KEGG   Symphalangus syndactylus (siamang): 134734188
Entry
134734188         CDS       T10134                                 
Symbol
NRAS
Name
(RefSeq) GTPase NRas
  KO
K07828  GTPase NRas
Organism
ssyn  Symphalangus syndactylus (siamang)
Pathway
ssyn01521  EGFR tyrosine kinase inhibitor resistance
ssyn01522  Endocrine resistance
ssyn04010  MAPK signaling pathway
ssyn04012  ErbB signaling pathway
ssyn04014  Ras signaling pathway
ssyn04015  Rap1 signaling pathway
ssyn04062  Chemokine signaling pathway
ssyn04068  FoxO signaling pathway
ssyn04071  Sphingolipid signaling pathway
ssyn04072  Phospholipase D signaling pathway
ssyn04137  Mitophagy - animal
ssyn04140  Autophagy - animal
ssyn04150  mTOR signaling pathway
ssyn04151  PI3K-Akt signaling pathway
ssyn04210  Apoptosis
ssyn04211  Longevity regulating pathway
ssyn04213  Longevity regulating pathway - multiple species
ssyn04218  Cellular senescence
ssyn04360  Axon guidance
ssyn04370  VEGF signaling pathway
ssyn04371  Apelin signaling pathway
ssyn04540  Gap junction
ssyn04550  Signaling pathways regulating pluripotency of stem cells
ssyn04625  C-type lectin receptor signaling pathway
ssyn04650  Natural killer cell mediated cytotoxicity
ssyn04660  T cell receptor signaling pathway
ssyn04662  B cell receptor signaling pathway
ssyn04664  Fc epsilon RI signaling pathway
ssyn04714  Thermogenesis
ssyn04720  Long-term potentiation
ssyn04722  Neurotrophin signaling pathway
ssyn04725  Cholinergic synapse
ssyn04726  Serotonergic synapse
ssyn04730  Long-term depression
ssyn04810  Regulation of actin cytoskeleton
ssyn04910  Insulin signaling pathway
ssyn04912  GnRH signaling pathway
ssyn04915  Estrogen signaling pathway
ssyn04916  Melanogenesis
ssyn04917  Prolactin signaling pathway
ssyn04919  Thyroid hormone signaling pathway
ssyn04921  Oxytocin signaling pathway
ssyn04926  Relaxin signaling pathway
ssyn04929  GnRH secretion
ssyn04933  AGE-RAGE signaling pathway in diabetic complications
ssyn04935  Growth hormone synthesis, secretion and action
ssyn05010  Alzheimer disease
ssyn05022  Pathways of neurodegeneration - multiple diseases
ssyn05034  Alcoholism
ssyn05160  Hepatitis C
ssyn05161  Hepatitis B
ssyn05163  Human cytomegalovirus infection
ssyn05165  Human papillomavirus infection
ssyn05166  Human T-cell leukemia virus 1 infection
ssyn05167  Kaposi sarcoma-associated herpesvirus infection
ssyn05170  Human immunodeficiency virus 1 infection
ssyn05200  Pathways in cancer
ssyn05203  Viral carcinogenesis
ssyn05205  Proteoglycans in cancer
ssyn05206  MicroRNAs in cancer
ssyn05207  Chemical carcinogenesis - receptor activation
ssyn05208  Chemical carcinogenesis - reactive oxygen species
ssyn05210  Colorectal cancer
ssyn05211  Renal cell carcinoma
ssyn05213  Endometrial cancer
ssyn05214  Glioma
ssyn05215  Prostate cancer
ssyn05216  Thyroid cancer
ssyn05218  Melanoma
ssyn05219  Bladder cancer
ssyn05220  Chronic myeloid leukemia
ssyn05221  Acute myeloid leukemia
ssyn05223  Non-small cell lung cancer
ssyn05224  Breast cancer
ssyn05225  Hepatocellular carcinoma
ssyn05226  Gastric cancer
ssyn05230  Central carbon metabolism in cancer
ssyn05231  Choline metabolism in cancer
ssyn05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ssyn05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ssyn00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    134734188 (NRAS)
   04012 ErbB signaling pathway
