Symphalangus syndactylus (siamang): 129491018
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Entry
129491018 CDS
T10134
Symbol
PDGFRA
Name
(RefSeq) platelet-derived growth factor receptor alpha isoform X1
KO
K04363
platelet-derived growth factor receptor alpha [EC:
2.7.10.1
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn01521
EGFR tyrosine kinase inhibitor resistance
ssyn04010
MAPK signaling pathway
ssyn04014
Ras signaling pathway
ssyn04015
Rap1 signaling pathway
ssyn04020
Calcium signaling pathway
ssyn04072
Phospholipase D signaling pathway
ssyn04144
Endocytosis
ssyn04151
PI3K-Akt signaling pathway
ssyn04510
Focal adhesion
ssyn04540
Gap junction
ssyn04630
JAK-STAT signaling pathway
ssyn04810
Regulation of actin cytoskeleton
ssyn05163
Human cytomegalovirus infection
ssyn05200
Pathways in cancer
ssyn05206
MicroRNAs in cancer
ssyn05214
Glioma
ssyn05215
Prostate cancer
ssyn05218
Melanoma
ssyn05230
Central carbon metabolism in cancer
ssyn05231
Choline metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
129491018 (PDGFRA)
04014 Ras signaling pathway
129491018 (PDGFRA)
04015 Rap1 signaling pathway
129491018 (PDGFRA)
04630 JAK-STAT signaling pathway
129491018 (PDGFRA)
04020 Calcium signaling pathway
129491018 (PDGFRA)
04072 Phospholipase D signaling pathway
129491018 (PDGFRA)
04151 PI3K-Akt signaling pathway
129491018 (PDGFRA)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
129491018 (PDGFRA)
09144 Cellular community - eukaryotes
04510 Focal adhesion
129491018 (PDGFRA)
04540 Gap junction
129491018 (PDGFRA)
09142 Cell motility
04810 Regulation of actin cytoskeleton
129491018 (PDGFRA)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
129491018 (PDGFRA)
05206 MicroRNAs in cancer
129491018 (PDGFRA)
05230 Central carbon metabolism in cancer
129491018 (PDGFRA)
05231 Choline metabolism in cancer
129491018 (PDGFRA)
09162 Cancer: specific types
05214 Glioma
129491018 (PDGFRA)
05218 Melanoma
129491018 (PDGFRA)
05215 Prostate cancer
129491018 (PDGFRA)
09172 Infectious disease: viral
05163 Human cytomegalovirus infection
129491018 (PDGFRA)
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
129491018 (PDGFRA)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ssyn01001
]
129491018 (PDGFRA)
09183 Protein families: signaling and cellular processes
04090 CD molecules [BR:
ssyn04090
]
129491018 (PDGFRA)
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
129491018 (PDGFRA)
Protein kinases [BR:
ssyn01001
]
Receptor tyrosine kinases (RTK)
PDGFR family [OT]
129491018 (PDGFRA)
CD molecules [BR:
ssyn04090
]
Proteins
129491018 (PDGFRA)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Ig_3
I-set
ig
Ig_2
VEGFR1-3_N_Ig-like
VEGFR-1-like_Ig-like
V-set
Motif
Other DBs
NCBI-GeneID:
129491018
NCBI-ProteinID:
XP_055150647
LinkDB
All DBs
Position
10:complement(84775053..84840415)
Genome browser
AA seq
1089 aa
AA seq
DB search
MGTSHPAFLVLGCLLTGLSLILCQLSLPSILPNENEKVVQLNSSFSLRCFGESEVSWQYP
MSEEENSDVEIRNEENNSGLFVTVLEVSSASAAHTGLYTCYYNHTQTEENELEGRHIYIY
VPDPDVAFVPLGMTDYLVIVEDDDSAIIPCRTTDPETPVTLRNSEGVVPASYDSRQGFNG
TFTVGPYTCEATIKGKKFQTIAFNVYALKATSELDLEMEALKTVYKSGETIVVTCAVFNN
EVVDLQWTYPGEVKGKGITMLEEIKVPSIKLVYTLTVPEATVKDSGDYECAARQATREVK
EMKKVTISVHEKGFIEIKPTFSQLEAVNLHEVKHFVVEVQAYPPPRISWLKNNLTLIENL
TEITTDVEKIQEIRYRSKLKLIRAKEEDSGHYTIVAQNEDAVKSYTFELLTQVPSSILDL
VDDHHGSTGGQTVRCTAEGTPLPDIEWMICKDIKKCNNETSWTILANNVSNIITEIHPRD
RSTVEGRVTFAKVEETIAVRCLAKNLLGAENRELKLVAPTLRSELTVAAAVLVLLVIVII
SLIVLVVIWKQKPRYEIRWRVIESISPDGHEYIYVDPMQLPYDSRWEFPRDGLVLGRVLG
SGAFGKVVEGTAYGLSRSQPVMKVAVKMLKPTARSSEKQALMSELKIMTHLGPHLNIVNL
LGACTKSGPIYIITEYCFYGDLVNYLHKNRDSFLSHHPEKPKKELDIFGLNPADESTRSY
VILSFENNGDYMDMKQADTTQYVPMLERKEVSKYSDIQRSLYDRPASYKKKSMLDSEVKN
LLSDGNSEGLTLLDLLSFTYQVARGMEFLASKNCVHRDLAARNVLLAQGKIVKICDFGLA
