Spirochaeta thermophila DSM 6192: STHERM_c20900
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Entry
STHERM_c20900 CDS
T01315
Name
(GenBank) 3-isopropylmalate dehydratase, large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
sta
Spirochaeta thermophila DSM 6192
Pathway
sta00290
Valine, leucine and isoleucine biosynthesis
sta00660
C5-Branched dibasic acid metabolism
sta01100
Metabolic pathways
sta01110
Biosynthesis of secondary metabolites
sta01210
2-Oxocarboxylic acid metabolism
sta01230
Biosynthesis of amino acids
Module
sta_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
sta00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
STHERM_c20900
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
STHERM_c20900
Enzymes [BR:
sta01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
STHERM_c20900
4.2.1.35 (R)-2-methylmalate dehydratase
STHERM_c20900
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
ADN03021
UniProt:
E0RQW5
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Position
complement(2309601..2310887)
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AA seq
428 aa
AA seq
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MGKTVAEKIFDAHLVEEPYEGVHVLSLDRVFCHEITTPIAINDLVARGKDRVFDPARIKA
VIDHVTPAKDSKTAIQGKILREWSRRHGIEFFDIGRNGVCHALFPERGFVRPGFTVIMGD
SHTCTHGAFGAFAAGVGTTDLEVGILKGVCAFKRPRTIKVEITGRLKPGVFAKDVILSII
HRLGVNGATDRIIEFAGPVVEDFSMESRMTLCNMAVEAGATSGICYPDMVTVEYLWPFIE
DEYPNKEAALEDFGRWRPDEDAEYEEVIVHDVSDLEPLVTYGYKPDLVKPVREMEGTRVD
QVYIGSCTNGRIEDLRIAAQILKGKKIADHVRGIVSPASPGAYAQAFKEGLLEIFMEAGF
CVTNPTCGACLGMSNGVLAPGEVCASTTNRNFNGRMGKGGMVHLMSPATAAATAIAGYIT
NSPLFREG
NT seq
1287 nt
NT seq
+upstream
nt +downstream
nt
atgggaaagaccgttgcagagaagatcttcgacgcccatctggtggaggagccctatgag
ggcgttcatgtcctctccctcgacagggtcttctgccacgagatcaccacacccatcgcg
atcaacgacctcgtggcgcggggcaaggaccgggtattcgaccccgccaggatcaaggca
gtgatcgaccacgtcaccccggcgaaggactcgaagaccgcgatccagggaaagatcctg
cgggaatggtcccggaggcatgggatcgagttcttcgacatagggagaaacggggtgtgc
cacgccctcttcccggagcggggattcgtccgtcccggattcacggtgatcatgggcgac
tcccacacctgtacgcacggcgccttcggggcctttgccgcgggtgtgggtaccaccgac
ctcgaggtggggatcctcaaaggggtatgcgccttcaagagaccgcgcaccataaaggtc
gagatcaccgggaggcttaaacccggtgtcttcgcgaaggatgtgatcctctccatcatc
cacaggctcggggtgaacggggccactgatcgcatcatcgagttcgcaggtccggtggtg
gaggacttctccatggagagccggatgacgctctgcaacatggccgtggaggcaggggcc
acttccgggatctgctatcccgacatggtgacggtggagtacctctggccgttcatcgag
gacgagtatccgaacaaggaggccgccctcgaggacttcgggcggtggcggccggacgag
gatgccgagtacgaggaggtgatcgtgcacgatgtctccgatctcgaacccctcgtcacg
tacgggtacaagcccgacctcgtgaagccggtgcgcgagatggaaggcaccagggtggat
caggtctacatcggaagctgcaccaacggccggatagaggacctccgtatcgcagcccag
atcctcaaagggaagaagatcgccgaccatgtgcgtggcatcgtctctcctgcgagcccg
ggggcctatgcccaggcgttcaaggaaggtctcctcgagatattcatggaggcgggcttc
tgtgtgacgaatcccacgtgcggggcctgtctggggatgagcaacggggtgctcgcaccg
ggagaggtgtgcgcctccaccaccaaccggaacttcaacgggaggatggggaaggggggg
atggtccacctcatgagtcccgccaccgctgcggccacggcgatcgcagggtacatcacc
aattcaccgctcttcagggagggatga
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