Streptomyces tendae: F3L20_07010
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Entry
F3L20_07010 CDS
T09112
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
stee
Streptomyces tendae
Pathway
stee00290
Valine, leucine and isoleucine biosynthesis
stee00660
C5-Branched dibasic acid metabolism
stee01100
Metabolic pathways
stee01110
Biosynthesis of secondary metabolites
stee01210
2-Oxocarboxylic acid metabolism
stee01230
Biosynthesis of amino acids
Module
stee_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
stee00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
F3L20_07010 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
F3L20_07010 (leuC)
Enzymes [BR:
stee01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
F3L20_07010 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
F3L20_07010 (leuC)
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Motif
Pfam:
Aconitase
DUF4946
Motif
Other DBs
NCBI-ProteinID:
QER85660
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Position
1489316..1490746
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AA seq
476 aa
AA seq
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MGRTLAEKVWDDHVVRRAEGEPDLLFIDLHLLHEVTSPQAFDGLRKNGRRVRRLDLTIAT
EDHNTPTLDIDKPIADPVSRVQLETLRKNCAEFGVRLHPLGDVEQGVVHVVGPQLGLTQP
GMTVVCGDSHTSTHGAFGGLAFGIGTSQVEHVLATQTLPMARPKTMAITVNGELPEGVTA
KDLILAIIARIGTGGGQGYVLEYRGEAIEKLSMEARMTICNMSIEAGARAGMIAPDETTF
AYLEGRPHAPKGEDWDAAVAYWKTLRSDDDAEFDAEVVIEASELSPFVTWGTNPGQGAPL
SASVPDPASYEDASERFAAEKALEYMGLEAGQTLRSINVDTVFVGSCTNGRIEDLRAAAD
VIKGRKVADGVRMLVVPGSARVGLQAVSEGLDVVFKEAGAEWRHAGCSMCLGMNPDQLAP
GERSASTSNRNFEGRQGKGGRTHLVSPQVAAATAVLGHLASPADLAAADDRTPAGV
NT seq
1431 nt
NT seq
+upstream
nt +downstream
nt
atgggtaggacactcgcggagaaggtctgggacgaccacgtcgtccggcgcgccgagggc
gagcccgacctcctcttcatcgatctgcacctgctgcacgaggtgaccagcccccaggcc
ttcgacggcctccgtaagaacggccgccgggtgcgccgtctcgacctcaccatcgcgacc
gaggaccacaacacccccaccctcgacatcgacaagcccatcgccgacccggtctcccgg
gtccagctggagacgctgcgcaagaactgcgcggagttcggcgtccggctgcacccgctg
ggcgacgtcgagcagggcgtcgtacacgtcgtcggtccgcagctgggtctgacccagccc
ggcatgaccgtggtctgcggcgactcgcacacctccacgcacggcgccttcggcggactg
gccttcggcatcggcacctcccaggtcgagcacgtcctggccacccagacgctgccgatg
gcccgccccaagaccatggcgatcacggtcaacggtgagctgcccgagggcgtcacggcc
aaggacctgatcctcgcgatcatcgccaggatcggtacgggcggcggccagggctacgtc
ctggagtaccgcggcgaggccatcgagaagctctcgatggaggcccgcatgaccatctgc
aacatgtcgatcgaggccggcgcccgcgcgggcatgatcgcccccgacgagacgacgttc
gcctacctcgagggccgtccgcacgccccgaagggcgaggactgggacgccgccgtcgcc
tactggaagacgctgaggtccgacgacgacgccgagttcgacgccgaggtcgtcatcgag
gcctccgaactgtcgccgttcgtcacctggggcaccaatcccgggcagggcgccccgctc
tccgcgtcggtccccgacccggcctcgtacgaggacgcctcggagcggttcgccgccgaa
aaggcgctggagtacatggggttggaggccggccagacgctgcgctccatcaacgtggac
accgtcttcgtaggttcctgcaccaacggccgcatcgaggacctgcgcgccgccgccgac
gtcatcaagggccgcaaagtcgccgacggcgtacggatgctggtcgtccccggctccgcg
cgggtcggtctccaggccgtctccgagggcctggacgtggtcttcaaggaggcaggcgcc
gagtggcggcacgcgggctgctcgatgtgcctgggcatgaaccccgaccagctcgccccc
ggtgagcgctccgcctccacctccaaccgcaacttcgagggacggcagggcaagggcggc
cgtacccacctggtgtccccgcaggtcgccgccgccaccgcggtgctcgggcacctggcc
tccccggccgacctcgccgccgccgacgaccgcacgcccgctggagtctga
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