Spirochaeta thermophila DSM 6192: STHERM_c16140
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Entry
STHERM_c16140 CDS
T01315
Symbol
hemD
Name
(GenBank) porphyrin biosynthesis protein HemD
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sta
Spirochaeta thermophila DSM 6192
Pathway
sta00860
Porphyrin metabolism
sta01100
Metabolic pathways
sta01110
Biosynthesis of secondary metabolites
sta01120
Microbial metabolism in diverse environments
sta01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
sta00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
STHERM_c16140 (hemD)
Enzymes [BR:
sta01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
STHERM_c16140 (hemD)
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
STHERM_c16140 (hemD)
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Porphobil_deam
TP_methylase
HEM4
DUF3322
Motif
Other DBs
NCBI-ProteinID:
ADN02554
UniProt:
E0RN85
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All DBs
Position
complement(1775405..1777423)
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AA seq
672 aa
AA seq
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MRVLRLGTRGSRLALAQVREWIARWRDASPEAGEVEWEPMVLHPRGDRDKRTPLHLVEGS
DFFTDALDEALLEGRIDVALHSAKDLPDELREGLSLAAITPLEGPREDVLVLHPRWASAS
SVDELPAGLRIGTSSARRREQLSHLRSDWELVDIRGTIEERLARVSSGEIDGVVMAKVAL
TRLALEVPHLPLPFVPHPLQGRLAAVVREGDEEVRRLCAVLDDRGRWGRVAIVGAGPGTA
DFLTLRAERLLREADLVLYDDLVYPELLAGRTAELVAVGRRKGKERYTVEEVCDLMIQAA
YAGKKVVRLKGGDPSLYARLEEELSWLRAARIPYEVVPGISAFQAASACTEIPLTSREGA
SSLLISTGYPPERALIPPPDGRLSCVYYMAGEEFPRICARFLEAGWDPHTPAVVVSAAAR
PEQTHLSLTLEDGARWTGSLPRPALLLVGATGVSRSWWEDRPHILVTGTRAAPWRARGEV
VHIPCIATVPRRDGRVQEVMEGLSSYTMLIFTSRHGVAHFVDRLLEHGDLRLLAGMRVVA
IGRVTAEALKDRGLVPDLIPEEDSAEGLVSLAAKENWRDEKILIPCSSLSDPFLQEELSR
QGNTVDAVPFYDTVPAPYPEALPLEVGAFDEVVFLSPSGVRVFRERFGALPPGIRIHTPG
ATTRRAVDDATS
NT seq
2019 nt
NT seq
+upstream
nt +downstream
nt
atgcgcgtcttgaggcttggtaccagaggaagcaggctcgccctcgcccaggtgagggag
tggatcgcgcggtggagagacgcctcgcctgaggcgggggaggtggagtgggagcctatg
gtcctccatcccagaggtgatcgcgacaagcgcacccccctccacctcgtagagggctcg
gacttcttcaccgatgccctcgatgaggccctcctggaggggaggatcgacgtggccctc
cacagcgcgaaggacctccccgacgagctccgggaggggctctcccttgcggcgatcacc
cccctcgaggggccgcgcgaggacgtcctcgtgctccacccccgatgggcgtccgcctcc
tctgtggacgagcttccggccggattgcgtatcggcaccagcagtgcgaggaggagggag
cagctctcccacctccggagcgactgggagctcgtggacatacggggcaccatagaggag
cgcctcgcacgcgtctcttccggcgagatagacggggtggtgatggccaaagtggccctc
acccgactggcactggaggtgcctcacctccccctcccctttgtcccccaccccctgcag
ggcagacttgcggcagtggtgcgggagggggacgaggaggtgcgccgcctctgcgcggtc
ctcgacgatcggggccgatggggtagggtggcgatcgtgggtgcagggcccggcactgca
gacttcctcacgctgagggccgaaagactccttcgggaggcggatctcgtcctctacgac
gacctcgtctaccccgagcttctcgcagggaggacggccgagctcgtggcggtggggagg
cggaagggaaaggagcggtacaccgtggaggaggtgtgtgacctgatgatccaggccgcc
tatgcgggaaagaaggtggtccgcctcaagggcggggatccctccctctatgcgaggctc
gaggaagagctctcctggctgagggcggcgaggataccctacgaagtggtgccggggata
agcgcctttcaggccgcctccgcctgcacagagatcccactcacgagcagggagggtgcc
tcctccctcctcatctccacagggtatcctccggagcgggccctcatccccccgccggat
gggcggctttcctgtgtgtactacatggcgggtgaggagttcccccggatatgcgcccgc
ttcctggaggcggggtgggatcctcacacccctgcggtggtggtgagtgcggcggcccgg
cccgaacagacccacctctccctcaccctggaggacggcgcgcggtggaccggatccctc
ccgcgtcccgcgctcctcctggtgggggcgaccggcgtctcccggtcgtggtgggaggac
cgtccccacatcctcgtgaccgggacgcgcgctgccccctggcgggcgcggggggaggtg
gtgcacatcccgtgcatcgccacggtcccccgacgcgatgggagggtccaggaggtgatg
gaaggcctctcctcatacaccatgctcatcttcacctcccgccatggggtggcccacttc
gtggaccgcctcctggagcacggtgatctccgcctccttgcgggcatgcgcgtggtggcc
ataggcagggtcactgccgaggcccttaaggaccgggggctcgttccagacctcatcccg
gaggaggactcggcagaggggctcgtctcgctcgcagcgaaggagaactggagggatgag
aagatcctcatcccctgttcctcgctctcggatccctttttgcaggaggagctttcccgg
caagggaataccgtggatgcggtccccttctacgataccgtccccgccccctatccagag
gcccttccgctggaggtgggcgccttcgacgaggtggtcttcctctcgccctccggcgtg
agggtcttcagggagcgcttcggcgcccttccaccggggatccgcatccataccccagga
gccaccacaaggagggcagtggacgatgctacctcttag
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