KEGG   Symphalangus syndactylus (siamang): 129478677
Entry
129478677         CDS       T10134                                 
Symbol
NOTCH1
Name
(RefSeq) neurogenic locus notch homolog protein 1 isoform X1
  KO
K02599  Notch 1
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn01522  Endocrine resistance
ssyn04330  Notch signaling pathway
ssyn04658  Th1 and Th2 cell differentiation
ssyn04919  Thyroid hormone signaling pathway
ssyn05020  Prion disease
ssyn05165  Human papillomavirus infection
ssyn05200  Pathways in cancer
ssyn05206  MicroRNAs in cancer
ssyn05224  Breast cancer
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04330 Notch signaling pathway
    129478677 (NOTCH1)
 09150 Organismal Systems
  09151 Immune system
   04658 Th1 and Th2 cell differentiation
    129478677 (NOTCH1)
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    129478677 (NOTCH1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    129478677 (NOTCH1)
   05206 MicroRNAs in cancer
    129478677 (NOTCH1)
  09162 Cancer: specific types
   05224 Breast cancer
    129478677 (NOTCH1)
  09172 Infectious disease: viral
   05165 Human papillomavirus infection
    129478677 (NOTCH1)
  09164 Neurodegenerative disease
   05020 Prion disease
    129478677 (NOTCH1)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    129478677 (NOTCH1)
SSDB
Motif
Pfam: EGF hEGF EGF_TEN EGF_CA EGF_2 Ank_2 Ank NOD Notch NODP Ank_4 Ank_5 Ank_3 EGF_3 EGF_DL_JAG
Other DBs
NCBI-GeneID: 129478677
NCBI-ProteinID: XP_055126324
LinkDB
Position
3:8282206..8334214
AA seq 2556 aa
MPPLLAPLLCLALLPALAVRGPRCSQPGETCLNGGKCEAANGTEACVCGGAFVGPRCQDP
NPCLSTPCKNAGTCHVVDRGGVADYACSCPLGFSGPLCLTPLDNACLTNPCRNGGTCDLL
TLTEYKCRCPPGWSGKSCQQADPCASNPCANGGQCLPFEASYICHCPPSFHGPTCRQDVN
ECGQNPGLCRHGGTCHNEVGSYRCVCRATHTGPNCERPYVPCSPSPCQNGGTCRPTGDVT
HECACLPGFTGQNCEENIDDCPGNNCKNGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQ
LMPNACQNGGTCHNTHGGYNCVCVNGWTGEDCSENIDDCASAACFHGATCHDRVASFYCE
CPHGRTGLLCHLNDACISNPCNEGSNCDTNPVNGKAICTCPSGYTGPACSQDVDECSLGA
NPCEHAGKCINTLGSFECQCLQGYTGPRCEIDVNECVSNPCQNDATCLDQIGEFQCICMP
GYEGVHCEVNTDECASSPCLHNGRCLDKINEFQCECPTGFTGHLCQYDVDECASTPCKNG
AKCLDGPNTYTCVCTEGYTGTHCEVDIDECDPDPCHYGSCKDGVATFTCLCRPGYTGHHC
ETNINECSSQPCRHGGTCQDRDNAYLCFCLKGTTGPNCEINLDDCASSPCDSGTCLDKID
GYECACEPGYTGSMCNINIDECAGNPCHNGGTCEDGINGFTCRCPEGYHDPTCLSEVNEC
NSNPCVHGACRDSLNGYKCNCDPGWSGTNCDINNNECESNPCVNGGTCKDMTSGYVCTCR
EGFSGPNCQTNINECASNPCLNQGTCIDDVAGYKCNCLLPYTGATCEVVLAPCAPSPCRN
