Symphalangus syndactylus (siamang): 129475487
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Entry
129475487 CDS
T10134
Symbol
PDHA1
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial isoform X3
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00010
Glycolysis / Gluconeogenesis
ssyn00020
Citrate cycle (TCA cycle)
ssyn00620
Pyruvate metabolism
ssyn00785
Lipoic acid metabolism
ssyn01100
Metabolic pathways
ssyn01200
Carbon metabolism
ssyn01210
2-Oxocarboxylic acid metabolism
ssyn04066
HIF-1 signaling pathway
ssyn04922
Glucagon signaling pathway
ssyn05230
Central carbon metabolism in cancer
ssyn05415
Diabetic cardiomyopathy
Module
ssyn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
129475487 (PDHA1)
00020 Citrate cycle (TCA cycle)
129475487 (PDHA1)
00620 Pyruvate metabolism
129475487 (PDHA1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
129475487 (PDHA1)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
129475487 (PDHA1)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
129475487 (PDHA1)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
129475487 (PDHA1)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
129475487 (PDHA1)
Enzymes [BR:
ssyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
129475487 (PDHA1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Motif
Other DBs
NCBI-GeneID:
129475487
NCBI-ProteinID:
XP_055123539
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All DBs
Position
X:33447516..33464280
Genome browser
AA seq
397 aa
AA seq
DB search
MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTRED
GLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINPTDH
LITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPL
GAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSV
ERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHS
MSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFA
TADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
atgaggaagatgctcgccgccgtctcccgcgtgttgtctggcgcttctcagaagccggca
agcagagtgctagtagcatcccgtaattttgcaaatgatgcaacatttgaaattaagaaa
tgtgaccttcaccggctggaagaaggccctcctgtcacaacagtgctcaccagggaggat
gggctcaaatactacaggatgatgcagactgtgcgccgaatggagttgaaagcagatcag
ctgtataaacagaagattattcgtggtttctgtcacttgtgtgatggtcagtttctcctt
cctctaacacaggaagcttgctgtgtgggcctggaggccggcatcaaccccacagaccat
ctcatcacagcctaccgggctcacggctttaccttcacccggggcctttccgtccgagaa
attctcgcagagcttacaggacgaaaaggaggttgtgctaaagggaaaggaggatcgatg
cacatgtatgccaagaacttctacgggggcaatggcatcgtgggagcgcaggtgcccctg
ggcgctgggattgctctagcctgtaagtataatggaaaagatgaggtctgcctgacttta
tatggcgatggtgctgctaaccagggccagatattcgaagcttacaacatggcagctttg
tggaaattaccttgtattttcatctgtgagaataatcgctatggaatgggaacgtctgtt
gagagagcagcagccagcactgattactacaagagaggcgatttcattcctgggctgaga
gtggatggaatggatatcctgtgcgtccgagaggcgacaaggtttgctgctgcctattgt
agatctgggaaggggcccatcctgatggagctgcagacttaccgttaccacggacacagt
atgagtgatcctggagtcagttaccgtacacgagaagaaattcaggaagtaagaagtaag
agtgaccctattatgcttctcaaggacaggatggtgaacagcaatcttgccagtgtggaa
gaactaaaggaaattgatgtggaagtgaggaaggagattgaggatgctgcccagtttgcc
acggccgatcctgagccacctttggaagagctgggctaccacatctactccagcgaccca
ccttttgaagttcgtggtgccaatcagtggatcaagtttaagtcagtcagttaa
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