KEGG   Streptomyces sp. CMC78: SCMC78_25440
Entry
SCMC78_25440      CDS       T11197                                 
Symbol
purH
Name
(GenBank) bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase
  KO
K00602  phosphoribosylaminoimidazolecarboxamide formyltransferase / IMP cyclohydrolase [EC:2.1.2.3 3.5.4.10]
Organism
stcm  Streptomyces sp. CMC78
Pathway
stcm00230  Purine metabolism
stcm00670  One carbon pool by folate
stcm01100  Metabolic pathways
stcm01110  Biosynthesis of secondary metabolites
Module
stcm_M00048  De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:stcm00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    SCMC78_25440 (purH)
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    SCMC78_25440 (purH)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:stcm04147]
    SCMC78_25440 (purH)
Enzymes [BR:stcm01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.2  Hydroxymethyl-, formyl- and related transferases
    2.1.2.3  phosphoribosylaminoimidazolecarboxamide formyltransferase
     SCMC78_25440 (purH)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.10  IMP cyclohydrolase
     SCMC78_25440 (purH)
Exosome [BR:stcm04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   SCMC78_25440 (purH)
SSDB
Motif
Pfam: AICARFT_IMPCHas MGS
Other DBs
NCBI-ProteinID: BFP52737
UniProt: A0AB33KA96
LinkDB
Position
complement(2812186..2813739)
AA seq 517 aa
MSVNKPIRRALVSVYDKTGLEDLARGLHEAGVELVSTGSTAGRIAAAGVPVTKVEELTGF
PECLDGRVKTLHPRVHAGILADLRLDAHREQLAELGVEPFDLVVVNLYPFKETVASGASD
DECVEQIDIGGPSMVRAAAKNHPSVAVVTSPERYADVLAAAKAGGFDLTARKRLAGEAFQ
HTAAYDVAVASWFADDYAAADDSGLPEFLGDTYTRKNVLRYGENPHQPAALYTSGDGGLA
EAEQLHGKEMSYNNYTDTDAARRAAHDHAEPCVAIIKHANPCGIAIADDVATAHRNAHAC
DPLSAFGGVIAVNRPVTVELAEQVAEIFTEVIVAPAYEDGAVEVLARKKNIRVLRAPDAP
AAAFEVKPIDGGALLQVADRLQADGDDPANWTLATGEALSAAELKELAFAWKACRAVKSN
AILLAKDGASVGVGMGQVNRVDSAKLAVERAGAERAAGSYAASDAFFPFPDGLEILTAAG
IKAVVQPGGSVRDELVVEAAKKAGVTMYLTGTRHFFH
NT seq 1554 nt   +upstreamnt  +downstreamnt
atgtcggtgaataagcccatccgccgcgccctggtcagtgtctacgacaagacggggctc
gaagacctcgcccgcggtctgcacgaggcgggcgtcgagctcgtctccaccggctccacc
gccggaaggatcgccgccgccggagtgccggtcaccaaggtcgaggagctcaccggcttc
cccgagtgcctggacggccgcgtcaagacgctgcacccccgcgtccacgccggcatcctc
gccgacctccgcctggacgcccaccgcgagcagctcgccgagctgggcgtcgagcccttc
gacctggtcgtggtgaacctctacccgttcaaggagaccgtcgcctcgggcgcctccgac
gacgagtgcgtcgagcagatcgacatcggcggcccctcgatggtccgcgccgccgccaag
aaccacccgtccgtggccgtcgtcaccagccccgagcggtacgccgacgtcctcgccgcc
gccaaggccggcggcttcgacctcaccgcccgcaagcggctcgccggcgaggccttccag
cacaccgccgcctacgacgtggccgtcgcctcctggttcgccgacgactacgcggccgcc
gacgactcgggcctcccggagttcctcggcgacacctacacgcgcaagaacgtcctgcgc
tacggcgagaacccgcaccagcccgccgcgctctacacctccggcgacggcggtctcgcc
gaggccgagcagctgcacggcaaggagatgtcctacaacaactacacggacaccgacgcc
gcccgccgcgccgcccacgaccacgccgagccgtgtgtcgcgatcatcaagcacgccaac
ccgtgcggcatcgccatcgccgacgacgtcgcgaccgcgcaccgcaacgcgcacgcctgc
gacccgctctccgcgttcggcggcgtcatcgccgtcaaccgcccggtgaccgtcgaactg
gccgagcaggtcgcggagatcttcaccgaggtcatcgtcgccccggcctacgaggacggc
gccgtcgaggtgctggcccgcaagaagaacatccgcgtgctgcgcgcccccgacgccccg
gccgccgcgttcgaggtcaagccgatcgacggcggcgcgctgctccaggtcgccgaccgc
ctccaggccgacggcgacgacccggccaactggacgctggccaccggcgaggcgctctcc
gcggccgagctgaaggagctggccttcgcctggaaggcctgccgcgcggtcaagtccaac
gcgatcctgctcgccaaggacggcgcctcggtcggcgtcggcatgggccaggtcaaccgc
gtcgactccgccaagctcgccgtcgagcgggccggcgcggagcgggcggccggttcgtac
gccgcctccgacgccttcttccccttccccgacggcctggagatcctcacggccgccggt
atcaaggccgtcgtccagcccggcggatccgtccgcgacgagctggtcgtcgaggccgcg
aagaaggcgggcgtgaccatgtacctcacgggcacgcgccacttcttccactga

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