GGECRGSEDYESFSCVCPTGWQGQTCEVDINECVLSPCRHGASCQNTHGGYRCHCQAGYS
GRNCETDIDDCRPNPCHNGGSCTDGINTAFCDCLPGFQGTFCEEDINECASDPCHNGANC
TDCVDSYTCTCPAGFSGIHCENNTPDCTESSCFNGGTCMDGINSFTCLCPPGFTGSYCQH
DVNECDSQPCLHGGTCQDGCGSYRCTCPQGYTGPNCQNLVHWCDSSPCKNGGKCWQTHTQ
YRCECPSGWTGLYCDVPSVSCEVAAQRQGVDVARLCQHGGLCVDAGNTHHCRCQAGYTGS
YCEDLVDECSPSPCQNGATCTDYLGGYSCKCVAGYHGVNCSEEIDECLSHPCQNGGTCLD
LPNTYKCSCPRGTQGVHCEINVDDCNPLVDPVSRSPKCFNNGTCVDQVGGYSCTCPPGFV
GERCEGDVNECLSNPCDARGTQNCVQRVNDFHCECRAGHTGRRCESVINGCKGKPCKNGG
TCAVASNTARGFICKCPAGFEGATCENDARTCGSLRCLNGGTCISGPRSPTCLCLGPFTG
PECQFPASSPCLGGNPCYNQGTCEPTSESPFYRCLCPAKFNGLLCHILDYSFGGGAGRDI
PPPQIEEACELPECQEDAGNKVCSLQCNNHACGWDGGDCSLNFNDPWKNCTQSLQCWKYF
SDGHCDSQCNSAGCLFDGFDCQRAEGQCNPLYDQYCKDHFSDGHCDQGCNSAECEWDGLD
CAEHVPERLAAGTLVVVVLMPPEQLRNSSFHFLRELSRVLHTNVVFKRDAHGQQMIFPYY
GREEELRKHPIKRAAEGWAAPDALLGQVKASLLPGGSRGGRRRRELDPMDVRGSIVYLEI
DNRQCVQASSQCFQSATDVAAFLGALASLGSLNIPYKIEAVQSETVEPPPPAQLHFMYVA
AAAFVLLFFVGCGVLLSRKRRRQHGQLWFPEGFKVSEASKKKRREPLGEDSVGLKPLKNA
SDGALMDDNQNEWGDEDLETKKFRFEEPVVLPDLDDQTDHRQWTQQHLDAADLRMSAMAP
TPPQGEVDADCMDVNVRGPDGFTPLMIASCSGGGLETGNSEEEEDAPAVISDFIYQGASL
HNQTDRTGETALHLAARYSRSDAAKRLLEASADANIQDNMGRTPLHAAVSADAQGVFQIL
IRNRATDLDARMHDGTTPLILAARLAVEGMLEDLINSHADVNAVDDLGKSALHWAAAVNN
VDAAVVLLKNGANKDMQNNKEETPLFLAAREGSYETAKVLLDHFANRDITDHMDRLPRDI
AQERMHHDIVRLLDEYNLVRSPQLHGAPLGGTPTLSPPLCSPNGYLGSLKPGVQGKKVRK
PSSKGLACGSKEAKDLKARRKKAQDGKGCLLDSSGMLSPVDSLESPHGYLSDVASPPLLP
SPFQQSPSVPLNHLPGMPDTHLGIGHLNVAAKPEMAALGGGGRLAFETGPPRLSHLPVAS
GTSTVLGSSSGGAVNFTVGGSTSLNGQCEWLSRLQSGMVPNQYNPLRGSVAPGPLSTQAP
SLQHGMVGPLHSSLAASALSQMMSYQGLPSTRLATQPHLVQTQQVQPQNLQMQQQNLQPP
NIQQQQSLQPPPPPPQPHLGVSSAASSHLGRSFLGGDPSQADVQPLGPSSLAVHTILPQE
SPALPTSLPSSLVPPVTAAQFLTPPSQHSYSSSPVDNTPSHQLQVPEHPFLTPSPESPDQ
WSSSSPHSNVSDWSEGVSSPPTSMQSQIARIPEAFK
NT seq 7671 nt   +upstreamnt  +downstreamnt
atgccgccgctcctggcgcccctgctctgcctggcgctgctgcccgcgctcgccgtacga
ggcccgcgatgctcccagcccggtgagacctgcctgaatggcgggaagtgtgaagcggcc
aatggcacggaggcctgcgtctgtggtggggccttcgtgggcccgcgatgccaggacccc
aacccgtgcctcagcaccccctgcaagaacgctgggacatgccacgtggtggaccgcgga
ggcgtggcagactatgcctgcagctgtcccctgggcttctctgggcccctctgcctgaca
cccctggacaacgcctgcctcaccaacccctgccgcaatgggggcacctgcgacctgctc
acgctgacggagtacaagtgccgctgccctcctggctggtcagggaaatcgtgccagcag
gctgacccgtgtgcctccaacccttgcgccaacggtggccaatgcctgcccttcgaggcc
tcctacatctgccactgcccacccagcttccacggccccacctgccggcaggatgtcaac
gagtgcggccagaaccccgggctttgccgccacggaggcacctgccacaacgaggtcggc
