Symphalangus syndactylus (siamang): 129478959 Help Entry 129478959         CDS       T10134                                  Symbol TLR4 Name (RefSeq) toll-like receptor 4 isoform X1   KO K10160   toll-like receptor 4 Organism ssyn  Symphalangus syndactylus (siamang) Pathway ssyn04064   NF-kappa B signaling pathway ssyn04066   HIF-1 signaling pathway ssyn04145   Phagosome ssyn04151   PI3K-Akt signaling pathway ssyn04217   Necroptosis ssyn04613   Neutrophil extracellular trap formation ssyn04620   Toll-like receptor signaling pathway ssyn04621   NOD-like receptor signaling pathway ssyn04936   Alcoholic liver disease ssyn05132   Salmonella infection ssyn05133   Pertussis ssyn05134   Legionellosis ssyn05135   Yersinia infection ssyn05140   Leishmaniasis ssyn05142   Chagas disease ssyn05144   Malaria ssyn05145   Toxoplasmosis ssyn05146   Amoebiasis ssyn05152   Tuberculosis ssyn05161   Hepatitis B ssyn05162   Measles ssyn05164   Influenza A ssyn05170   Human immunodeficiency virus 1 infection ssyn05171   Coronavirus disease - COVID-19 ssyn05205   Proteoglycans in cancer ssyn05235   PD-L1 expression and PD-1 checkpoint pathway in cancer ssyn05321   Inflammatory bowel disease ssyn05323   Rheumatoid arthritis ssyn05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:ssyn00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     129478959 (TLR4)    04066 HIF-1 signaling pathway     129478959 (TLR4)    04151 PI3K-Akt signaling pathway     129478959 (TLR4)  09140 Cellular Processes   09141 Transport and catabolism    04145 Phagosome     129478959 (TLR4)   09143 Cell growth and death    04217 Necroptosis     129478959 (TLR4)  09150 Organismal Systems   09151 Immune system    04613 Neutrophil extracellular trap formation     129478959 (TLR4)    04620 Toll-like receptor signaling pathway     129478959 (TLR4)    04621 NOD-like receptor signaling pathway     129478959 (TLR4)  09160 Human Diseases   09161 Cancer: overview    05205 Proteoglycans in cancer     129478959 (TLR4)    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     129478959 (TLR4)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     129478959 (TLR4)    05161 Hepatitis B     129478959 (TLR4)    05171 Coronavirus disease - COVID-19     129478959 (TLR4)    05164 Influenza A     129478959 (TLR4)    05162 Measles     129478959 (TLR4)   09171 Infectious disease: bacterial    05132 Salmonella infection     129478959 (TLR4)    05135 Yersinia infection     129478959 (TLR4)    05133 Pertussis     129478959 (TLR4)    05134 Legionellosis     129478959 (TLR4)    05152 Tuberculosis     129478959 (TLR4)   09174 Infectious disease: parasitic    05146 Amoebiasis     129478959 (TLR4)    05144 Malaria     129478959 (TLR4)    05145 Toxoplasmosis     129478959 (TLR4)    05140 Leishmaniasis     129478959 (TLR4)    05142 Chagas disease     129478959 (TLR4)   09163 Immune disease    05323 Rheumatoid arthritis     129478959 (TLR4)    05321 Inflammatory bowel disease     129478959 (TLR4)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     129478959 (TLR4)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     129478959 (TLR4)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    04131 Membrane trafficking [BR:ssyn04131]     129478959 (TLR4)   09183 Protein families: signaling and cellular processes    04054 Pattern recognition receptors [BR:ssyn04054]     129478959 (TLR4)    04090 CD molecules [BR:ssyn04090]     129478959 (TLR4)    00536 Glycosaminoglycan binding proteins [BR:ssyn00536]     129478959 (TLR4) Membrane trafficking [BR:ssyn04131]  Endocytosis   Phagocytosis    Toll-like receptors     129478959 (TLR4) Pattern recognition receptors [BR:ssyn04054]  Membrane-bound pattern recognition receptors   Toll-like receptors    129478959 (TLR4) CD molecules [BR:ssyn04090]  Proteins   129478959 (TLR4) Glycosaminoglycan binding proteins [BR:ssyn00536]  Hyaluronan   