Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_0656
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Entry
MGAS15252_0656 CDS
T01794
Symbol
folC.1
Name
(GenBank) dihydrofolate synthase/folylpolyglutamate synthase protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00790
Folate biosynthesis
stg01100
Metabolic pathways
stg01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MGAS15252_0656 (folC.1)
Enzymes [BR:
stg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MGAS15252_0656 (folC.1)
6.3.2.17 tetrahydrofolate synthase
MGAS15252_0656 (folC.1)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AFC66005
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Position
complement(635421..636689)
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AA seq
422 aa
AA seq
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MTTYDSISWIHTFKANGRKTDLARMAWLLEALGRPQDKFPAIHVVGTNGKGSVTAYLQHI
LSTSGYQVGTFTSPFIISFHDRICLNGQPISDLELAQCVSVIRPILTKMSLETNWDRPTE
FELVTLIMFCYFANLKPVDIAIIEAGIGGKTDATNVFHALAVVCPSISFDHQERLGYSLA
EIAHQKAEVIKAKEPVIIGQLEQEASQVFQQVTQKAGSRLYQLGKDFLLNPSEKTFSFQH
DNLNLTKLRLKLLGQHQKANACLAIMTAQLLRKSFPKISPKTIQKGIEATTWPGRSEFIQ
PNLLLDGAHNPDSIAKLKSLLQEEFPKRPIHILFAGLKRKPLADLLAQLDTFEVSVTTFD
FPEANLLEDYPDKYPQVKDYRDWLQGSVTSDELFVVTGSLYFISEVRQYCLSNANIFKNI
FP
NT seq
1269 nt
NT seq
+upstream
nt +downstream
nt
atgactacctatgatagcatttcctggattcatacctttaaggctaatggtcgcaagacc
gatttggccagaatggcttggttacttgaggcactaggccggccacaagacaaattccct
gctattcacgttgttggaactaacggcaaaggctctgtgacagcctacttacagcatatc
ctgtcaacttctggttatcaggtcggaacctttacatctccttttattatctcttttcac
gatcggatttgccttaatggccagcccatttcagacctagaattggcgcaatgtgtgagc
gtgattagacccattctcactaaaatgtcccttgaaacaaattgggatagacctaccgag
tttgagttagtgactctcataatgttttgctactttgccaatcttaaacctgttgatatt
gccattattgaggcagggattggtgggaaaaccgacgcaaccaatgtttttcatgctctg
gccgtcgtatgcccttctattagttttgatcaccaagaacgtttaggttatagcctagca
gaaattgctcaccaaaaagcagaagttatcaaagctaaagaacccgttattatcggtcaa
cttgagcaggaggctagtcaagtctttcaacaagttacccaaaaagccggttcacgctta
tatcaattaggaaaagattttttgctcaatccttcagaaaagacgttttcctttcaacac
gataacttgaatttaactaaactccgtctcaaactattaggtcaacatcaaaaagcgaat
gcctgtttagccattatgacagctcaattacttagaaaatcctttcctaaaatatctcca
aaaacgattcaaaaaggaattgaggcaacaacttggcctggccggtccgaatttattcaa
cctaatcttctattagacggcgctcacaatccagattccattgctaaattaaagtcttta
ctgcaagaagaatttcccaaacgtcctattcatatcctctttgcaggtctcaaacgtaag
cctttagccgacttgctggctcaactagatacttttgaagtatctgtcacgacttttgat
ttccctgaagcaaatcttttagaggattatcctgataaatacccacaggtaaaagattac
agagactggttacaaggttccgtaacatctgatgaactctttgttgttacagggtcactt
tattttatctccgaggtaaggcaatattgtctgagcaacgcaaatatctttaaaaacata
ttcccctaa
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