Streptomyces sp. CMC78: SCMC78_56740
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Entry
SCMC78_56740 CDS
T11197
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stcm Streptomyces sp. CMC78
Pathway
stcm00300
Lysine biosynthesis
stcm00550
Peptidoglycan biosynthesis
stcm01100
Metabolic pathways
stcm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stcm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SCMC78_56740
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SCMC78_56740
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SCMC78_56740
Enzymes [BR:
stcm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SCMC78_56740
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
E1-E2_ATPase
PhageMin_Tail
DUF561
Motif
Other DBs
NCBI-ProteinID:
BFP55867
UniProt:
A0AB33KTD7
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All DBs
Position
6300262..6301683
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AA seq
473 aa
AA seq
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MITLSLAEIAEIVGGQPHDIPDPAVTVTGPVVIDSREVVPGSLFAAFAGERVDGHDYARR
AVEAGAAAVLAARPVGVPAIVVDDVVGALGALARAVVERLGTSVVALTGSAGKTSTKDLI
AQLLQRHGPTVWTPGSLNNEIGLPLTALSATAETEHLVLEMGARGIGHISYLTELTPPRV
GLVLNVGSAHLGEFGSREAIAQAKGEMVEGLPEDGCAVLNADDPLVRAMASRTKARVLLF
GEAPEADVRGEKVRMTPDGRPAFELHTPTGCSDVTMRLYGEHHVSNALAAAAVAHELGMS
VTEIAEALSEAGTLSRWRMEVTERGDGVTVVNDAYNANPESMRAALRALAAMGQARGADG
GRTWAVLGQMAELGDASLAEHDAVGRLAVRLNVSKLVAVGGREASWLQLGAYNEGSWGEE
SVHVSDAQAAVDLLRSELRPGDVVLVKASRSVGLEKVALALLENSTEGEVAGR
NT seq
1422 nt
NT seq
+upstream
nt +downstream
nt
gtgatcaccctttccctcgccgagatcgccgaaatcgtcggcgggcagccgcacgacata
ccggatccggcagtcaccgtgaccggacccgtcgtcatcgactcccgcgaggtcgtgccc
ggcagcctgttcgccgcgttcgccggcgaacgggtcgacggccacgactacgcccggcgc
gccgtcgaggcgggcgcggcagccgtactggcggcccggcccgtcggcgttccggcgatc
gtcgtggacgacgtcgtcggcgcgctcggagccctcgcccgcgccgtcgtcgaacgcctc
ggcaccagcgtcgtcgcgctcaccggctcggcgggcaagacgtccaccaaggatctgatc
gcgcagctcctccagcgccacggcccgaccgtctggacgcccggctccctcaacaacgag
atcgggctgccgctcaccgccctgagcgccaccgccgagaccgagcacctggtcctggag
atgggcgcccgcggcatcggccacatcagctacctcaccgagctgaccccgccccgggtc
ggcctggtcctcaacgtaggctccgcgcacctcggcgagttcggcagccgggaggccatc
gcccaggccaagggcgagatggtcgagggcctgcccgaggacggctgcgccgtgctcaac
gcggacgacccgctcgtccgcgccatggcctcgcgcaccaaggcccgcgtcctgctcttc
ggagaagccccggaagcggacgtacggggcgagaaggtccggatgacccccgacgggcgg
cccgcgttcgagctccacacacccaccgggtgcagcgacgtgaccatgcgcctgtacggt
gagcaccacgtgtcgaacgcgctcgccgcggccgccgtcgcccatgagttgggcatgtcc
gtgaccgagatcgccgaggcgctctcggaggcgggcaccctctcccgctggcgcatggag
gtcaccgagcgcggggacggtgtgacggttgtcaacgacgcctacaacgcgaaccccgaa
tccatgagagccgcactgcgtgcgctggctgccatgggccaggcccgaggggccgacggg
gggcgcacctgggcggtgctcggtcagatggccgagctcggtgacgcgtcgctcgccgag
cacgacgcggtcggacggctcgccgtccggctcaacgtcagcaagctcgtcgctgtcggg
gggagagaagcctcctggctgcaactgggcgcatataacgagggttcgtggggtgaggag
tcggtgcacgtgtccgacgcacaggcggccgtcgacctgttgcgcagtgaactgcgcccg
ggagacgtcgtgctggtgaaggcgtcccggtcggtcggcctggagaaggtcgccctggca
ctgctggagaactcgaccgagggcgaggtcgccggccgatga
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