Symphalangus syndactylus (siamang): 129490162
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Entry
129490162 CDS
T10134
Symbol
GNE
Name
(RefSeq) bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase isoform X1
KO
K12409
bifunctional UDP-N-acetylglucosamine 2-epimerase / N-acetylmannosamine kinase [EC:
3.2.1.183
2.7.1.60
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00520
Amino sugar and nucleotide sugar metabolism
ssyn00541
Biosynthesis of various nucleotide sugars
ssyn01100
Metabolic pathways
ssyn01250
Biosynthesis of nucleotide sugars
Module
ssyn_M00955
CMP-Neu5Ac/Neu5Gc biosynthesis, animals, UDP-GlcNAc => CMP-Neu5Ac => CMP-Neu5Gc
Brite
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.1 Phosphotransferases with an alcohol group as acceptor
2.7.1.60 N-acylmannosamine kinase
129490162 (GNE)
3. Hydrolases
3.2 Glycosylases
3.2.1 Glycosidases, i.e. enzymes that hydrolyse O- and S-glycosyl compounds
3.2.1.183 UDP-N-acetylglucosamine 2-epimerase (hydrolysing)
129490162 (GNE)
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NCBI-GeneID:
129490162
NCBI-ProteinID:
XP_055149689
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Position
9:108534814..108600833
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AA seq
753 aa
AA seq
DB search
METYGYLQRESCFQGPHELYFKNLSKRNKQIMEKNGNNRKLRVCVATCNRADYSKLAPIM
FGIKTEPEFFELDVVVLGSHLIDDYGNTYRMIEQDDFDINTRLHTIVRGEDEAAMVESVG
LALVKLPDVLNRLKPDIMIVHGDRFDALALATSAALMNIRILHIEGGEVSGTIDDSIRHA
ITKLAHYHVCCTRSAEQHLISMCEDHDRILLAGCPSYDKLLSAKNKDYMSVIRMWLGDDV
KSKDYIVALQHPVTTDIKHSIKMFELTLDALISFNKRTLVLFPNIDAGSKEMVRVMRKKG
IEHHPNFRAVKHVPFDQFIQLVAHAGCMIGNSSCGVREVGAFGTPVINLGTRQIGRETGE
NVLHVRDADTQDKILQALHLQFGKQYPCSKIYGDGNAVPRILKFLKSIDLQEPLQKKFCF
PPVKENISQDIDHILETLSALAVDLGGTNLRVAIVSMKGEIVKKYTQFNPKTYEERINLI
LQMCVEAAAEAVKLNCRILGVGISTGGRVNPREGIVLHSTKLIQEWNSVDLRTPLSDTLH
LPVWVDNDGNCAALAERKFGQGKGLENFVTLITGTGIGGGIIHQHELIHGSSFCAAELGH
LVVSLDGPDCSCGSHGCIEAYASGMALQREAKKLHDEDLLLVEGMSVPKDEAVGALHLIQ
AAKLGNAKAQSILRTAGTALGLGVVNILHTMNPSLVILSGVLASHYIHIVKDVIRQQALS
SVQDVDVVVSDLVDPALLGAASMVLDYTTRRIY
NT seq
2262 nt
NT seq
+upstream
nt +downstream
nt
atggaaacctatggttatctgcagagggagtcgtgctttcaaggaccccatgaactttat
tttaagaacctctcaaaacgaaacaagcaaatcatggagaagaatggaaataaccgaaag
ctgcgggtttgtgttgctacttgtaaccgtgcagattattctaaacttgccccgatcatg
tttggcattaaaaccgaacctgaattctttgaacttgatgttgtggtacttggctctcac
ctgatagatgactatggaaatacatatcgaatgattgaacaagatgactttgacattaac
accaggctacacacaattgtgaggggagaagatgaggcagccatggtggagtcagtaggc
ctggccctagtgaagctgccagatgtccttaatcgcctgaagcctgatatcatgattgtt
catggagacaggtttgatgccctggctctggccacatctgctgccttgatgaacatccga
atccttcacattgaaggtggggaagtcagtgggaccattgatgactctatcagacatgcc
ataacaaaactggctcattatcatgtgtgctgcacccgcagtgcagagcagcacctgata
tccatgtgtgaggaccatgatcgcatccttttggcaggctgcccttcctatgacaaactt
ctctcagccaagaacaaagactacatgagcgtcattcgcatgtggctaggtgatgatgta
aaatctaaagattacattgttgcactacagcaccctgtgaccactgacattaagcattcc
ataaaaatgtttgaattaacattggatgcacttatctcatttaacaagcggaccctagtc
ctgtttccaaatattgatgcagggagcaaagagatggttcgagtgatgcggaagaagggc
attgagcatcatcccaactttcgtgcagttaaacacgtcccatttgaccagtttatacag
ttggttgcccatgctggctgtatgattgggaacagcagctgtggggttcgagaagttgga
gcttttggaacacctgtgatcaacctgggaacacgtcagattggaagagaaacaggggag
aatgttcttcatgtccgggatgctgacacccaagacaaaatattgcaagcactgcacctt
cagtttggtaaacagtacccttgttcaaagatatatggggatggaaatgctgttccaagg
attttgaagtttctcaaatctattgatcttcaagagccactgcaaaagaaattctgcttt
cctcctgtgaaggagaatatctctcaagatattgaccatattcttgaaactctaagtgcc
ttggccgttgatctcggcgggacgaacctccgagttgcaatagtcagcatgaagggtgaa
atagttaagaagtatactcagttcaatcctaaaacctatgaagagaggattaatttaatc
ctacagatgtgtgtggaagctgcagcagaagctgtaaaactgaactgcagaattttggga
gtaggcatttccacaggtggccgtgtaaatcctcgggaaggaattgtgctgcattcaacc
aaactgatccaagagtggaactctgtggaccttaggacccccctttctgacactttgcat
ctccctgtgtgggtagacaatgatggcaactgtgctgccctggcggaaaggaaatttggc
caaggaaagggactggaaaactttgttacacttatcacaggcacaggaatcggtggtgga
attatccatcagcatgaattgatccacggaagctccttctgtgctgcagaactgggccac
cttgttgtgtctctggatgggcctgattgttcctgtggaagccacgggtgcattgaagca
tacgcctctggaatggccttgcagagggaggcaaaaaagctccatgatgaggacctgctc
ttggtggaagggatgtcagtgccaaaagatgaggccgtgggtgcactccatctcatccaa
gctgcgaaacttggcaatgcgaaggcccagagcatcctaagaacagctggaacagctttg
ggtcttggggttgtgaacatcctccataccatgaatccctcccttgtgatcctctctgga
gtcctggccagtcactatatccacattgtcaaagacgtcatccgccagcaggccttgtcc
tccgtgcaggacgtggacgtagtggtttcggatttggttgaccccgccctgctgggtgct
gccagcatggttctggactacacaacacgcaggatctactag
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