Spirochaeta thermophila DSM 6192: STHERM_c03390
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Entry
STHERM_c03390 CDS
T01315
Name
(GenBank) folylpolyglutamate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
sta
Spirochaeta thermophila DSM 6192
Pathway
sta00790
Folate biosynthesis
sta01100
Metabolic pathways
sta01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sta00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
STHERM_c03390
Enzymes [BR:
sta01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
STHERM_c03390
6.3.2.17 tetrahydrofolate synthase
STHERM_c03390
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
ADN01312
UniProt:
E0RPB8
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All DBs
Position
complement(415935..417374)
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AA seq
479 aa
AA seq
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MQLRLRTELLPAPIHPEVEEAFRYLERFANFERRPGEVRAFRLERVRTLCGLFGHPEEGL
AFAHVAGSKGKGSTCLFLARVLEESGFRTGLYTSPHLVSYTERISRAGRPWPPEVYLDAL
AFLRGRLEGTAEGRALLDEVTTFELLTVLGFLVFREMGCEWVVLETGMGGRLDATNVVRP
RVTVITHLELEHTEHLGETLEKIAFEKAGIIKPGVPVVVAPQEAGAWGVIEGRAREVGAG
VVRVERGLGASAGGVGGEVRGAQAGGGAGGSPSEVVRWEGVVRREGVGVCVEWEDGLVAR
SVLSTPLLVQAENAALAAAAWRVCVPEGKVGALEQGLAGAVLPGRLQPVAEGPELWVDGS
HTRDSVRAVVEALGRRYGWGEVVGVFGCVAGKDARGMLGELGRLCREVVVTRAGRFRESR
PEEVGRVAEGVVRAVVVPEEEAALGEALRRAEGRRPILVTGSFYLAGEILTILSRWAAS
NT seq
1440 nt
NT seq
+upstream
nt +downstream
nt
atgcagctgcgattacgtacagagctactcccggctcctattcaccccgaggttgaggag
gccttccgctacctggagcggttcgccaacttcgagcggcggccgggggaggtgcgggcg
ttccgcctggagcgggtgcggacgctctgcgggctcttcgggcacccggaggaggggctg
gcctttgcccacgtggcggggtcgaagggcaaggggtccacgtgtctcttcctcgcgcgg
gtcctggaggagtcggggttccgtaccgggctctacacctcgccgcacctggtctcctac
accgaacggataagccgggcggggaggccgtggcctcccgaggtgtacctggatgccctc
gccttcctcagggggaggctcgaggggacggccgaggggagggcgctcctcgatgaggtg
acgacgttcgagctgctgacggtgctggggttcctcgtcttcagggagatggggtgcgag
tgggtggtgctggagacggggatggggggacggctcgatgccacgaacgtggtgcggccg
cgggtgacggtgatcacgcacctggagctggagcacaccgagcacctgggggagacgctc
gagaagatcgccttcgagaaggcggggatcatcaagccgggggtgccggtggtggtggcg
ccgcaggaggcgggggcgtggggggtgatcgaggggcgggcgcgggaggtcggggcaggg
gtggtgcgggtggagagggggctgggggcgtcggcgggtggtgtgggaggggaggttcgg
ggggcgcaggccggagggggggcgggaggaagccccagcgaggtggtccggtgggagggg
gtggtgaggagggagggggtgggggtctgcgtggagtgggaggacgggctcgtggcgcgg
tcggtgctctccacaccgctcctcgtgcaggcggagaacgcagcgctcgcagcggcggcg
tggcgggtgtgtgtgccggaggggaaggtgggggcgctggagcaggggctcgccggggcg
gtcctcccggggaggctccagccggtggcagagggcccggagctgtgggtggacgggtcg
cacacgcgcgactcggtgcgggcggtggtggaggcgctggggcggaggtacgggtggggg
gaggtggtgggggtgttcgggtgcgtggcggggaaggatgcgcgggggatgctgggggaa
ctggggcggctgtgcagggaggtggtggtcacgagggcggggaggttcagggagagcagg
ccggaggaggtggggagggtggcggagggggtggtgcgggcggtggtggtgccggaggag
gaggcggccctgggggaggcgctgaggagggcggaggggcggaggcccatcctggtgaca
ggttcgttctacctggctggcgagatcctcacgatcctctcccgatgggccgcctcatga
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