tcctaccgctgcgtctgccgcgccacccacaccggccccaactgcgagcggccctacgtg
ccctgcagcccctcgccctgccagaacgggggcacctgccgccccacgggtgacgtcacc
catgagtgtgcctgcctgccaggcttcaccggccagaactgtgaggagaatatcgacgat
tgtccaggaaacaactgcaagaacgggggcgcctgtgtggacggtgtgaacacctacaac
tgccgctgcccgccagagtggacaggtcagtactgtaccgaggatgtggacgagtgccag
ctgatgccaaatgcctgccagaacggcgggacctgccacaacacccacggtggctacaac
tgcgtgtgtgtcaacggctggactggtgaggactgcagcgagaacatcgatgactgtgcc
agcgccgcctgcttccacggcgccacctgccatgaccgcgtggcctccttctactgcgag
tgtccccatggccgcacaggtctgctgtgccacctcaacgacgcgtgcatcagcaacccc
tgcaatgagggctccaactgtgacaccaaccccgtcaatggcaaggccatctgcacctgc
ccctcggggtacacgggcccggcctgcagccaggacgtggatgagtgctcgctgggtgcc
aacccctgcgagcatgcgggcaagtgcatcaacacgctgggctcctttgagtgccagtgt
ctgcagggctacacaggcccccgctgcgagatcgacgtcaacgagtgtgtctcgaacccg
tgccagaacgacgccacctgcctggaccagattggggagttccagtgcatctgcatgccc
ggctacgagggtgtgcactgcgaggtcaacacggacgagtgtgccagcagcccctgcctg
cacaatggccgctgcctggacaagatcaatgagttccagtgcgagtgccccacgggcttc
actgggcatctgtgccagtacgatgtggacgagtgtgccagcaccccctgcaagaatggt
gccaagtgcctggacggacccaacacttacacctgtgtgtgcacagaagggtacacaggg
acgcactgcgaggtggacattgatgagtgtgaccccgacccctgccactacggctcctgc
aaggacggcgtcgccaccttcacctgcctctgccgcccgggctacacgggccaccactgc
gagaccaacatcaacgagtgctctagccagccctgccgccacgggggcacctgccaggac
cgtgacaatgcctacctctgcttctgcctgaaggggaccacaggacccaactgcgagatc
aacctggatgactgtgccagcagcccctgcgactcgggcacctgtctggacaagatcgat
ggctacgagtgtgcctgtgagccgggctacacagggagcatgtgtaacatcaacatcgat
gagtgtgcgggcaacccctgccacaacgggggcacctgtgaggacggcatcaatggcttc
acctgccgctgccccgagggctaccacgaccccacctgcctgtctgaggtcaatgagtgc
aacagcaacccctgcgtccatggggcctgccgggacagcctcaacgggtacaagtgcaac
tgtgaccctgggtggagtgggaccaactgtgacatcaacaacaacgagtgtgagtccaac
ccttgtgtcaacggcggcacctgcaaagacatgaccagtggctatgtgtgcacctgccgg
gagggcttcagcggtcccaactgccagaccaacatcaacgagtgtgcatccaacccatgt
ctgaaccagggcacgtgtattgacgacgttgctgggtacaagtgcaactgcctgctgccc
tacacaggtgccacatgtgaggtggtgctggccccatgtgcccccagcccctgcagaaat
ggcggagagtgcaggggatccgaggactatgagagcttctcctgcgtctgccccacgggc
tggcaagggcagacctgtgaggtcgacatcaacgagtgtgttctgagcccgtgccgacat
ggcgcatcctgccagaacacccatggcggctaccgctgccactgccaggccggctacagc
gggcgcaactgcgagacggacatcgacgactgccggcccaacccgtgtcacaacggcggc
tcctgcacagatggcatcaacacggccttctgcgactgcctgcccggcttccagggcact
ttctgtgaggaggacatcaacgagtgtgccagtgacccctgccacaacggggccaactgc
acggactgcgtggacagctacacgtgcacctgccccgcaggcttcagcgggatccactgt
gagaacaacacgcccgactgcacagagagctcctgcttcaacggtggcacctgcatggat
