Symphalangus syndactylus (siamang): 129478361
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Entry
129478361 CDS
T10134
Symbol
RPS6KB2
Name
(RefSeq) ribosomal protein S6 kinase beta-2 isoform X1
KO
K04688
ribosomal protein S6 kinase beta [EC:
2.7.11.1
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn01521
EGFR tyrosine kinase inhibitor resistance
ssyn01522
Endocrine resistance
ssyn04012
ErbB signaling pathway
ssyn04066
HIF-1 signaling pathway
ssyn04140
Autophagy - animal
ssyn04150
mTOR signaling pathway
ssyn04151
PI3K-Akt signaling pathway
ssyn04152
AMPK signaling pathway
ssyn04211
Longevity regulating pathway
ssyn04213
Longevity regulating pathway - multiple species
ssyn04350
TGF-beta signaling pathway
ssyn04371
Apelin signaling pathway
ssyn04666
Fc gamma R-mediated phagocytosis
ssyn04714
Thermogenesis
ssyn04910
Insulin signaling pathway
ssyn04931
Insulin resistance
ssyn05163
Human cytomegalovirus infection
ssyn05165
Human papillomavirus infection
ssyn05170
Human immunodeficiency virus 1 infection
ssyn05200
Pathways in cancer
ssyn05205
Proteoglycans in cancer
ssyn05207
Chemical carcinogenesis - receptor activation
ssyn05210
Colorectal cancer
ssyn05212
Pancreatic cancer
ssyn05221
Acute myeloid leukemia
ssyn05224
Breast cancer
ssyn05225
Hepatocellular carcinoma
ssyn05226
Gastric cancer
ssyn05231
Choline metabolism in cancer
ssyn05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
129478361 (RPS6KB2)
04350 TGF-beta signaling pathway
129478361 (RPS6KB2)
04371 Apelin signaling pathway
129478361 (RPS6KB2)
04066 HIF-1 signaling pathway
129478361 (RPS6KB2)
04151 PI3K-Akt signaling pathway
129478361 (RPS6KB2)
04152 AMPK signaling pathway
129478361 (RPS6KB2)
04150 mTOR signaling pathway
129478361 (RPS6KB2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
129478361 (RPS6KB2)
09150 Organismal Systems
09151 Immune system
04666 Fc gamma R-mediated phagocytosis
129478361 (RPS6KB2)
09152 Endocrine system
04910 Insulin signaling pathway
129478361 (RPS6KB2)
09149 Aging
04211 Longevity regulating pathway
129478361 (RPS6KB2)
04213 Longevity regulating pathway - multiple species
129478361 (RPS6KB2)
09159 Environmental adaptation
04714 Thermogenesis
129478361 (RPS6KB2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129478361 (RPS6KB2)
05205 Proteoglycans in cancer
129478361 (RPS6KB2)
05207 Chemical carcinogenesis - receptor activation
129478361 (RPS6KB2)
05231 Choline metabolism in cancer
129478361 (RPS6KB2)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
129478361 (RPS6KB2)
09162 Cancer: specific types
05210 Colorectal cancer
129478361 (RPS6KB2)
05212 Pancreatic cancer
129478361 (RPS6KB2)
05225 Hepatocellular carcinoma
129478361 (RPS6KB2)
05226 Gastric cancer
129478361 (RPS6KB2)
05221 Acute myeloid leukemia
129478361 (RPS6KB2)
05224 Breast cancer
129478361 (RPS6KB2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
129478361 (RPS6KB2)
05163 Human cytomegalovirus infection
129478361 (RPS6KB2)
