Streptomyces sp. BRB040: ABDE16_26705
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Entry
ABDE16_26705 CDS
T11010
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stbr Streptomyces sp. BRB040
Pathway
stbr00300
Lysine biosynthesis
stbr00550
Peptidoglycan biosynthesis
stbr01100
Metabolic pathways
stbr01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stbr00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ABDE16_26705 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ABDE16_26705 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ABDE16_26705 (murF)
Enzymes [BR:
stbr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ABDE16_26705 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
DUF561
Motif
Other DBs
NCBI-ProteinID:
XAR13209
UniProt:
A0AAU6XLN4
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Position
6017926..6019356
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AA seq
476 aa
AA seq
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MITLSLAEIAEVVGGRMHDIPDASAEVTGPVVRDSREAGPGSLFVAFVGERVDGHDFAAQ
VVEAGAAAVLGSRPVGVPAIVVDDVQAALGALARHVVRRLGTTLVALTGSAGKTSTKDLI
AQVLRRKAPTVFTPGSMNNEVGLPLTALTATDETKFLVLEMGARGIGHIRYLCELTPPKI
GLVLNVGSAHIGEFGGREQIARAKGELVEALPPAEEGGTAVLNADDPLVRAMASRTKAKV
ILFGESGEADVRAENVRLTDTGQPSFSLHTPSGASDVTMRLYGEHHVSNALAAAAVAHEL
GMSADEIATALSEAGSLSRWRMEVTERPDGVTVVNDAYNANPESMKAALRALVAMGGAAQ
AKGGRTWAVLGKMAELGDEALAEHDAVGRLAVRLNVSKLVAVGGREARWLQLGAYNEGSW
GEESVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLESVASALLETGAEGEVAAR
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctctcactcgccgagatcgcagaagtcgtcggcgggcggatgcacgacata
ccggacgcgtccgccgaggtcaccgggccggtcgtccgggactcccgggaagcggggccc
ggcagtctcttcgtcgccttcgtcggcgaacgggtggacggccacgacttcgccgcgcag
gtcgtcgaagcgggagccgcggccgtcctcggctcccgccccgtcggcgtgcccgcgatc
gtcgtggacgacgtccaggccgccctgggcgccctcgcccggcacgtcgtacgccgcctc
ggcaccaccctcgtggccctcaccgggtcggccggcaagaccagcaccaaggacctgatc
gcccaggtcctgcgccgcaaggcgcccacggtgttcacgcccggctccatgaacaacgag
gtcgggctgccgctcaccgcgctcaccgccaccgacgagacgaagttcctcgtcctggag
atgggcgcccgcggcatcggccacatccggtacctgtgcgagctgaccccgccgaagatc
ggcctcgtcctcaacgtcggctccgcgcacatcggcgagttcggcggccgggagcagatc
gcccgggccaagggcgagctcgtcgaggcgctgccgccggccgaggagggcggcaccgcg
gtcctcaacgcggacgacccgctcgtacgggccatggcctcccgaacgaaggcgaaggtg
atccttttcggagagtccggcgaagcggacgttcgagccgagaacgtgcgactcacggac
accggacagccttccttcagccttcacacaccctccggtgcaagcgatgtgaccatgcgc
ctgtacggtgagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccacgagttg
ggcatgtccgcagacgagatcgccaccgcgctctccgaggcgggctccctctcccgctgg
cggatggaggtcaccgagcgcccggacggcgtgacggtcgtcaacgacgcctacaacgcg
aaccccgagtccatgaaggccgcgctgcgtgcgctggtcgccatgggcggagccgcacag
gcgaaagggggccgtacgtgggcggtgctcggcaagatggccgagctcggggacgaggcg
ctcgccgagcacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtc
gcggtcgggggcagggaagcccgatggctgcaactgggcgcatataacgagggttcgtgg
ggtgaggagtcggtgcacgtgtccgacgcacaggcggcggtcgacctgttgcgcagcgag
ttgcgcccaggagacgtcgtgctcgtgaaggcgtcccgttcggtgggtctggagagcgtc
gcctcggcgctgctcgagaccggcgccgagggtgaggttgccgcccgatga
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