ggcatcaactcgttcacctgcctgtgtccacccggcttcacgggcagctactgccagcac
gatgtcaacgagtgcgactcacagccctgcctgcacggtggcacctgccaggacggctgc
ggctcctacagatgcacctgcccccagggctacaccggccccaactgccagaacctcgtg
cactggtgtgactcctcgccctgcaagaacggcggcaaatgctggcagacccacacccag
taccgctgcgagtgccccagcggctggaccggcctttactgtgacgtgcccagcgtgtcc
tgtgaggtggctgcgcagcgacaaggtgttgacgttgcccgcctgtgccagcatggaggg
ctctgtgtggacgcgggcaacacgcaccactgccgctgccaggcgggctacacaggcagc
tactgtgaggacctggtggacgagtgctcacccagcccctgccagaatggggccacctgc
acggactacctgggtggctactcctgcaagtgcgtggccggctaccacggggtgaactgc
tctgaggagatcgacgagtgcctgtcccacccctgccagaacgggggcacctgcctcgac
ctccccaacacctacaagtgctcctgcccacggggcacacagggtgtgcactgtgagatc
aacgtggacgactgcaaccccctcgttgaccccgtgtcccggagccccaagtgctttaac
aacggcacctgtgtggaccaggtgggcggctacagctgcacctgcccgccgggcttcgtg
ggcgagcgctgtgagggggatgtcaacgagtgcctgtccaacccctgcgacgcccgtggc
acccagaactgcgtgcagcgcgtcaacgacttccactgcgagtgccgtgccggtcacacc
gggcgccgctgtgagtccgtcatcaacggctgcaagggcaagccctgcaagaatgggggc
acctgcgccgtggcctccaacaccgcccgcgggttcatctgcaagtgccctgcgggcttc
gagggcgccacgtgtgagaatgacgctcgtacctgcggcagcctgcgctgcctcaatggt
ggcacatgcatctccggcccgcgcagccccacctgcctgtgcctgggccccttcacaggc
cccgaatgccagttcccggccagtagcccctgcctgggcggcaacccctgctacaaccag
gggacctgtgagcccacgtccgagagccccttctaccgttgcctgtgccccgccaaattc
aacgggctcttgtgccacatcctggactacagcttcgggggtggggccgggcgcgacatc
cccccgccgcagatcgaggaggcgtgcgagctgcccgagtgccaggaggacgcgggcaac
aaggtctgcagcctgcagtgcaacaaccacgcgtgcggctgggacggtggcgattgctcc
ctcaacttcaatgacccctggaagaactgcacacagtctctgcagtgctggaagtacttc
agcgacggccactgtgacagccagtgcaactcggccggctgcctcttcgacggcttcgac
tgccagcgcgcggaaggccagtgcaaccccctgtacgaccagtactgcaaggaccacttc
agcgatgggcactgcgaccagggctgcaacagcgcggagtgcgagtgggacgggctggat
tgtgcagagcatgtgcccgagaggctggcagccggcacgctggtggtggtggtgctgatg
ccgccggagcagctgcgcaatagctccttccacttcctgcgggagctcagccgcgtgctg
cacaccaacgtggtcttcaagcgcgacgcacacggccagcagatgatcttcccctactac
ggccgcgaggaggagctgcgcaagcaccccatcaagcgtgccgccgagggctgggccgca
cccgatgccctgctgggccaggtgaaggcctcgctgctccctggtggcagcaggggtggg
cggcggcggagggagctggaccccatggacgtccgcggctccatcgtctacctggagatt
gacaaccggcagtgtgtgcaggcctcctcgcagtgcttccagagtgccaccgacgtggcc
gcgttcctgggagcgctcgcctcgctgggcagcctcaacatcccctacaagattgaggct
gtgcagagtgagaccgtggagccgcccccgccggcgcagctgcacttcatgtacgtggcg
gcggccgcctttgtgctcctgttcttcgtgggctgcggggtactgctgtcccgcaagcgt
cggcggcagcatggccaactctggttccctgagggcttcaaagtgtccgaggccagcaag
