Streptomyces tanashiensis: LDH80_26225
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Entry
LDH80_26225 CDS
T08718
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
staa
Streptomyces tanashiensis
Pathway
staa00790
Folate biosynthesis
staa01100
Metabolic pathways
staa01240
Biosynthesis of cofactors
Module
staa_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
staa00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
LDH80_26225
Enzymes [BR:
staa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
LDH80_26225
6.3.2.17 tetrahydrofolate synthase
LDH80_26225
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UZX23987
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Position
5778762..5780261
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AA seq
499 aa
AA seq
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MSEPSDPSDQFDDIVDAETDRDPDLAVIEAGSRTLRTQGGPPQGDPVPSRPEDPELDKAL
REVETELSTRWGETKLEPSVTRIAALMDVLGEPQRAYPSIHITGTNGKTSTARMIEALLG
AFELRTGRYTSPHVQTITERISLDGAPISAERFIETYQDVKPYVELVDAREEYRLSFFEV
LTGMAYAAFADAPVDAAVVEVGMGGTWDATNVIDASVAVVTPIDLDHTDRLGGTTAEIAA
EKSGIIKQGATVILAQQPVDAAQVLLKKAVEADATVAREGMEFGIVSREVAVGGQLLTLR
GLGGEYDNVYLPLHGAYQAHNAAVALAAVEAFFGIGAEHARTLDIDTVRRAFAQVASPGR
LEIVRSSPTVLLDAAHNPHGARATAEGISEAFGFSRLIGVVSTSGDKDARGLLEAFEPIF
AEVVITANSNPRATDVDALAAIAVEVFGEDRVVVEPRLPDAIEAAITLAEEEAEYGGAGV
LVTGSIFTVGDARLLLRRG
NT seq
1500 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagccgagcgacccgagtgaccagttcgacgacatcgtcgacgccgagacagac
cgagaccccgacctcgcggtgatcgaggccggcagccgtaccctgcgcacgcagggcggc
ccgccccagggcgaccccgtgcccagccgccccgaggaccccgagctggacaaggcgctg
cgcgaggtcgagaccgagctgtcgacccgctggggcgagaccaagctggagccctccgtc
acccggatcgcggctctgatggacgtcctcggcgagccgcagcgcgcgtacccctcgatc
cacatcaccggcaccaacggcaagacgtcgacggcccgcatgatcgaggccctgctcggc
gccttcgagctgcgcaccgggcgctacacctcgccgcacgtgcagaccatcaccgagcgg
atcagcctggacggcgccccgatctccgccgagcggttcatcgagacgtaccaggacgtc
aagccgtacgtggagctggtcgacgcccgcgaggagtaccgcctctccttcttcgaggtc
ctcaccggcatggcgtacgcggccttcgcggacgccccggtcgacgcggccgtcgtcgag
gtcggcatgggcggcacctgggacgcgacgaacgtcatcgacgcctccgtcgccgtcgtc
acccccatcgacctcgaccacaccgaccggctcggcgggacgaccgccgagatcgcggcc
gagaagtccgggatcatcaagcagggcgcgaccgtcatcctggcccagcagccggtcgac
gcggcccaggtcctgctgaagaaggccgtcgaggcggacgccaccgtcgcccgcgagggc
atggagttcggcatcgtctcccgcgaggtcgcggtcggcgggcagctcctcaccctgcgc
ggcctcggcggcgagtacgacaacgtctacctgccgctgcacggcgcctaccaggcgcac
aacgccgcggtggcgctcgcggcggtcgaggccttcttcgggatcggcgccgagcacgcc
aggaccctggacatcgacaccgtccgccgggccttcgcccaggtggcctcgccgggtcgc
ctggagatcgtccgctcctcgccgaccgtcctcctggacgccgcgcacaacccgcacggg
gcgcgggcgacggcggagggcatcagcgaggccttcggcttctcccggctcatcggtgtg
gtctccacgagcggtgacaaggacgccaggggcctcctggaggccttcgagccgatcttc
gcggaggtcgtgatcacggcgaactccaacccgcgggccacggacgtggacgcgctcgcc
gcgatcgccgtcgaggtcttcggcgaggaccgggtcgtcgtcgagccgcggctgccggac
gccatcgaggcggccatcaccctcgcggaggaagaggccgagtacggcggcgcgggtgtc
ctcgtgaccggttcgatcttcacggtcggcgacgcccggctgttgctgcggaggggctga
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