KEGG   Symphalangus syndactylus (siamang): 134733840
Entry
134733840         CDS       T10134                                 
Symbol
ATP1A1
Name
(RefSeq) sodium/potassium-transporting ATPase subunit alpha-1 isoform X1
  KO
K01539  sodium/potassium-transporting ATPase subunit alpha [EC:7.2.2.13]
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn04022  cGMP-PKG signaling pathway
ssyn04024  cAMP signaling pathway
ssyn04260  Cardiac muscle contraction
ssyn04261  Adrenergic signaling in cardiomyocytes
ssyn04820  Cytoskeleton in muscle cells
ssyn04911  Insulin secretion
ssyn04918  Thyroid hormone synthesis
ssyn04919  Thyroid hormone signaling pathway
ssyn04925  Aldosterone synthesis and secretion
ssyn04960  Aldosterone-regulated sodium reabsorption
ssyn04961  Endocrine and other factor-regulated calcium reabsorption
ssyn04964  Proximal tubule bicarbonate reclamation
ssyn04970  Salivary secretion
ssyn04971  Gastric acid secretion
ssyn04972  Pancreatic secretion
ssyn04973  Carbohydrate digestion and absorption
ssyn04974  Protein digestion and absorption
ssyn04976  Bile secretion
ssyn04978  Mineral absorption
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04024 cAMP signaling pathway
    134733840 (ATP1A1)
   04022 cGMP-PKG signaling pathway
    134733840 (ATP1A1)
 09140 Cellular Processes
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    134733840 (ATP1A1)
 09150 Organismal Systems
  09152 Endocrine system
   04911 Insulin secretion
    134733840 (ATP1A1)
   04918 Thyroid hormone synthesis
    134733840 (ATP1A1)
   04919 Thyroid hormone signaling pathway
    134733840 (ATP1A1)
   04925 Aldosterone synthesis and secretion
    134733840 (ATP1A1)
  09153 Circulatory system
   04260 Cardiac muscle contraction
    134733840 (ATP1A1)
   04261 Adrenergic signaling in cardiomyocytes
    134733840 (ATP1A1)
  09154 Digestive system
   04970 Salivary secretion
    134733840 (ATP1A1)
   04971 Gastric acid secretion
    134733840 (ATP1A1)
   04972 Pancreatic secretion
    134733840 (ATP1A1)
   04976 Bile secretion
    134733840 (ATP1A1)
   04973 Carbohydrate digestion and absorption
    134733840 (ATP1A1)
   04974 Protein digestion and absorption
    134733840 (ATP1A1)
   04978 Mineral absorption
    134733840 (ATP1A1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    134733840 (ATP1A1)
   04961 Endocrine and other factor-regulated calcium reabsorption
    134733840 (ATP1A1)
   04964 Proximal tubule bicarbonate reclamation
    134733840 (ATP1A1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssyn04147]
    134733840 (ATP1A1)
Enzymes [BR:ssyn01000]
 7. Translocases
  7.2  Catalysing the translocation of inorganic cations
   7.2.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.2.2.13  Na+/K+-exchanging ATPase
     134733840 (ATP1A1)
Exosome [BR:ssyn04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   134733840 (ATP1A1)
  Exosomal proteins of other body fluids (saliva and urine)
   134733840 (ATP1A1)
  Exosomal proteins of colorectal cancer cells
   134733840 (ATP1A1)
  Exosomal proteins of bladder cancer cells
   134733840 (ATP1A1)
SSDB
Motif
Pfam: E1-E2_ATPase Cation_ATPase_C Cation_ATPase Cation_ATPase_N Hydrolase Hydrolase_3 HAD DUF1290
Other DBs
NCBI-GeneID: 134733840
NCBI-ProteinID: XP_063480734
LinkDB
Position
19:69036520..69068425
AA seq 1023 aa
MGKGVGRDKYEPAAVSEQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLS
RGLTCARAAEILARDGPNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAA
TEEEPQNDNLYLGVVLSAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSI
NAEEVVVGDLVEVKGGDRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETR
NIAFFSTNCVEGTARGIVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAV
FLGVSFFILSLILEYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKN
LEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLA
LSRIAGLCNRAVFQANQENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEI
PFNSTNKYQLSIHKNPNTSEPRHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQN
AYLELGGLGERVLGFCHLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVP
DAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDA
KACVVHGSDLKDMTSEQLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVN
DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL
TSNIPEITPFLIFIIANIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPK
TDKLVNERLISMAYGQIGMIQALGGFFTYFVILAENGFLPLHLLGLRVDWDDRWINDVED
SYGQQWTYEQRKIVEFTCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFE
ETALAAFLSYCPGMGVALRMYPLKPTWWFCAFPYSLLIFLYDEVRKLIIRRRPGGWVEKE
TYY
NT seq 3072 nt   +upstreamnt  +downstreamnt
atggggaagggggttggacgtgataagtatgagcccgcagctgtttcagaacaaggtgat
aaaaagggcaaaaagggcaaaaaagacagggacatggatgaactgaagaaagaagtttct
atggatgatcataaacttagccttgatgaacttcatcgtaaatatggaacagacttgagc
cggggattaacatgtgctcgtgcagctgagatccttgcgcgagatggtcccaacgccctc
actccccctcccactactcctgaatggatcaagttttgtcggcagctctttgggggattc
tcaatgttactgtggattggagcgattctttgtttcttggcttatagcatccaagctgct
acagaagaggaacctcaaaatgataatctgtacctgggtgtggtgctatcagccgttgta
atcataactggatgcttctcctactaccaagaagctaaaagttcaaagatcatggaatcc
ttcaaaaacatggtccctcagcaagcccttgtgattcgaaatggtgagaaaatgagcata
aatgcagaggaggttgtggttggggatctggtagaagtaaaaggaggggaccgaattcct
gctgacctcagaatcatatctgcaaatggctgcaaggtggataactcctcactcactggt
gaatcagaaccccagactaggtctccagatttcacaaatgaaaaccccctggagacgagg
aacattgccttcttttcaaccaattgtgttgaaggcaccgcacgtggtattgttgtctac
actggggatcgcactgtgatgggaagaattgccacacttgcttctgggctcgaaggaggc
cagacccccattgctgcagaaattgaacattttatccacatcatcacgggtgtggctgtg
ttcctgggtgtgtctttcttcatcctttctctcatccttgagtacacctggcttgaggct
gtcatcttcctcatcggtatcatcgtagccaatgtgccagaaggtttgctggccactgtc
acggtctgtctgacacttactgccaaacgcatggcgaggaaaaactgcttagtgaagaac
ttagaagctgtggagaccttggggtccacatccaccatctgctcagataaaactggaact
ctgactcagaaccggatgacagtggcccacatgtggtttgacaatcaaatccatgaagct
gatacaacagagaatcagagtggtgtctcttttgacaagacttcagctacctggcttgct
ctgtccagaattgcaggtctttgtaacagggcagtgtttcaggctaaccaggaaaaccta
cctattcttaagcgggcagttgcaggagatgcctctgagtcagcactcttaaagtgcata
gagctgtgctgtggttccgtgaaggagatgagagaaagatacgccaaaatcgtcgagata
cccttcaactccaccaacaagtaccagttgtccattcataagaaccccaacacgtcggag
ccccgacacctgttggtgatgaagggcgccccggaaaggatcctagaccgttgcagctct
atcctcctccacggcaaggagcagcccctggatgaggagctgaaagacgcctttcagaat
gcctatttggagctggggggcctcggagaacgagtcctaggtttctgccacctctttctg
ccagatgaacagtttcctgaagggttccagtttgacactgacgatgtgaatttccctatc
gataatctgtgctttgttgggctcatctccatgattgaccctccacgggcggccgttcct
gatgccgtgggcaaatgtcgaagtgctggaattaaggtcatcatggtcacaggagaccat
ccaatcacagctaaagctattgccaaaggtgtgggcatcatctcagaaggcaatgagacc
gtagaagacattgctgcccgcctcaacatcccagtcagccaggtgaaccccagggatgcc
aaggcctgcgtagtacatggcagtgatctaaaggacatgacctccgagcagctggatgac
attttgaagtaccacactgagattgtgtttgccaggacctcccctcagcagaagctcatc
attgtggaaggctgccagagacagggtgctatcgtggctgtgactggtgatggtgtgaat
gactctccagctttgaagaaagcagacattggggttgctatggggattgctggctcagat
gtgtccaagcaagctgctgacatgattcttttggatgacaactttgcctcaattgtgact
ggagtagaggaaggtcgtctgatctttgataacttgaagaaatccattgcttatacctta
accagtaacattcccgagatcaccccattcctgatatttattattgcaaacattccgcta
ccactggggactgtcaccatcctctgcattgacttgggcactgacatggttcctgccatc
tccctggcttatgagcaggctgagagtgacatcatgaagagacagcccagaaatcccaaa
acagacaaacttgtgaatgagcggctgatcagcatggcctatgggcagattggtatgatc
caggccctgggcggtttctttacttattttgtgattctggctgagaacggcttcctcccg
cttcacctgttgggcctccgagtggactgggatgaccgctggatcaacgatgtggaagac
agctacgggcagcagtggacctatgagcagaggaaaatcgtggagttcacctgccacaca
gccttcttcgtcagtatcgtggtggtgcagtgggccgacttggtcatctgtaagaccagg
aggaattcggtcttccagcaggggatgaagaacaagatcttgatatttggcctctttgaa
gagacggccctggctgctttcctttcctactgccctggaatgggtgttgctcttaggatg
tatcccctcaaacctacctggtggttctgtgccttcccctactctcttctcatcttccta
tatgacgaagtcagaaaactcatcatcaggcgacgccctggaggctgggtggagaaggaa
acctactactag

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