aagaagcggcgggagcccctcggcgaggactccgtgggcctcaagcccctgaagaacgcc
tcagacggtgccctcatggacgacaaccagaatgagtggggggacgaggacctggagacc
aagaagttccggttcgaggagcccgtggttctgcctgacctggacgaccagacagaccac
cggcagtggactcagcagcacctggatgccgctgacctgcgcatgtctgccatggccccc
acaccgccccagggcgaggttgacgccgactgcatggacgtcaatgtccgcgggcctgac
ggctttaccccgctcatgatcgcctcctgcagcgggggcggcctggagacgggcaacagc
gaggaggaggaggatgcgccggccgtcatctccgacttcatctaccagggcgccagcctg
cacaaccagacggaccgcacgggcgagactgccttgcacctggccgcccgctactcacgc
tctgatgccgccaagcgcctgctggaggccagcgcagacgccaacatccaggacaacatg
ggccgcaccccgctgcatgcggctgtgtctgccgacgcacaaggtgtcttccagatcctg
atccggaaccgagccacagacttggatgcccgcatgcatgatggcacgactccgctgatc
ctggctgcccgcctggccgtggagggcatgctggaggacctcatcaactcacacgccgac
gtcaacgctgtagatgacctgggcaagtccgccctgcactgggccgccgccgtgaacaat
gtggatgccgcagttgtgctcctgaagaacggggctaacaaagacatgcagaacaacaag
gaggagacgcccctgtttctggccgcccgggagggcagctacgagactgccaaggtgctg
ctggaccactttgccaaccgggacatcacggatcatatggaccgcctgccgcgggacatc
gcgcaggagcgtatgcaccacgacatcgtgagactgctggacgaatacaacctggtgcgc
agcccgcagctgcacggagccccgctggggggcacgcccaccctgtcgcccccgctctgc
tcgcccaacggctacctgggcagcctcaagcccggcgtgcagggcaagaaggttcgcaag
cccagcagcaaaggcctggcctgtggaagcaaggaggccaaggacctcaaggcgcggagg
aagaaggcccaggacggcaagggctgcctgctggacagttccggcatgctctcgcccgtg
gactccctggagtcaccccacggctacctgtcagacgtggcctcgccgccactgctgccc
tccccgtttcagcagtctccgtccgtgccccttaaccacctgcctggtatgcccgacacc
cacctgggcatcgggcacctgaacgtggcggccaagcccgagatggcggcgctgggtggg
ggcggccggctggccttcgagaccggcccccctcgtctctcccacctgcccgtggcctct
ggcaccagcaccgtcctgggctccagcagcggaggggccgtgaatttcaccgtgggcggg
tccaccagtttgaatggtcaatgcgagtggctgtcccggctgcagagcggcatggtgccg
aaccaatacaaccctctgcgggggagcgtggcaccaggccccctgagcacgcaggccccc
tccctgcagcacggcatggtgggcccgctgcacagtagccttgctgccagcgccctgtcc
caaatgatgagctaccagggcctgcccagcacccggctggccacccagcctcacctggtg
cagacccagcaggtgcagccacaaaacttacagatgcagcagcagaacctgcagccacca
aacatccagcagcagcaaagcctgcagccaccaccaccaccaccacagccacaccttggc
gtgagctcagcagccagtagccacctgggccggagcttcctgggtggagacccgagccag
gcagacgtgcagccactgggccccagcagcctggcggtgcacactattctgccccaggag
agccccgccctgcccacatcgctgccatcctcactggtcccgcctgtgaccgcagcccag
ttcctgacgcccccctcgcagcacagctactcctcctcgcctgtggacaacacccccagc
caccagctacaggtgcctgagcaccccttcctcaccccgtcccccgagtcccctgaccag
tggtccagctcgtccccgcattccaacgtctccgactggtccgagggcgtctccagccct
cccaccagcatgcagtcccagatcgcccgcattccggaggccttcaagtaa

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