Streptomyces sp. CMC78: SCMC78_17030
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Entry
SCMC78_17030 CDS
T11197
Name
(GenBank) D-alanine--D-alanine ligase family protein
KO
K01921
D-alanine-D-alanine ligase [EC:
6.3.2.4
]
Organism
stcm Streptomyces sp. CMC78
Pathway
stcm00470
D-Amino acid metabolism
stcm00550
Peptidoglycan biosynthesis
stcm01100
Metabolic pathways
stcm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stcm00001
]
09100 Metabolism
09106 Metabolism of other amino acids
00470 D-Amino acid metabolism
SCMC78_17030
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SCMC78_17030
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SCMC78_17030
09180 Brite Hierarchies
09181 Protein families: metabolism
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
stcm01011
]
SCMC78_17030
Enzymes [BR:
stcm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.4 D-alanine---D-alanine ligase
SCMC78_17030
Peptidoglycan biosynthesis and degradation proteins [BR:
stcm01011
]
Precursor biosynthesis
Amino acid ligase
SCMC78_17030
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Dala_Dala_lig_C
Dala_Dala_lig_N
CPSase_L_D2
ATP-grasp_4
ATP-grasp
ATP-grasp_3
Motif
Other DBs
NCBI-ProteinID:
BFP51896
UniProt:
A0AB33KD08
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All DBs
Position
complement(1878786..1879961)
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AA seq
391 aa
AA seq
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MSSENLPQSPERRESPEQQRRKPRVAVVFGGRSSEHGISVVTAGAVMKAIDRTTYDVLPI
GITTDGRWALTADEPERMAIADRKVPDVDGLAESAEGSVTLSVDPGSREVLYSEPGSVPK
ALGEVDVVFPVLHGPYGEDGTLQGLLELSGVPYVGAGVLASAVGQDKEYMKRVFRSFGLP
VGPYEVVRPREWESDPAAARKRIVDFAGEHGWPLFIKPARGGSSMGITKVDGLEGLDEAI
EEARRHDPKFLVESLLRGREIECGVLEFEDGPRASVPAEIPPVTAHDFYDFEAKYIDSAA
GLVPAPLTEEQTAEVQRLAVAAFDAVSCEGLVRADFFLTEDGTFVINEINTLPGFTPISM
YPRMWQESGVDYPELVDRLIQAALKRSTGLR
NT seq
1176 nt
NT seq
+upstream
nt +downstream
nt
atgagcagcgagaacctcccccagagccctgagcgccgcgagagccctgagcagcagcgt
cgcaagccccgtgtggcggtcgtgttcggcggccgcagctccgaacacggcatctcggtc
gtcacggccggcgccgtcatgaaggccatcgaccggaccacgtacgacgtcctgccgatc
ggcatcacgacggacggccgctgggcgctcaccgcggacgagcccgaacgcatggccatc
gccgaccgcaaggtccccgatgtggacgggctcgccgagtccgccgagggcagcgtcacg
ctctccgtcgaccccggcagccgcgaggttctctacagcgaaccgggctcggtgcccaag
gcgctgggcgaggtcgacgtcgtcttccccgtgctgcacggcccgtacggcgaggacggc
accctccaggggctgctggagctctccggagtgccctacgtcggcgcgggggtcctcgcc
tccgccgtcggccaggacaaggagtacatgaagcgggtcttccgctccttcgggctgccg
gtcggaccctacgaggtcgtccgcccccgcgagtgggagagcgacccggccgccgcccgc
aagcggatcgtggacttcgccggcgagcacggctggccgctgttcatcaagcccgcccgc
ggcggctcctcgatgggcatcaccaaggtcgacggactcgaaggcctcgacgaggcgatc
gaggaggcccgccgccacgacccgaagttcctcgtcgagtcgctgctgcgcggccgcgag
atcgagtgcggggtgctggagttcgaggacggcccgcgcgccagtgtgcccgccgagatc
ccgccggtcaccgcgcacgacttctacgacttcgaggccaagtacatcgactcggccgcc
ggtctggtgcccgccccgctcaccgaggagcagaccgccgaggtgcagcggctcgccgtc
gccgccttcgacgccgtctcctgcgagggcctggtgcgggccgacttcttcctcaccgag
gacggcaccttcgtcatcaacgagatcaacaccctgccgggcttcaccccgatctcgatg
tacccgcgcatgtggcaggagagcggcgtcgactacccggagctggtcgaccggctgatc
caggccgcgttgaagcgctccaccggactgcgctga
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