Streptococcus pseudopneumoniae: SPPN_08125
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Entry
SPPN_08125 CDS
T01590
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
std
Streptococcus pseudopneumoniae
Pathway
std00300
Lysine biosynthesis
std00550
Peptidoglycan biosynthesis
std01100
Metabolic pathways
std01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
std00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
SPPN_08125
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
SPPN_08125
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
SPPN_08125
Enzymes [BR:
std01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
SPPN_08125
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AEL11051
LinkDB
All DBs
Position
complement(1567159..1568532)
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AA seq
457 aa
AA seq
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MKLTIHEVAQAVRAKNDISIFEDTQLEKAEFDSRLIATGDLFAPLKGARDGHDFIETAFE
NGAAVTLSEKEVANHPYILVDDVLTAFQQLAAYYLEKMAVDVFAVTGSNGKTTTKDMLAH
LLSTTYKTYKTQGNYNNEIGLPYTVLHMPEGTEKLVLEMGQDHLGDIHLLSELAHPKTAI
VTLVGEAHLAFFKDRSEIAKGKMQIADGMVSGSLLLAPADSIVEDYLPTDKKVVRFGPGA
ELEITDLIERKDSLTFKANFLEQALDLPVTGKYNATNAMIASYVVLQEGVSEEQIRQAFQ
NLELTRNRTEWKKAANGADILSDVYNANPTAMKLILETFSAIPANEGGKKIAVLADMKEL
GDQSVQLHNQMILSLSPDVLDTVIFYGEDIAELAKLASQMFPIGHVYYFKKTEDQDQFED
LVKQVKESLGAHDQILLKGSNSMNLAKLVESLATEAK
NT seq
1374 nt
NT seq
+upstream
nt +downstream
nt
atgaaattaacaatccatgaagttgcccaagctgttagggctaaaaatgatatcagcatc
tttgaggacacccagttagagaaagctgagtttgacagtcgtttgattgcgacaggagat
ttatttgcgcccctcaaaggtgcgcgtgacggtcatgactttatcgaaacagcttttgaa
aatggcgctgctgtaaccctgtctgagaaagaggttgcaaatcatccctatattctagta
gatgatgtcttgactgcctttcaacaactagctgcctactatcttgagaaaatggctgtt
gatgtctttgcagttacaggttcaaatggcaagacaacgaccaaggatatgttggcgcac
ttgctatcaacaacctacaaaacctacaaaacacaaggcaattacaataacgagatcggc
cttccctacacagttcttcatatgcctgaaggaacagaaaagttggttttggagatgggg
caggatcacttgggcgatattcatctcttgtctgagttggctcatccaaagacagccatc
gtgaccttggttggagaagcccatttggcctttttcaaagaccgttcggagatcgctaaa
gggaaaatgcaaattgcagatggtatggtatcgggttccttgcttttggcaccagctgac
tccattgtagaggactacttgccaacagataaaaaggtagtccgttttgggccaggagca
gagttggaaattacagacttgattgagcgcaaggacagtctgacctttaaggctaatttc
ttggaacaagccctcgatttgccagtgactggtaagtacaatgccaccaatgctatgatt
gcgtcctatgttgtcctacaagaaggggtttcagaggagcaaattcgtcaggccttccaa
aatcttgaattgacgcgtaatcgtaccgagtggaagaaagcagccaatggagcagatatc
ctatcagatgtgtataatgccaacccaactgctatgaagctgattttagagactttctct
gccatcccagccaatgaaggtggcaaaaaaattgctgtcttggcggatatgaaggaactt
ggtgaccagtctgttcaactccataaccagatgattttgagtctctctccagatgtgctt
gataccgtgattttctatggagaagacattgctgaattagccaaattggccagtcaaatg
ttcccaattggccacgtttactacttcaagaaaacagaagaccaagaccaatttgaagac
ctagtcaagcaggtcaaggaaagtctaggagcccacgaccaaatcctactcaaaggctct
aactctatgaatctagccaagttggtagaaagtttagcaactgaagccaagtga
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