Streptomyces tanashiensis: LDH80_12465
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Entry
LDH80_12465 CDS
T08718
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
staa
Streptomyces tanashiensis
Pathway
staa00290
Valine, leucine and isoleucine biosynthesis
staa00660
C5-Branched dibasic acid metabolism
staa01100
Metabolic pathways
staa01110
Biosynthesis of secondary metabolites
staa01210
2-Oxocarboxylic acid metabolism
staa01230
Biosynthesis of amino acids
Module
staa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
staa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
LDH80_12465 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
LDH80_12465 (leuC)
Enzymes [BR:
staa01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
LDH80_12465 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
LDH80_12465 (leuC)
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GFIT
Motif
Pfam:
Aconitase
DUF4946
AcnX
Motif
Other DBs
NCBI-ProteinID:
UZX21484
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Position
complement(2830687..2832111)
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AA seq
474 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRQNGRQVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRAQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GTTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPLARPKTMAITVDGELPEDVTA
KDLILAIIAKIGTGGGQGYILEYRGSAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLKGRAHAPEGEDWDAAVAYWKTLKSDEDAVFDAEVVIDAASLAPFVTWGTNPGQGAPL
SANVPDPASYEDASERLAAEKALEYMGLTAGQPLRDIRVDTVFVGSCTNGRIEDLRNAAS
LLEGRKVADGVRMLVVPGSVRVALQAVEEGLDKVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLSDVATTAGV
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggcctccggcagaacggccggcaggtgcggcgcctcgacctcaccatcgccacc
gaggaccacaacaccccgaccctcgacatcgacaagccgatcgccgacccggtctcccgc
gcccagctggagaccctccgcaagaactgcgccgagttcggcgtgcggctgcacccgctg
ggcgacgtcgagcagggcgtcgtccacgtcgtgggaccgcagctgggcctgacccagccc
ggcaccaccgtggtctgcggcgactcgcacacctccacgcacggcgccttcggcgcgctg
gcgttcggcatcggcaccagccaggtcgagcacgtgctcgccacccagacgctgccgctg
gcccgccccaagaccatggcgatcacggtcgacggcgagctgcccgaggacgtcaccgcc
aaggacctgatcctggcgatcatcgcgaagatcggcaccggcggcggccagggctacatc
ctggagtaccgcggctccgccatcgagaagctctcgatggaggcccggatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagaccaccttc
gcctacctgaagggccgcgcccacgcccccgagggcgaggactgggacgccgccgtcgcg
tactggaagaccctgaagtccgacgaggacgcggtcttcgacgccgaggtcgtcatcgac
gccgcctccctggcgccgttcgtcacctggggcaccaaccccggccagggtgcgccgctt
tcggcgaacgtccccgaccccgcttcgtacgaagacgcttcggagcgcctggccgccgaa
aaggccctggagtacatggggttgaccgccgggcagccgctgcgcgacatcagggtcgac
accgtcttcgtaggctcctgcaccaacggccgcatcgaggacctgcgcaacgcggcctcc
ctgctggagggccgcaaggtcgccgacggcgtccgcatgctggtcgtccccggctcggtc
cgggtcgccctgcaggccgtggaagagggcctggacaaggtcttcaaggaggccggcgcc
gaatggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccaactggccccc
ggtgagcgctccgcgtccacctccaaccgcaacttcgagggccggcagggcaagggcggc
cggacgcacctggtctccccccaggtcgccgccgccaccgccgtcctgggccacctggcc
tccccggccgatctgtccgacgtcgccaccaccgcgggggtctga
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