Streptomyces sp. CMC78: SCMC78_37080
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Entry
SCMC78_37080 CDS
T11197
Symbol
pdhA_1
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
stcm Streptomyces sp. CMC78
Pathway
stcm00280
Valine, leucine and isoleucine degradation
stcm00640
Propanoate metabolism
stcm00785
Lipoic acid metabolism
stcm01100
Metabolic pathways
stcm01110
Biosynthesis of secondary metabolites
stcm01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stcm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
SCMC78_37080 (pdhA_1)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
SCMC78_37080 (pdhA_1)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
SCMC78_37080 (pdhA_1)
Enzymes [BR:
stcm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
SCMC78_37080 (pdhA_1)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
Transketolase_N
Motif
Other DBs
NCBI-ProteinID:
BFP53901
UniProt:
A0AB33KF50
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Position
4094062..4095222
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AA seq
386 aa
AA seq
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MTVQELPGAAAYRPTPPPAWKPITDPAPLLPDPEPYRVLGTDAVADVDPELLLRLHAELV
RGRRYNAQATALTKQGRLAVYPSSTGQEACEIAAALVLEERDWLFPSYRDTLAAVARGLD
PVEALTLLRGDRHTGYDPREHRIAPLCTPLATQLPHAVGLAHAARLKGDDVVALAMVGDG
GTSEGDFHEALNFAAVWKAPVVFFVQNNGFAISVPLAKQTAAPSLAHKAVGYGMPGRLVD
GNDAAAVHQVLSEAVARARRGEGPTLVEAVTYRMEAHTNADDATRYRVDSEVEAWKAHDP
VRLLERELTERGLLDDAGIEQAKEAAERMAAALRDRMNADPELTPMDLFTHVYAEQTGQL
REQAAALRAELDAEQDHDEHSAEAGR
NT seq
1161 nt
NT seq
+upstream
nt +downstream
nt
atgacggtccaagagctgcccggcgcggccgcctaccggcccacgccgcccccggcctgg
aagccgatcaccgaccccgccccgctgctcccggacccggagccctaccgggtgctcggt
acggacgcggtcgccgacgtcgaccccgagctgttgctgcggctccacgccgagctggtc
cgcgggcgccgctacaacgcccaggcgaccgcgctgacgaagcagggccgactggcggtc
tacccgtcgagcaccggccaggaggcgtgcgagatcgccgccgccctggtcctggaggag
cgcgactggctcttccccagttaccgcgacacgctggccgccgtcgcacgcggcctggac
ccggtcgaggcgctgaccctgctgcgcggtgaccggcacaccggctacgacccgcgcgag
caccgcatcgccccgctgtgcaccccgctggccacgcagctcccgcacgccgtggggctg
gcgcacgccgcccggctcaagggcgacgacgtggtggcgctcgccatggtcggcgacggc
ggcaccagcgagggcgacttccacgaggcgctgaacttcgcggccgtctggaaggccccg
gtcgtcttcttcgtccagaacaacggcttcgcgatctccgtgccgctggccaagcagacc
gccgccccctcactggcccacaaggccgtcggatacggaatgccgggccgcctcgtcgac
ggcaacgacgccgccgcggtgcaccaggtgctgagcgaggccgtggcccgggcccggcgc
ggcgagggcccgacgctggtcgaggcggtcacctaccgcatggaagcccacaccaacgcc
gacgacgccacccgctaccgggtcgacagcgaggtcgaggcctggaaggcgcacgacccg
gtccggctcctggagcgcgagctgaccgagcgcgggctgctggacgacgcgggcatcgag
caggcgaaggaggccgccgaacgcatggcagccgccctgcgcgaccggatgaacgccgat
ccggagctgaccccgatggacctcttcacccatgtctacgccgagcagaccggccagctc
cgggagcaggccgcggctctgcgcgccgagctggacgccgagcaggaccacgacgagcac
agcgcggaggcaggacgatga
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