREQILAKIRDWGSGSDTLRCLALATRDAPPRKEDMELDDCSKFVQYETDLTFVGCVGML
DPPRPEVAACITRCHQAGIRVVMITGDNKGTAVAICRRLGIFGDTEDVAGKAYTGREFDD
LSPEQQRHACRTARCFARVEPAHKSRIVENLQSFNEITAMTGDGVNDAPALKKAEIGIAM
GSGTAVAKSAAEMVLSDDNFASIVAAVEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAI
LGLPEALIPVQLLWVNLVTDGLPATALGFNPPDLDIMEKLPRSPREALISGWLFFRYLAI
GVYVGLATVAAATWWFLYDAEGPHVNFYQLRNFLKCSKDNPLFAGIDCEVFESRFPTTMA
LSVLVTIEMCNALNSVSENQSLLRMPPWMNPWLLAAVAMSMALHFLILLVPPLPLIFQVT
PLSGRQWVVVLQISLPVILLDEALKYLSRNHMHACLYPGILRTVSQAWSRQPLTTSWTPD
HTGARDTASSCCQSCSGREEAGTSSRSWEFVQRQWPYGWTAVQGPRLGWAVAEACIGAAG
SLGATSGRNVPQGRGWRDYK
NT seq
3303 nt
NT seq
+upstream
nt +downstream
nt
atggaggcggcgcacctgctctcggccgccgacgtgctgcgccacttctcggtgacagcc
gagggcggcctgagcccggcgcaggtgaccggcgcgcgggagcgctacggccccaacgag
ctcccgagtgaggaagggaagtccctgtgggagctggtgctggaacagtttgaggacctc
ctggtgcgcatcctgctgctggctgcccttgtctcctttgtcctggcctggttcgaggag
ggcgaggagaccacgaccgccttcgtggagcccctggtcatcatgctgatcctcgtggcc
aatgccattgtgggcgtgtggcaggaacgcaacgccgagagtgccatcgaggccctgaag
gagtatgagcctgagatgggcaaggtgatccgcttggaccgcaagggcgtgcagaggatc
cgtgcccgggacatcgtcccaggggacattgtagaagtggcggtgggggacaaagtgcct
gctgacctccgactcatcgagatcaagtccaccacgctgcgagtggaccagtccatcctg
acgggtgaatctgtgtccgtgaccaagcacacagaggccatcccagaccccagagctgtg
aaccaggacaagaagaacatgctgttttctggcaccaatatcgcatcgggcaaagcagtg
ggtgtggccgtggctaccggcctgcacacagagctgggcaagatccggagccagatggcg
gcagtggagcccgagcggacgccgctgcagcgcaagctagatgagtttggacggcagctg
tcccacgccatctctgtgatctgcgtggccgtgtgggtcatcaacatcggccacttcgct
gacccggcccatggtggctcctggctgcgcggcgctgtctactacttcaagatcgccgtg
gccctggctgtggcggccatccccgagggcctccctgctgtcatcactacatgcctggca
ctgggcacgcggcgcatggcacgcaagaacgccatcgtgcgaagcctgccatccgtggag
accctgggctgcacctcagtcatctgctccgacaagacgggcacgctcaccaccaatcag
atgtctgtctgccggatgttcgtggtagccgaggccgatgcgggctcctgccttttgcac
gagttcaccatctcgggtaccacgtatacccccgagggcgaagtgcggcagggggatcag
cctgtgcgctgcggccagttcgacgggctggtggagctggcgaccatctgcgccctgtgc
aacgactcggcgctggactacaacgaggccaagggtgtgtacgagaaggtgggagaggcc
acggagacagctctgacttgcctggtggagaagatgaacgtgttcgacacggacctgcag
gccctgtcccgggtggagcgagctggcgcctgtaacgcggtcatcaagcagctgatgcgg
aaagagttcaccctggagttctcccgagaccggaagtccatgtctgtgtactgcacgccc
acccgccctcaccctaccggccaaggcagcaagatgtttgtgaagggggctcctgagagc
gtgattgagcgctgcagcagagtccgcgtggggagccacacagcacccctgacccccaac
tccagggagcagatcctggcaaagatccgggattggggctcaggctcagacacgctgcgc
tgcctggcactggccacccgggacgcgcccccaaggaaggaggacatggagctggacgac
tgcagcaagtttgtgcagtatgagacggacctgaccttcgtgggctgcgtgggcatgctg
gacccgccgcggcctgaggtggctgcctgcatcacacgctgccaccaggcgggcatccgc
gtggtcatgatcacgggggataacaaaggcactgccgtggccatctgccgcaggcttggc
atctttggggacacagaagacgtggcgggcaaggcctacacgggccgcgagtttgatgac
ctcagccccgagcagcagcgccatgcctgccgcaccgcccgctgcttcgcccgcgtggag
cccgcacacaagtcccgcatcgtggagaacctgcagtcctttaacgagatcaccgccatg
actggtgatggagtgaacgacgcaccagccctgaagaaagcagagatcggcatcgccatg
ggctcaggcacggccgtggccaagtcggcggcagagatggtgctgtcagatgacaacttt
gcctccatcgtggctgcggtggaggagggccgggccatctacaacaacatgaagcaattc
atccgctacctcatctcctccaatgttggcgaggtcgtctgcatcttcctcacggcaatt
ctgggcctgcccgaagccctgatccctgtgcagctgctctgggtgaacctggtgacagac
ggcctacctgccacggctctgggcttcaacccgccagacctggacatcatggagaagctg
ccccggagcccccgagaagccctcatcagtggctggctcttcttccgatacctggctatc
ggagtgtacgtaggcctggccacagtggctgccgccacctggtggttcctgtatgatgcc
gagggacctcacgtcaacttctaccagctgaggaacttcctgaagtgctccaaagacaac
ccgctctttgccggcatcgactgtgaggtgttcgagtcgcgcttccccaccaccatggcc
ttgtccgtgctcgtgaccattgaaatgtgcaatgccctcaacagcgtctcggagaaccag
tcgctgctgcggatgccgccctggatgaacccctggctgctggcggctgtggccatgtcc
atggccctgcacttcctcatcctgcttgtgccgcccctgcctctcattttccaggtgacc
ccactgagcgggcgccagtgggtggtggtgctccagatatctctgcctgtcatcctgctg
gatgaggccctcaagtacctgtcccggaaccacatgcacgcctgtctttatccaggcatt
ctcaggacagtctcgcaggcctggagtaggcagccgctgaccacctcttggaccccagac
cacaccggggccagggacacagcatcgtcttgctgtcagagctgctcagggagggaggaa
gcagggacaagctcccgttcctgggaatttgtgcagaggcagtggccgtatggctggact
gctgtgcaggggcctaggttaggctgggcagtggctgaggcctgcattggggcagctggg
tcgttgggggccacctctggtaggaatgtgccccagggcagggggtggagggactataaa
tag
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