RDIMHDSNYVSKGSTFLPVKWMAPESIFDNLYTTLSDVWSYGILLWEIFSLGGTPYPGMM
VDSTFYNKIKSGYRMAKPDHATSEVYEIMVKCWNSEPEKRPSFYHLSEIVENLLPGQYKK
SYEKIHLDFLKSDHPAVARMRVDSDNAYIGVTCKNEEDKLKDWEGGLDEQRLSADSGYII
PLPDIDPVPEEEDLGKRNRHSSQTSEESAIETGSSSSTFIKREDETIEDIDMMDDIGIDS
SDLVEDSFL
NT seq
3270 nt
NT seq
+upstream
nt +downstream
nt
atggggacttcccatccggcgttcctggtcttaggctgtcttctcacagggctgagccta
atcctctgccagctttcattaccctctatccttccaaatgaaaatgaaaaggttgtgcag
ctgaattcatccttttctctgagatgctttggggagagtgaagtgagctggcagtacccc
atgtctgaagaagagaactccgatgtggaaatcagaaatgaagaaaacaacagtggcctt
tttgtgacggtcttggaagtgagcagtgcctcggcggcccatacagggttgtacacttgt
tattacaaccacactcagacagaagagaatgagcttgaaggcaggcacatttatatctat
gtgccagacccagatgtagcctttgtacctctaggaatgacggattatttagtcatcgtg
gaggacgatgattctgccatcataccttgtcgcacaactgatcccgagaccccggtaacc
ttacgcaacagtgagggggtggtacctgcctcctacgacagcagacagggctttaatggg
accttcactgtagggccgtatacctgtgaggccaccatcaaaggaaagaagttccagacc
atcgcatttaacgtttatgctttaaaagcaacatcagagctggatctagaaatggaagct
cttaaaactgtgtataagtcaggggaaacgattgtggtcacctgtgctgttttcaacaat
gaggtggttgaccttcaatggacgtaccctggagaagtgaaaggcaaaggcatcacaatg
ctggaagaaatcaaagtcccatccatcaaattggtgtacactttgacggtccccgaggcc
acggtgaaagacagtggagattacgaatgtgctgcccgccaggctaccagggaggtcaaa
gaaatgaagaaagtcactatttctgtccatgagaaagggttcattgaaatcaaacctacc
ttcagccagttggaagctgtcaacctgcatgaagtcaaacattttgttgtagaggtgcag
gcctacccacctcccaggatatcctggctgaaaaacaatctgactctgattgaaaatctc
actgagatcaccactgacgtggaaaagattcaggaaataaggtatcgaagcaaattaaag
ctgatccgtgctaaggaagaagacagtggccattatactattgtagctcaaaatgaagat
gctgtgaagagctatacttttgaactgttaactcaagttccttcatccattctggactta
gtcgatgatcaccatggctcaactgggggacagacagtgaggtgcacagctgaaggcacg
ccgcttcctgatattgagtggatgatatgcaaggatattaagaaatgtaataatgaaact
tcctggacgattttggccaacaatgtctcaaatatcatcacggagatccacccccgagac
aggagtaccgtggagggccgtgtgactttcgccaaagtggaggagaccattgcggtgcga
tgcctggctaagaatctccttggagccgagaaccgagagctgaagctggtggctcccacc
ctgcgttctgaactcacggtggctgctgcagtcctggtgctgctggtgattgtgatcatc
tcactcattgtcctggttgtcatttggaaacagaaaccgaggtatgaaattcgctggaga
gtcattgaatcaatcagcccggatggacatgaatatatttatgtggacccgatgcagctg
ccttatgactcaagatgggagtttccaagggatggactagtgcttggtcgggtcttgggg
tctggagcgtttgggaaggtggttgaaggaacagcctatggattaagccggtcccaacct
gtcatgaaagttgcagtgaagatgctaaaacccacggccagatccagtgaaaaacaagct
ctcatgtctgaactgaagataatgactcacctggggccacatttgaacattgtaaacttg
ctgggagcctgcaccaagtcaggtcccatttacatcatcacggagtactgcttctatgga
gatttggtcaactatttgcataagaatagggatagcttcctgagccaccacccagagaag
ccaaagaaagagctggatatctttggattgaaccctgctgatgaaagcacacggagctat
gttattttatcttttgaaaacaatggtgactacatggacatgaagcaggctgatactaca
cagtatgtccccatgctagaaaggaaagaggtttctaaatattccgacatccagagatca
ctctatgatcgtccagcctcatataagaagaaatctatgttagactcagaagtcaaaaac
ctcctttcagatggtaactcagaaggccttactttattggatttgttgagcttcacctat
caagttgcccgaggaatggagtttttggcttcaaaaaattgtgtccaccgtgatctggct
gctcgcaacgtcctcctggcacaaggaaaaatcgtgaagatctgtgactttggcctggcc
agagacatcatgcatgattcgaactacgtgtcgaaaggcagtacctttctgcccgtgaag
tggatggctcctgagagcatctttgacaacctctacaccacattgagtgatgtctggtct
tacggcattctgctctgggagatcttttcccttggtggcaccccttaccccggcatgatg
gtggattctactttctacaataagatcaagagtgggtaccggatggccaagcctgaccac
gctaccagtgaagtctacgagatcatggtgaaatgctggaacagtgagccggagaagaga
ccctccttttaccacctgagtgagattgtggagaatctgctgcctggacaatataagaag
agttatgaaaaaattcacctggacttcctgaagagtgaccatcctgctgtggcacgcatg
cgtgtggactcagacaatgcgtacattggtgtcacctgcaaaaacgaggaagacaagctg
aaggactgggagggtggtctggatgagcagagactgagcgctgacagtggctacatcatt
cctttgcctgacattgaccctgtgcctgaggaggaggacctgggcaagaggaacagacac
agttcgcagacctctgaagagagcgccattgagacgggttccagcagttccaccttcatc
aagagagaggacgagaccattgaagacatcgacatgatggatgacatcgggatagactct
tcagacctggtggaagacagcttcctgtaa
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