    134734188 (NRAS)
   04014 Ras signaling pathway
    134734188 (NRAS)
   04015 Rap1 signaling pathway
    134734188 (NRAS)
   04370 VEGF signaling pathway
    134734188 (NRAS)
   04371 Apelin signaling pathway
    134734188 (NRAS)
   04068 FoxO signaling pathway
    134734188 (NRAS)
   04072 Phospholipase D signaling pathway
    134734188 (NRAS)
   04071 Sphingolipid signaling pathway
    134734188 (NRAS)
   04151 PI3K-Akt signaling pathway
    134734188 (NRAS)
   04150 mTOR signaling pathway
    134734188 (NRAS)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    134734188 (NRAS)
   04137 Mitophagy - animal
    134734188 (NRAS)
  09143 Cell growth and death
   04210 Apoptosis
    134734188 (NRAS)
   04218 Cellular senescence
    134734188 (NRAS)
  09144 Cellular community - eukaryotes
   04540 Gap junction
    134734188 (NRAS)
   04550 Signaling pathways regulating pluripotency of stem cells
    134734188 (NRAS)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    134734188 (NRAS)
 09150 Organismal Systems
  09151 Immune system
   04625 C-type lectin receptor signaling pathway
    134734188 (NRAS)
   04650 Natural killer cell mediated cytotoxicity
    134734188 (NRAS)
   04660 T cell receptor signaling pathway
    134734188 (NRAS)
   04662 B cell receptor signaling pathway
    134734188 (NRAS)
   04664 Fc epsilon RI signaling pathway
    134734188 (NRAS)
   04062 Chemokine signaling pathway
    134734188 (NRAS)
  09152 Endocrine system
   04910 Insulin signaling pathway
    134734188 (NRAS)
   04929 GnRH secretion
    134734188 (NRAS)
   04912 GnRH signaling pathway
    134734188 (NRAS)
   04915 Estrogen signaling pathway
    134734188 (NRAS)
   04917 Prolactin signaling pathway
    134734188 (NRAS)
   04921 Oxytocin signaling pathway
    134734188 (NRAS)
   04926 Relaxin signaling pathway
    134734188 (NRAS)
   04935 Growth hormone synthesis, secretion and action
    134734188 (NRAS)
   04919 Thyroid hormone signaling pathway
    134734188 (NRAS)
   04916 Melanogenesis
    134734188 (NRAS)
  09156 Nervous system
   04725 Cholinergic synapse
    134734188 (NRAS)
   04726 Serotonergic synapse
    134734188 (NRAS)
   04720 Long-term potentiation
    134734188 (NRAS)
   04730 Long-term depression
    134734188 (NRAS)
   04722 Neurotrophin signaling pathway
    134734188 (NRAS)
  09158 Development and regeneration
   04360 Axon guidance
    134734188 (NRAS)
  09149 Aging
   04211 Longevity regulating pathway
    134734188 (NRAS)
   04213 Longevity regulating pathway - multiple species
    134734188 (NRAS)
  09159 Environmental adaptation
   04714 Thermogenesis
    134734188 (NRAS)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    134734188 (NRAS)
   05206 MicroRNAs in cancer
    134734188 (NRAS)
   05205 Proteoglycans in cancer
    134734188 (NRAS)
   05207 Chemical carcinogenesis - receptor activation
    134734188 (NRAS)
   05208 Chemical carcinogenesis - reactive oxygen species
    134734188 (NRAS)
   05203 Viral carcinogenesis
    134734188 (NRAS)
   05230 Central carbon metabolism in cancer
    134734188 (NRAS)
   05231 Choline metabolism in cancer
    134734188 (NRAS)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    134734188 (NRAS)
  09162 Cancer: specific types
   05210 Colorectal cancer
    134734188 (NRAS)
   05225 Hepatocellular carcinoma
    134734188 (NRAS)
   05226 Gastric cancer
    134734188 (NRAS)