Cell surface receptors    129478959 (TLR4) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  LRR_8 TIR LRR_4 LRR_14 LRR_1 TIR_2 LRR_9 LRR_5 LRR_Zer-1 LRR_6 LRR_EndoS LRR_R13L1-DRL21 ThsB_TIR Curto_V2 Pentapeptide_4 Motif Other DBs NCBI-GeneID:  129478959 NCBI-ProteinID:  XP_055127282 LinkDB All DBs Position 3:complement(27259175..27272446) Genome browser AA seq 832 aa AA seqDB search MMSALRLAGTLIPAMAFLSCVRPESWDPCVEVVPNITYQCMELNFYKIPDNLPFSTKNLD LSFNPLRHLGSYSFFNFPELQVLDLSRCEIQTIEDGAYQSLSLLSTLILTGNPIQSLALG AFSGLSSLQKLVAVETNLASLENFPIGHLKTLKELNVAHNLIQSFKLPEYFSNLTNLEYL DLSSNKIQSIYCKDLQVLHQMPLLNLSLDLSLNPMNFIQPGAFKEISLHKLTLRNNFDSL NVMKTCIQGLAGLEVHRLVLGEFRNEGNLEEFDKSALEGLCNLTIEEFRLAYLDHYLDDI IDLFNCLANVSSFSLVSVTIKRVEDFSYNFGWQHLELVNCKFGQFPTLNLKSLKRLTFTA NRGGNAFSEVDLPSLEFLDLSRNGLSFKGCCSQSDFGTNSLKYLDLSFNDVITMSSNFLG LEQLEHLDLQHSNLKQMSEFSVFLSLRNLIYLDISHTHTRVAFNGIFNGLSNLEVLKMAG NSFQENFLPDIFTELRNLTFLDLSQCRLEQLSPTAFNSLSSLQVLNMSHNNFFSLDTFPY KCLNSLQVLDYSLNHIMTSKKQELQHFPSSLAFLNLTQNDFACTCEHESFLQWIKDQRQL LVEVERMECATPSDKQGMPVLSLNITCQMNKTIIGVSVLSVLVVSVVAVLVYKFYFHLML LAGCIKYGRGENTYDAFVIYSSQDEDWVRNELVKNLEEGVPPFQLCLHYRDFIPGVAIAA NIIHEGFHKSRKVIVVVSQHFIQSRWCIFEYEIAQTWQFLSSRAGIIFIVLQKVEKTLLR QQVELYRLLSRNTYLEWEDSVLGRHIFWRRLRKALLDGKSWNPEGTVGTGCN NT seq 2499 nt NT seq  +upstreamnt  +downstreamnt atgatgtctgccttgcgcctggctgggactctgatcccagccatggccttcctctcctgc gtgagaccagaaagctgggatccctgcgtggaggtggttcctaacattacttatcaatgc atggagctgaatttctacaaaatcccggacaacctccccttctcaaccaagaacctggac ctgagctttaatcccctgaggcatttaggcagctatagcttcttcaatttcccagaactg caggtgctggatttatccaggtgtgaaatccagacaattgaagatggggcatatcagagc ctaagcctcctctccaccttaatattgacaggaaaccccatccagagtttagctctggga gccttttctggactatcaagtttacagaagctagtggctgtggagacaaatctagcatct ctagagaacttccccattggacatctcaaaactttgaaagaacttaatgtggctcacaat cttatccagtctttcaaattacctgagtatttttctaatctgaccaatctagagtacttg gacctttccagcaacaagattcaaagtatttattgcaaagacttgcaggttctacatcaa atgcccctactcaatctctctttagacctgtccctgaaccctatgaactttatccaacca ggtgcatttaaagaaattagccttcataagctgactttaagaaataattttgatagttta aatgtaatgaaaacttgtattcaaggtctggctggtttagaagtccatcgtttggttctg ggagaatttagaaatgaaggaaacttggaagagtttgacaaatctgctctagagggcctg tgcaatttgaccattgaagaattccgattagcatacttagaccactacctcgatgatatt attgacttatttaattgtttggcaaatgtttcttcattttccctggtgagtgtgactatt aaaagggtagaagacttttcttataatttcggatggcaacatttagaattagttaactgt aaatttggacagtttcccacattgaacctcaaatctctcaaaaggcttactttcactgcc aacagaggtgggaatgctttttcagaagttgatctaccaagccttgagtttctagatctc agtagaaatggcttgagtttcaaaggttgctgttctcaaagtgattttgggacaaacagc ctaaagtatttagatctgagcttcaatgatgttattaccatgagttcaaacttcttgggc ttagaacagctagaacatctggatttgcagcattccaatttgaaacaaatgagtgagttt tcagtattcctatcactcagaaacctcatttaccttgacatttctcatactcacaccaga gttgctttcaatggcatcttcaatggcttgtccaatctcgaagtcttgaaaatggctggc aattctttccaggaaaacttccttccagatatcttcacagagctgagaaacttgaccttc ctggacctctctcagtgtcgactggagcaattgtctccaacagcatttaactcactctcc agtcttcaggtactaaatatgagccacaacaacttcttttcattggatacgtttccttat aagtgtctgaactccctccaggttcttgattacagtctcaatcacataatgacttccaaa aaacaggaactacagcattttccaagtagtctagccttcttaaatcttactcagaatgac tttgcttgtacttgtgaacacgagagtttcctgcagtggatcaaggaccagaggcagctc ttggtggaagttgaacgaatggaatgtgcaacaccttcagataagcagggcatgcctgtg ctgagtttgaatatcacctgtcagatgaataagaccatcattggtgtgtcagtcctcagt gtgcttgtagtatctgtggtagcagttctggtctataagttctattttcacctgatgctt cttgctggctgcataaagtatggtagaggtgaaaacacctatgatgcctttgttatctac tcaagccaggatgaggactgggtaaggaatgagctagtaaagaatttagaagaaggggtg cctccctttcagctctgccttcactacagagactttattcccggtgtggccattgctgcc aacatcatccatgaaggtttccataaaagccgaaaggtgattgttgtggtgtcccagcac ttcatccagagccgctggtgtatctttgagtatgagattgctcagacctggcagtttctg agcagtcgtgctgggatcatcttcattgtcctgcagaaggtggagaagaccctgctcagg cagcaggtggagctgtaccgccttctcagcaggaacacttacctggagtgggaggatagt gtcctggggcggcacatcttctggagacgactcagaaaagccctgctggatggtaaatca tggaatccagaaggaacagtgggtacaggatgcaattag

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