05165 Human papillomavirus infection
129478361 (RPS6KB2)
09167 Endocrine and metabolic disease
04931 Insulin resistance
129478361 (RPS6KB2)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129478361 (RPS6KB2)
01522 Endocrine resistance
129478361 (RPS6KB2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssyn01001
]
129478361 (RPS6KB2)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
129478361 (RPS6KB2)
Protein kinases [BR:
ssyn01001
]
Serine/threonine kinases: AGC group
RSK family [OT]
129478361 (RPS6KB2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
Pkinase_C
Kinase-like
Pkinase_fungal
ABC1
Seadorna_VP7
Motif
Other DBs
NCBI-GeneID:
129478361
NCBI-ProteinID:
XP_055125945
LinkDB
All DBs
Position
1:96238846..96259394
Genome browser
AA seq
508 aa
AA seq
DB search
MAAVFDLDLETEEGSEGEGEPELSPADVCPLAELRAAGLEPVGHYEEVELTETNVNLGPE
RIGPHCFELLRVLGKGGYGKVFQVRKVQGTNLGKIYAMKVLRKAKIVRNAKDTAHTRAER
NILESVKHPFIVELAYAFQTGGKLYLILECLSGGELFTHLEREGIFLEDTACFYLAEITL
ALGHLHSQGIIYRDLKPENIMLSSQGHIKLTDFGLCKESIHEGAVTHTFCGTIEYMAPEI
LVRSGHNRAVDWWSLGALMYDMLTGSPPFTAENRKKTMDKIIKGKLALPPYLTPDARDLV
KKFLKRNPSQRIGGGPGDAADVQRHPFFRHMNWDDLLAWRVDPPFRPCLQSEEDVSQFDT
RFTRQTPVDSPDDTALSESANQAFLGFTYVAPSVLDSIKEGFSFQPKLRSPRRLNSSPRA
PIRPHGDLLWAGYLSTSLLAFPRVSLQATIRDVVIVCILLILLSLKVIVWGPQLSSGLQP
ATWGAGPEQAPCAAPQRGTQAGRVVVAP
NT seq
1527 nt
NT seq
+upstream
nt +downstream
nt
atggcggccgtgtttgatttggatttggagacggaggaaggcagcgagggcgagggcgag
ccagagctcagccccgcggacgtgtgtccccttgctgagttgagggcagctggcctagag
cctgtgggacactacgaagaggtggagctgactgagaccaacgtgaaccttggcccagag
cgcatcgggccccactgctttgagctgcttcgtgtgctgggcaaggggggctatggcaag
gtgttccaggtgcgaaaggtgcaaggcaccaacttgggcaaaatatatgccatgaaagtc
ctaaggaaggccaaaattgtgcgcaacgccaaggacacagcacacacacgggctgagcgg
aacattctagagtcagtgaagcacccctttattgtggaactggcctatgccttccagact
ggtggcaaactctacctcatccttgagtgtctcagtggtggcgagctcttcacgcatctg
gagcgagagggcatcttcctggaagatacggcttgcttctacctggcggagatcacgctg
gccctgggccatctccactcgcagggcatcatctaccgggacctcaagcccgagaacatc
atgctcagcagccagggccacatcaaactgaccgactttggactctgcaaggagtcgatc
catgagggtgccgtcactcacaccttctgcggcaccattgagtacatggcccctgagatt
ctggtgcgcagtggccacaaccgggctgtggactggtggagcctgggggccctgatgtac
gacatgctcactggatcgccgcccttcactgcagagaaccggaagaaaaccatggataag
atcatcaagggcaagctggcgctgcccccctacctcaccccagatgcccgggaccttgtc
aaaaagtttctgaaacggaatcccagccagcggattgggggtggcccaggggatgctgct
gatgtgcagagacatccctttttccggcacatgaattgggacgaccttctggcctggcgt
gttgacccccctttcaggccctgtctgcagtcagaggaggacgtgagccagtttgatacc
cgcttcacacggcagacgccggtggacagtcccgatgacacggccctcagcgagagtgcc
aaccaggccttcctaggcttcacgtacgtggcgccgtctgtcctggacagcatcaaggag
ggcttctccttccagcccaagctgcgctcacccaggcgcctcaacagtagcccccgggcc
cccatcaggccgcatggggacctgctctgggctggatacctctccacatcgctgctcgcc
ttccccagggtcagcctgcaggccaccatccgcgacgttgtcatagtctgcatcctgctc
atcctcctgtcgctcaaggtcattgtctggggaccccagctcagctcgggcctgcagcca
gcgacctggggggctggcccagagcaggcgccgtgtgcggccccacagcgcggcacccag
gcgggccgggtggtagtagccccctga
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