   05214 Glioma
    134734188 (NRAS)
   05216 Thyroid cancer
    134734188 (NRAS)
   05221 Acute myeloid leukemia
    134734188 (NRAS)
   05220 Chronic myeloid leukemia
    134734188 (NRAS)
   05218 Melanoma
    134734188 (NRAS)
   05211 Renal cell carcinoma
    134734188 (NRAS)
   05219 Bladder cancer
    134734188 (NRAS)
   05215 Prostate cancer
    134734188 (NRAS)
   05213 Endometrial cancer
    134734188 (NRAS)
   05224 Breast cancer
    134734188 (NRAS)
   05223 Non-small cell lung cancer
    134734188 (NRAS)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    134734188 (NRAS)
   05170 Human immunodeficiency virus 1 infection
    134734188 (NRAS)
   05161 Hepatitis B
    134734188 (NRAS)
   05160 Hepatitis C
    134734188 (NRAS)
   05163 Human cytomegalovirus infection
    134734188 (NRAS)
   05167 Kaposi sarcoma-associated herpesvirus infection
    134734188 (NRAS)
   05165 Human papillomavirus infection
    134734188 (NRAS)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    134734188 (NRAS)
   05022 Pathways of neurodegeneration - multiple diseases
    134734188 (NRAS)
  09165 Substance dependence
   05034 Alcoholism
    134734188 (NRAS)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    134734188 (NRAS)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    134734188 (NRAS)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    134734188 (NRAS)
   01522 Endocrine resistance
    134734188 (NRAS)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ssyn04131]
    134734188 (NRAS)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ssyn04147]
    134734188 (NRAS)
   04031 GTP-binding proteins [BR:ssyn04031]
    134734188 (NRAS)
Membrane trafficking [BR:ssyn04131]
 Exocytosis
  Small GTPases and associated proteins
   Other small GTPases and associated proteins
    134734188 (NRAS)
 Endocytosis
  Macropinocytosis
   Ras GTPases
    134734188 (NRAS)
Exosome [BR:ssyn04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   134734188 (NRAS)
  Exosomal proteins of other body fluids (saliva and urine)
   134734188 (NRAS)
  Exosomal proteins of breast cancer cells
   134734188 (NRAS)
  Exosomal proteins of colorectal cancer cells
   134734188 (NRAS)
GTP-binding proteins [BR:ssyn04031]
 Small (monomeric) G-proteins
  Ras Family
   Ras [OT]
    134734188 (NRAS)
SSDB
Motif
Pfam: Ras Roc Arf GTP_EFTU MMR_HSR1 RsgA_GTPase FeoB_N Septin Ldh_1_N
Other DBs
NCBI-GeneID: 134734188
NCBI-ProteinID: XP_063481916
LinkDB
Position
19:complement(67359838..67368354)
AA seq 189 aa
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGETCLLDILDTAG
QEEYSAMRDQYMRTGEGFLCVFAINNSKSFADINLYREQIKRVKDSDDVPMVLVGNKCDL
PTRTVDTKQAHELAKSYGIPFIETSAKTRQGVEDAFYTLVREIRQYRMKKLNSSDDGTQG
CMGLPCVVM
NT seq 570 nt   +upstreamnt  +downstreamnt
atgactgagtacaaactggtggtggttggagcaggtggtgttgggaaaagcgcactgaca
atccagctaatccagaaccactttgtagatgaatatgatcccaccatagaggattcttac
agaaaacaggtggttatagatggtgaaacctgtttgttggacatactggatacagctgga
caagaagagtacagtgccatgagagaccaatacatgaggacaggcgaaggcttcctctgt
gtatttgccatcaataatagcaagtcatttgcggatattaacctctacagggagcagatt
aagcgagtaaaagactcggatgatgtacctatggtgctagtgggaaacaagtgtgatttg
ccaacaaggacagttgatacaaaacaagcccacgaactggccaagagttacgggattcca
ttcattgaaacctcagccaagaccagacagggtgttgaagatgctttttacacactggta
agagaaatacgccagtaccgaatgaaaaaactcaacagcagtgatgatgggactcagggt
tgtatgggattgccatgtgtggtgatgtaa

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