Symphalangus syndactylus (siamang): 129491548
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Entry
129491548 CDS
T10134
Symbol
IKBKB
Name
(RefSeq) inhibitor of nuclear factor kappa-B kinase subunit beta isoform X1
KO
K07209
inhibitor of nuclear factor kappa-B kinase subunit beta [EC:
2.7.11.10
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn01523
Antifolate resistance
ssyn04010
MAPK signaling pathway
ssyn04014
Ras signaling pathway
ssyn04062
Chemokine signaling pathway
ssyn04064
NF-kappa B signaling pathway
ssyn04068
FoxO signaling pathway
ssyn04150
mTOR signaling pathway
ssyn04151
PI3K-Akt signaling pathway
ssyn04210
Apoptosis
ssyn04380
Osteoclast differentiation
ssyn04620
Toll-like receptor signaling pathway
ssyn04621
NOD-like receptor signaling pathway
ssyn04622
RIG-I-like receptor signaling pathway
ssyn04623
Cytosolic DNA-sensing pathway
ssyn04625
C-type lectin receptor signaling pathway
ssyn04657
IL-17 signaling pathway
ssyn04658
Th1 and Th2 cell differentiation
ssyn04659
Th17 cell differentiation
ssyn04660
T cell receptor signaling pathway
ssyn04662
B cell receptor signaling pathway
ssyn04668
TNF signaling pathway
ssyn04722
Neurotrophin signaling pathway
ssyn04910
Insulin signaling pathway
ssyn04920
Adipocytokine signaling pathway
ssyn04930
Type II diabetes mellitus
ssyn04931
Insulin resistance
ssyn04932
Non-alcoholic fatty liver disease
ssyn04936
Alcoholic liver disease
ssyn05010
Alzheimer disease
ssyn05132
Salmonella infection
ssyn05135
Yersinia infection
ssyn05142
Chagas disease
ssyn05145
Toxoplasmosis
ssyn05160
Hepatitis C
ssyn05161
Hepatitis B
ssyn05162
Measles
ssyn05163
Human cytomegalovirus infection
ssyn05164
Influenza A
ssyn05165
Human papillomavirus infection
ssyn05166
Human T-cell leukemia virus 1 infection
ssyn05167
Kaposi sarcoma-associated herpesvirus infection
ssyn05168
Herpes simplex virus 1 infection
ssyn05169
Epstein-Barr virus infection
ssyn05170
Human immunodeficiency virus 1 infection
ssyn05171
Coronavirus disease - COVID-19
ssyn05200
Pathways in cancer
ssyn05206
MicroRNAs in cancer
ssyn05208
Chemical carcinogenesis - reactive oxygen species
ssyn05212
Pancreatic cancer
ssyn05215
Prostate cancer
ssyn05220
Chronic myeloid leukemia
ssyn05221
Acute myeloid leukemia
ssyn05222
Small cell lung cancer
ssyn05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
ssyn05417
Lipid and atherosclerosis
ssyn05418
Fluid shear stress and atherosclerosis
Brite
Enzymes [BR:
ssyn01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.10 IkappaB kinase
129491548 (IKBKB)
Protein kinases [BR:
ssyn01001
]
Serine/threonine kinases: Other
IKK family [OT]
129491548 (IKBKB)
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Gene cluster
GFIT
Other DBs
NCBI-GeneID:
129491548
NCBI-ProteinID:
XP_055152041
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Position
10:134883580..134944357
Genome browser
AA seq
756 aa
AA seq
DB search
MSWSPSLTTQTCGAWEMKERLGTGGFGNVIRWHNQETGEQIAIKQCRQELSPRNRERWCL
EIQIMRRLTHPNVVAARDVPEGMQNLAPNDLPLLAMEYCQGGDLRKYLNQFENCCGLREG
