Symphalangus syndactylus (siamang): 129491695
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Entry
129491695 CDS
T10134
Symbol
PDHA2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
ssyn Symphalangus syndactylus (siamang)
Pathway
ssyn00010
Glycolysis / Gluconeogenesis
ssyn00020
Citrate cycle (TCA cycle)
ssyn00620
Pyruvate metabolism
ssyn00785
Lipoic acid metabolism
ssyn01100
Metabolic pathways
ssyn01200
Carbon metabolism
ssyn01210
2-Oxocarboxylic acid metabolism
ssyn04066
HIF-1 signaling pathway
ssyn04922
Glucagon signaling pathway
ssyn05230
Central carbon metabolism in cancer
ssyn05415
Diabetic cardiomyopathy
Module
ssyn_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
ssyn00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
129491695 (PDHA2)
00020 Citrate cycle (TCA cycle)
129491695 (PDHA2)
00620 Pyruvate metabolism
129491695 (PDHA2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
129491695 (PDHA2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
129491695 (PDHA2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
129491695 (PDHA2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
129491695 (PDHA2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
129491695 (PDHA2)
Enzymes [BR:
ssyn01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
129491695 (PDHA2)
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
129491695
NCBI-ProteinID:
XP_055152166
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All DBs
Position
10:complement(42383546..42384967)
Genome browser
AA seq
391 aa
AA seq
DB search
MRNMLAAFISRVLRRVAQKSARRVLVASRNSSNDATFEIKQCDLYLLEEGPPVTTVLTRA
EGLKYYRMMLTVRRMELKADQLYKQKFIRGFCHLCDGQEACCVGLEAGINPSDHVITSYR
AHGVCYTRGLSVRSILAELTGRRGGCAKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIAL
AGKYKGNDEICLTLYGDGAANQGQIAEAFNMAALWKLSCVFICENNLYAMGTSTERAAAS
SDYYKRGNFIPGLKVDGMDVLCVREATKFAADYCRSGKGPILMELQAYRFHGHSMSDPGV
SYRTREEIQEVRSKRDPIMILQDRIVSSKLATVEELKEIGTEVRKEIDDAAQFATTDIEP
HLEELGHHIYSSDSSFEVRGANPWIKFKSVS
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgaggaatatgctggctgccttcatctcccgcgtgttgaggcgagttgcccagaaatca
gctcgcagagtgctggtggcatcccgtaactcctcaaatgacgctacatttgaaattaag
caatgtgatctttatctgttggaagagggtccccctgtcactacagtgctcactagggcg
gaggggcttaaatactacaggatgatgctgactgttcgccgcatggaattgaaggcagat
cagctgtacaaacagaaattcattcgcggtttctgtcacttgtgtgatggtcaggaagcc
tgctgcgtgggccttgaggccggcataaacccctcggaccacgtcatcacatcatatagg
gctcatggtgtgtgctatactcgggggctttctgtccgatccattctcgcagagctgacg
ggaagaagaggaggttgtgctaaaggaaaaggaggatcgatgcatatgtataccaagaac
ttctacgggggcaatggcatcgtcggtgcacagggccccctgggtgctggcattgctctg
gccggtaaatataaaggaaacgatgagatctgtttgactttatatggggatggggctgcg
aatcaggggcagatagccgaagctttcaatatggcagctttatggaaattatcttgtgtt
ttcatctgtgagaataacctatatgcaatgggaacatctactgagagagcagcagccagc
tctgattactacaagaggggcaattttatccctgggctaaaggtcgatggaatggatgtt
ctgtgtgttcgtgaggcaacaaaatttgcagccgactactgtagatctggaaaggggccc
atactgatggagctgcaggcctaccgttttcatggacacagtatgagtgatcctggagtc
agttatcgtacacgagaagaaattcaggaagtaagaagtaagagggatcctataatgatt
ctccaagatagaattgtaagcagcaagctcgccactgtggaagaattaaaggaaattggg
actgaggtgaggaaagaaattgatgatgctgctcagtttgctaccactgatattgagcca
catttggaagaattaggccatcacatctacagcagtgattcatcttttgaagttcgtggt
gcaaatccatggatcaagtttaagtccgtcagttaa
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