Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_0822
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Entry
MGAS15252_0822 CDS
T01794
Symbol
folC.2
Name
(GenBank) dihydrofolate synthase/folylpolyglutamate synthase protein FolC
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00790
Folate biosynthesis
stg01100
Metabolic pathways
stg01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
MGAS15252_0822 (folC.2)
Enzymes [BR:
stg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
MGAS15252_0822 (folC.2)
6.3.2.17 tetrahydrofolate synthase
MGAS15252_0822 (folC.2)
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Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
AFC66167
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Position
807951..809228
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AA seq
425 aa
AA seq
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MTYEETLEWIHDHLVFGIKPGLKRMLWVLGQLGNPQKNVKGVHIVGTNGKGSTVNHLQHI
FTTAGYEVGTFTSPYIMDFKERISINGRMISEKDLVIAANRIRPLTERLVQETDFGEVTE
FEVITLIMFLYFGDMHPVDIAIIEAGLGGLYDSTNVFQAMVVVCPSIGLDHQAILGETYA
DIAAQKAGVLEGGETLVFAVENPSAREVFLTKADQVGASIWEWQEQFQMAENASGYRFTS
PLGVISDIHIAMPGHHQVSNAALAIMTCLTLKDRYPRLTSDHIREGLANSLWLGRTELLA
PNLMIDGAHNNESVAALVAVLKNNYNDKKLHILFGAIDTKPIADMLVALEQIGDLQVTGF
HYPNAYPLEKYPERFGRVADFKDFLALRKHAKADDFFVITGSLYFISEIRRYWKKHIEKN
VLLTH
NT seq
1278 nt
NT seq
+upstream
nt +downstream
nt
atgacttatgaagagactctagaatggattcatgatcacttagttttcggcatcaagcca
ggcttaaaacgtatgctttgggttcttggacagttaggaaatccccagaaaaatgtcaag
ggagtgcatatcgttggaactaacggaaaaggttccacggtcaatcatttacaacatatc
tttacgacagctggttatgaagtggggacctttacctctccttacattatggatttcaaa
gaacgtattagcataaatggtcgaatgatttcagaaaaagatttggttattgctgctaat
cgtattcgtcctttgacagagcgtctagttcaagagactgattttggagaggtaactgaa
tttgaagtgattactttgatcatgttcctctattttggagacatgcatcctgtagatatt
gctattattgaagcaggccttggcggtctttatgattcgaccaatgtttttcaagcaatg
gttgtggtctgtccctcaattggtttagatcaccaagctattttgggagagacttacgct
gatattgccgcccaaaaagctggtgttttagaagggggcgagacccttgtttttgccgtt
gaaaacccgtcagctcgagaggtttttttaacaaaagctgatcaggttggtgcttcaatc
tgggaatggcaagagcagtttcaaatggctgagaacgcatctggctatcgttttactagt
cctttaggagttatttcagatattcacatcgctatgccaggacaccaccaagtgtctaat
gcagctttagctattatgacttgcttaaccttgaaagaccgctatcctaggctaacttca
gatcatataagggaaggtctggcaaatagtttgtggctaggccgtaccgaattattagca
ccaaatctaatgattgatggggctcataacaatgaaagcgttgctgctttggtagccgtc
ttaaaaaataactacaatgataaaaagcttcatattttgtttggtgcgatcgacaccaag
cctattgcggatatgttggttgctcttgagcaaataggtgacttgcaggttactggcttt
cattaccctaacgcctatccattggaaaaatacccagaacgttttggtagggttgctgat
ttcaaagatttcttggccctgcgtaagcatgctaaagcagatgactttttcgtgattaca
gggtcactatattttatttcagaaattagacggtattggaaaaaacatattgaaaaaaac
gttcttttaacccattaa
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