Streptomyces tanashiensis: LDH80_28815
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Entry
LDH80_28815 CDS
T08718
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
staa
Streptomyces tanashiensis
Pathway
staa00300
Lysine biosynthesis
staa00550
Peptidoglycan biosynthesis
staa01100
Metabolic pathways
staa01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
staa00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
LDH80_28815 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
LDH80_28815 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
LDH80_28815 (murF)
Enzymes [BR:
staa01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
LDH80_28815 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
UZX24459
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Position
6348848..6350272
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AA seq
474 aa
AA seq
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MIALSLAEIAEIVGGQAHDIPDPAARVTGPVVIDSREVRAGSLFAAFAGEHVDGHDYAER
AVAAGAVAVLAARPVGVPALVVDDVQSALGALARAVVERLGTDVVALTGSAGKTSTKDLI
AQVLDRHAPTVWTPGSLNNEIGLPLTALRASDETRHLVLEMGARGIGHIRYLTGLTPPRI
GLVLNVGTAHIGEFGGREQIAQAKGELVEALPSAEEGGIAVLNADDPLVRAMASRTKARV
TLFGEADEAAVRAENVHLTGNGQPSFRLHTPTGCSDVTLRLYGEHHVSNALAAAAVAHEL
GMPVEEIATALSEAGTLSRWRMEVTERPDGVTIVNDAYNANPESMRAALRALAAMGRAAQ
ARGARTWAVLGKMAELGDASLVEHDAVGRLAVRLNVSKLVAVGDREASWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVALALLDTEGEVTGR
NT seq
1425 nt
NT seq
+upstream
nt +downstream
nt
gtgatcgccctctccctcgccgagatcgccgaaatcgtcggcgggcaggcgcacgacata
ccggatccggccgcccgggtcaccgggcccgtcgtcatcgactcccgcgaggtgcgggcc
ggcagcctcttcgcggccttcgccggtgagcacgtcgacggccacgactacgcggagcgc
gccgtcgcggcgggagcggtggccgtgctcgccgcccgccccgtcggcgtccccgccctc
gtcgtggacgacgtccagagcgcgctgggggccctcgcccgtgcggtcgtggaacggctc
ggcaccgacgtcgtcgccctcaccggatcggccggcaagacctccaccaaggacctgatc
gcccaggtcctcgaccggcacgcgcccaccgtgtggacgcccggctcgctcaacaacgag
atcggcctgccgctcacggcgctccgcgcgagcgacgagacccggcacctggtcctggag
atgggcgcccgcggcatcggacacatccgctacctcaccggcctcaccccgccccgtatc
ggcctcgtcctcaacgtgggcaccgcccacatcggcgagttcggcggccgggagcagatc
gcccaggcgaagggcgagctcgtcgaggccctgccgtccgccgaggagggcggaatcgcg
gtcctcaacgccgacgacccgctcgtccgcgcgatggcgagccgcaccaaggcccgcgtg
accctgttcggcgaagcggacgaagcggccgtacgggccgagaacgtccacctcacaggg
aacggacagccttctttccgtcttcacacacccaccgggtgcagtgacgtgaccttgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgcagcggccgccgtcgcgcacgagctg
ggcatgcctgtcgaagagatcgccaccgcgctctccgaggcgggcaccctgtcgcgctgg
cgcatggaggtcaccgagcgtccggacggcgtgacgatcgtcaacgacgcctacaacgcg
aaccccgagtccatgcgagccgccctgcgcgcgctcgcggccatgggcagggccgcacag
gcccgaggggctcgtacgtgggcggtgctcggcaagatggccgagctcggtgacgcatcg
ctcgtcgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtg
gcggtcggggacagggaagcgtcctggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcgcaggcggctgtcgacctgttgcgcagtgag
ctgcgcccgggggatgtcgtccttgtgaaggcttccaggtcggtcggtctcgaaaaggtc
gcgctggcgctcctcgacaccgagggcgaggtcaccggccgatga
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