Streptomyces tendae: F3L20_26440
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Entry
F3L20_26440 CDS
T09112
Name
(GenBank) bifunctional folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stee
Streptomyces tendae
Pathway
stee00790
Folate biosynthesis
stee01100
Metabolic pathways
stee01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stee00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
F3L20_26440
Enzymes [BR:
stee01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
F3L20_26440
6.3.2.17 tetrahydrofolate synthase
F3L20_26440
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
QER88931
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Position
complement(5754057..5755577)
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AA seq
506 aa
AA seq
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MSERPDSAGPDPDDTFDEFAELVEEETRRDPDLAVIEAGSRTLRTQGGPPQADVPARPAD
PEVDKALREVEAELATRWGETKLEPSVARIAALMDVLGEPQRAYPSIHITGTNGKTSTAR
MIEALLGAFDLRTGRYTSPHVQSVTERISLDGAPVSAERFIETYQDIKPYVEMVDASQEY
RLSFFEVLTGMAYAAFADAPVDVAVVEVGMGGTWDATNVIDAGVAVVTPIDLDHTDRLGS
TPAEIATEKSGIVKQDATVIMAQQPVDAAQVLLKKAVEVGATVAREGLEFGVLDRQVAVG
GQLMTLRGLGGEYTEVYLPLHGAHQAHNAAVALAAVEAFFGIGSQQAQPLDIDTVRKAFA
SVASPGRMEVVRRSPTVVLDAAHNPAGARAAADTIGEAFQFSNLIGVVGASGDKNVRGLL
EAFEPVFAEVVVTQNTSHRAMDADELAAVAVEVFGEDRVQVEPRLPDALEAAITLAEEEG
EFAGGGVLVTGSVITVGEARLLLGKG
NT seq
1521 nt
NT seq
+upstream
nt +downstream
nt
gtgagcgagcgcccagattcagcaggtcccgacccggacgacaccttcgacgagttcgcg
gagctcgtggaggaggagacccgccgcgaccccgacctggcggtgatcgaggccggcagc
cgtacgctgcgcacccagggcgggccgccgcaggcggacgtccccgcgcgcccggccgac
cccgaggtcgacaaggccctgcgtgaggtggaggcggaactcgccacccgctggggcgag
accaagctggagccgtcggtggcccgcatcgccgccctgatggacgtcctcggggaaccg
cagcgcgcgtacccctcgatccacatcaccggcaccaacggcaagacgtccacggcccgc
atgatcgaggccctgctcggcgccttcgacctgcgcaccggccgctacacctccccgcac
gtccagtccgtcaccgagcggatcagcctcgacggggcaccggtctccgccgagcggttc
atcgagacgtaccaggacatcaagccgtacgtggagatggtcgacgcctcccaggagtac
cggctgtccttcttcgaggtgctgaccggcatggcgtacgccgccttcgccgacgcgccc
gtggacgtggcggtcgtcgaggtcggcatgggcggcacctgggacgcgacgaacgtgatc
gacgccggtgtcgccgtggtgacgccgatcgacctggaccacaccgaccggctgggctcc
acgcccgccgagatcgccaccgagaagtccggcatcgtcaagcaggacgcgacggtgatc
atggcgcagcagccggtggacgcggcgcaggtgctgctgaagaaggccgtcgaggtgggc
gccaccgtggcccgcgagggtctggagttcggcgtcctggaccggcaggtcgccgtcggc
ggccagctgatgacgctgcgcgggctgggcggcgagtacaccgaggtgtacctgccgctg
cacggcgcgcaccaggcgcacaacgcggcggtggccctcgccgccgtcgaggcgttcttc
ggcatcggttcccagcaggcccagccgctcgacatcgacaccgtgcgcaaggcgttcgcc
tccgtcgcctcgccgggccgcatggaggtcgtgcgcaggtcgccgaccgtcgtgctggac
gccgcccacaacccggccggcgcgcgggcggcggccgacacgatcggggaggccttccag
ttcagcaacctcatcggcgtggtcggcgcgagcggcgacaagaacgtgcgcgggctgctc
gaggcgttcgagccggtcttcgccgaggtcgtcgtcacccagaacaccagccaccgcgcg
atggacgccgacgaactggccgccgtcgccgtcgaggtgttcggggaggaccgcgtgcag
gtcgagccgcggctgccggacgccctggaggccgcgatcacgctggccgaggaggagggc
gagttcgccggcggcggtgtgctcgtcaccggttccgtcatcaccgtcggcgaggcccga
ctgctcctggggaagggctga
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