AILTLLSDIASALRYLHENRIIHRDLKPENIVLQQGEQRLIHKIIDLGYAKELDQGSLCT
SFVGTLQYLAPELLEQQKYTVTVDYWSFGTLAFECITGFRPFLPNWQPVQWHSKVRQKSE
VDIVVSEDLNGTVKFSSSLPYPNNLNSVLAERLEKWLQLMLMWHPRQRGTDPTYGPNGCF
KALDDILNLKLVHILNMVTGTIHTYPVTEDESLQSLKARIQQDTGIPEEDQELLQEAGLA
LIPDKPATQCISDGKLNEGRTLDMDLVFLFDNGKITYETQISPRPQPESVSCILQEPKRN
LAFFQLRKVWGQVWHSIQTLKEDCNRLQQGQRAAMMNLLRNNSCLSKMKNSMASMSQQLK
AKLDFFKTSIQIDLEKYSEQTEFGIASDKLLLAWREMEQAVELCGRENEVKLLVERMMAL
QTDIVDLQRSPMGRKQGGTLDDLEEQARELYRRLREKPRDQRTEGDSQEMVRLLLQAIQS
FEKKVRVIYTQLSKTVVCKQKALELLPKVEEVVSLMNEDEKTVVRLQEKRQKELWNLLKI
ACSKVRGPVSGSPDSMNASRLSQPGQLMSQPSTASNSLPEPAKKSEELVAEAHNLCTLLE
NAIQDTVREQDQSFTALDWSWLQAEEEEHSCLEQTS
NT seq
2271 nt
NT seq
+upstream
nt +downstream
nt
atgagctggtcaccttccctgacaacgcagacatgtggggcctgggaaatgaaagagcgc
cttgggacagggggatttggaaatgtcatccgatggcacaatcaggaaacaggtgagcag
attgccatcaagcagtgccggcaggagctcagtccccggaaccgagagcggtggtgcctg
gagatccagatcatgagaaggctgacccaccccaatgtggtggctgcccgagatgtccct
gaggggatgcagaacttggcacccaatgacctgcccctgctggccatggagtactgccaa
ggaggagatctccggaagtacctgaatcagtttgagaactgctgcggtctgcgggaaggc
gccatcctcaccttgctgagtgacattgcctctgcgcttagataccttcatgaaaacaga
atcatccatcgggatctaaagccagaaaacatcgtcctgcagcaaggagaacagaggtta
atacacaaaattattgacctaggatatgccaaggagctggatcagggcagtctttgcact
tcattcgtggggaccctgcagtacctggccccagagctactggagcagcagaagtacaca
gtgaccgtcgactactggagcttcggaaccctggcctttgagtgcatcacgggcttccgg
cccttcctccccaactggcagcccgtgcagtggcattcgaaagtgcggcagaagagtgag
gtggacattgttgttagcgaagacttgaatggaacagtgaagttttcaagctctttaccc
taccccaataatcttaacagcgtcctggctgagcgactggagaagtggctgcaactgatg
ttgatgtggcacccccgacagaggggcacggatcccacgtatgggcccaacggctgcttc
aaggccctggatgacatcttaaacttaaagctggttcatatcttgaacatggtcacgggc
accatccacacctaccctgtgacagaggatgagagtctgcagagcttgaaggccagaatc
cagcaggacacgggcatcccagaggaggaccaggagctgctgcaggaagcgggcctggcg
ttgatccccgataagcctgccactcagtgtatttcagacggcaagttaaatgagggccgc
acattggacatggatcttgtttttctctttgacaacggtaaaatcacctatgagactcag
atctccccacggccccaacctgaaagtgtcagctgtatccttcaagagcccaagaggaat
ctcgccttcttccagctgaggaaggtgtggggccaggtctggcatagcatccagaccctg
aaggaggattgcaaccggctgcagcagggacagcgagccgccatgatgaatctcctccga
aacaacagctgcctctccaagatgaagaattccatggcttccatgtctcagcagctcaag
gccaagttggatttcttcaaaaccagcatccagattgacctggagaagtacagcgagcaa
accgagtttgggatcgcatcagataaactgctgctggcctggagggaaatggagcaggct
gtggagctctgtgggcgggagaacgaagtgaaactcctggtagaacggatgatggctctg
cagaccgacatcgtggacttacagaggagccccatgggccggaagcaggggggaacgctg
gacgacctagaggagcaagcaagggagctgtacaggagactaagggaaaaacctcgagac
cagcgaactgagggtgacagtcaggaaatggtacggctgctgcttcaggcaattcagagc
ttcgagaagaaagtgcgagtgatctatacacagctcagtaaaactgtggtttgcaagcag
aaggcactagaactgttgcccaaggtggaagaggtggtgagcttaatgaatgaggatgag
aagactgttgtccggctgcaggagaagcggcagaaggagctctggaatctcctgaagatt
gcttgtagcaaggtccgtggtcctgtcagtggaagccccgatagcatgaacgcctctcga
cttagccagcctgggcagctgatgtctcagccctccacggcctccaacagcttacccgag
ccagccaagaagagtgaagaactggtggctgaagcacataacctctgcaccctgctagaa
aatgccatacaggacaccgtgagggaacaagaccagagtttcacggccctagactggagc
tggttacaggcggaagaagaagagcacagctgcctggagcagacctcatga
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