KEGG   Symphalangus syndactylus (siamang): 129482269
Entry
129482269         CDS       T10134                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial isoform X1
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn00140  Steroid hormone biosynthesis
ssyn01100  Metabolic pathways
ssyn04913  Ovarian steroidogenesis
ssyn04925  Aldosterone synthesis and secretion
ssyn04927  Cortisol synthesis and secretion
ssyn04934  Cushing syndrome
Module
ssyn_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    129482269
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    129482269
   04925 Aldosterone synthesis and secretion
    129482269
   04927 Cortisol synthesis and secretion
    129482269
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    129482269
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:ssyn00199]
    129482269
Enzymes [BR:ssyn01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     129482269
Cytochrome P450 [BR:ssyn00199]
 Cytochrome P450, animal type
  CYP11 family
   129482269
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 129482269
NCBI-ProteinID: XP_055133778
LinkDB
Position
5:31505749..31581022
AA seq 521 aa
MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWL
NLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPER
FLIPPWVAYHQYYQRPVGVLLKKSAAWKKDRVALNQEVMAPETTKNFLPLLDAVSRDFVS
VLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQM
FHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRG
ILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSVTLQWHLYEMARNLKVQDMLRAEVLAAR
RQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIY
ALGREPTFFFDPENFDPTRWLSKDKNVTYFRNLGFGWGVRQCLGRRIAELEMTIFLINML
ENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQE
NT seq 1566 nt   +upstreamnt  +downstreamnt
atgctggccaagggtcttcccccacgctcagtcctggtcaaaggctgccagacctttctg
agtgcccccagggaggggctggggcgtctcagggtgcccactggcgagggggctggcatc
tccacgcgcagtcctcgccccttcaatgagatcccctctcctggtgacaatggctggcta
aacctgtaccatttctggagggagacaggcacacacaaagtccaccttcaccatgtccag
aatttccagaagtatggcccgatttacagggagaagctcggcaacgtggagtcggtttat
gtcatcgaccctgaagatgtggctcttctctttaagtccgagggccccaacccagaacgg
ttcctcatcccgccctgggtcgcctatcaccagtattaccagagacccgtaggagtcctg
ttgaagaagtcggcagcctggaagaaagaccgggtggccctgaaccaggaggtgatggct
ccagagaccaccaagaactttttgcccctgttggatgcagtgtctcgggacttcgtcagt
gtcctgcacaggcgcatcaagaaggcgggctctggaaattattcaggggacatcagtgat
gacctgtttcgctttgcctttgagtccatcactaacgtcatttttggggagcgccagggg
atgctggaggaagtagtgaaccccgaggcccagcgattcattgatgccatctaccagatg
tttcacaccagcgtccccatgctcaaccttcccccagacctgttccgtctgttcaggacc
aagacctggaaggaccatgtggctgcatgggacgtgattttcagtaaagctgacatatac
acccagaacttctactgggaattgagacagaaaggaagtgttcaccacgattaccgtggc
atcctctacagactcctgggagacagcaagatgtccttcgaggacatcaaggccaacgtc
acggagatgctggcaggaggggtggacacgacgtccgtgaccctgcagtggcacttgtac
gagatggcacgcaacctgaaggtgcaggatatgctgcgggcagaggtcttggctgcgcgg
cgccaggcccagggagacatggccacgatgctgcagctggtccccctcctcaaagccagc
atcaaggagacactaagacttcaccccatctccgtgaccctgcagagatatcttgtaaat
gacttggttcttcgagattacatgattcctgccaagacactggtgcaggtggccatctat
gctctgggccgagagcccaccttcttcttcgacccggaaaattttgacccaacccgatgg
ctgagcaaagacaagaatgtcacctacttccggaacttgggctttggctggggtgtgcgg
cagtgtctgggacggcggatcgctgagctagagatgaccatcttcctcatcaatatgctg
gagaacttcagagttgaaatccaacacctcagcgatgtgggcaccacattcaacctcatc
ctgatgcctgaaaagcccatctccttcaccttctggccctttaaccaggaagcaacccag
gagtga

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