Streptomyces sp. CMC78: SCMC78_09390
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Entry
SCMC78_09390 CDS
T11197
Name
(GenBank) CoA-acylating methylmalonate-semialdehyde dehydrogenase
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
stcm Streptomyces sp. CMC78
Pathway
stcm00280
Valine, leucine and isoleucine degradation
stcm00410
beta-Alanine metabolism
stcm00562
Inositol phosphate metabolism
stcm00640
Propanoate metabolism
stcm01100
Metabolic pathways
stcm01120
Microbial metabolism in diverse environments
stcm01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
stcm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SCMC78_09390
00562 Inositol phosphate metabolism
SCMC78_09390
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SCMC78_09390
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
SCMC78_09390
Enzymes [BR:
stcm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
SCMC78_09390
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
SCMC78_09390
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Motif
Pfam:
Aldedh
LuxC
Motif
Other DBs
NCBI-ProteinID:
BFP51132
UniProt:
A0AB33K631
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Position
1010338..1011840
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AA seq
500 aa
AA seq
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MVRELTHFIGGKQTPGTSGAYSDVYDPNTGRVQARVPLADRSETEAAISDAAEAQHAWGE
WNPQRRARVLLRFLQLVEREKDALARLLSSEHGKTVADAHGDIARGLDVVEFAAGVPHLV
KGEFSDNAGSGIDVHSLRRPLGVVAGITPFNFPAMIPLWKAAPTLACGNAFVLKPSERDP
SVPLRLAELFLEAGLPPGVLNVVNGGKETVDTLLEDPRVKALGFVGSTPIAAHIYATAAA
HGKRAQCFGGAKNHMIVMPDADLDQAVDALIGAGYGSAGERCMAISVAVPVGEATADALV
ARLTEWIGELRIGRSDDPDADFGPLVGRDAVERVRGYVDLGVEEGAELVVDGRDFTLEGH
EDGFFAGASLFDRVTPDMRIHQEEIFGPVVSVVRAADYEEALRLPSEHPYGNGVALFTRD
GDTARDFTRRVDTGMVGVNVPIPVPVAYHTFGGWKRSGFGDLNQHGPDAIRFYTRTKTVT
SRWPASGIRDGASFTIPTMG
NT seq
1503 nt
NT seq
+upstream
nt +downstream
nt
atggtccgcgaactcacccatttcatcggcggcaagcagacgcccggcacctcgggcgcc
tacagcgatgtgtacgaccccaacaccggccgggtccaggcccgggtaccgctggccgac
cgctccgagaccgaggcggccatctccgatgcggccgaggcccagcacgcgtggggcgag
tggaacccgcagcgtcgcgcgcgggtgctgctgcgcttcctccagctcgtcgagcgggag
aaggacgcgctggcccggctgctctcctccgagcacggcaagaccgtggcggacgcacac
ggcgacatcgcgcgcggactggacgtggtggagttcgccgccggtgtcccgcacctggtg
aagggcgagttcagcgacaacgccgggtccgggatcgacgtccactcgctgcgccggccg
ctcggcgtcgtcgcgggcatcaccccgttcaacttccccgcgatgattccgctgtggaag
gcggcccccactctggcctgcgggaacgccttcgtcctgaagccctccgagcgtgacccg
tcggtgccgttgcggctggccgaactgttcctcgaggcggggctgccgcccggggtgctg
aacgtcgtcaacggcggcaaggagacggtcgacaccctcttggaggacccgcgcgtcaaa
gcgctcggcttcgtaggctcgaccccgatcgccgcgcacatctacgccaccgccgccgcc
cacggcaagcgcgcgcagtgcttcggcggcgcgaagaaccacatgatcgtgatgccggac
gctgacctggaccaggcggtggacgcgctgatcggcgccggttacggctcggcgggcgag
cggtgcatggcgatctcggtcgcggtgcccgtgggcgaggccaccgccgacgcgctggtc
gcccggctcaccgaatggatcggagagctgcggatcggccgctcggacgacccggacgcc
gacttcgggccgctggtgggccgcgacgcggtggagcgggtccgcggctatgtcgacctc
ggcgtcgaggagggcgccgaactggtcgtcgacggccgcgacttcaccctggagggccat
gaggacggcttcttcgcgggcgcctcgctcttcgaccgggtcactccggacatgcggatc
caccaggaggagatcttcggcccggtggtctccgtggtccgcgcggccgactacgaggag
gcactgcggctgccctcggagcacccgtacggcaacggcgtggcgctcttcacccgcgac
ggcgacaccgcgcgcgacttcacccgccgcgtcgacaccggcatggtcggcgtcaacgtg
ccgatcccggtgccggtcgcgtaccacacgttcggcggctggaagcggtccggcttcggc
gatctgaaccagcacggtccggacgccatccgcttctacacccgtacgaagaccgtcact
tcgcgctggcccgcctcggggatccgggacggcgcgagcttcacgattccgaccatggga
tga
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