Streptococcus pyogenes MGAS15252 (serotype M59): MGAS15252_1597
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Entry
MGAS15252_1597 CDS
T01794
Symbol
pbp2A
Name
(GenBank) multimodular transpeptidase-transglycosylase Pbp2A
KO
K12555
penicillin-binding protein 2A [EC:
2.4.99.28
3.4.16.4
]
Organism
stg
Streptococcus pyogenes MGAS15252 (serotype M59)
Pathway
stg00550
Peptidoglycan biosynthesis
stg01100
Metabolic pathways
stg01501
beta-Lactam resistance
Brite
KEGG Orthology (KO) [BR:
stg00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
MGAS15252_1597 (pbp2A)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01501 beta-Lactam resistance
MGAS15252_1597 (pbp2A)
09180 Brite Hierarchies
09181 Protein families: metabolism
01003 Glycosyltransferases [BR:
stg01003
]
MGAS15252_1597 (pbp2A)
01011 Peptidoglycan biosynthesis and degradation proteins [BR:
stg01011
]
MGAS15252_1597 (pbp2A)
Enzymes [BR:
stg01000
]
2. Transferases
2.4 Glycosyltransferases
2.4.99 Transferring other glycosyl groups
2.4.99.28 peptidoglycan glycosyltransferase
MGAS15252_1597 (pbp2A)
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.16 Serine-type carboxypeptidases
3.4.16.4 serine-type D-Ala-D-Ala carboxypeptidase
MGAS15252_1597 (pbp2A)
Glycosyltransferases [BR:
stg01003
]
Polysaccharide
Bacterial polysaccharide (excluding LPS)
MGAS15252_1597 (pbp2A)
Peptidoglycan biosynthesis and degradation proteins [BR:
stg01011
]
Peptidoglycan biosynthesis and degradation
Glycosyltransferase/DD-Transpeptidase (Class A PBP)
MGAS15252_1597 (pbp2A)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Transgly
Transpeptidase
Motif
Other DBs
NCBI-ProteinID:
AFC66908
LinkDB
All DBs
Position
complement(1601434..1603770)
Genome browser
AA seq
778 aa
AA seq
DB search
MRFLELLQKKFFPKAYQEKQFLMHQKARLTPQHNQKQYSPNANHLDSSATKNSEQDPAIA
LQRSRAYEGSPKSRPAWLQKLEAVLPSPQHPIRRFWRRYHIGKLLMILIGTLVLLLGSYL
FYLSKTAKVSDLQDALKATTVIYDHKGEYAGSLSGQKGSYVELNAISDDLENAVIATEDR
TFYSNSGINLKRFLLAVVTAGRFGGGSTITQQLAKNAYLSQDQTIKRKAREFFLALELTK
KYSKKDILTMYLNNSYFGNGVWGVEDASQKYFGTTAANLTLDEAATLAGMLKGPEIYNPY
HSLKNATHRRDTVLGAMVDAKKITQTKAQQARAVGLKNRLADTYVGKTDDYKYPSYFDAV
ISEAIATYGLSEKDIVNNGYKVYTELDQNYQTGMQTTFNNDELFPVSAYDGSSAQAASVA
LDPKTGGVRGLIGRVNSSENPTFRSFNYATQAKRSPASTIKPLVVYAPAVASGWSIEKEL
PNTVQDFDGYQPHNYGNYESEDVPMYQALANSYNIPAVSTLNDIGIDKAFTYGKTFGLDM
SSAKKELGVALGGNVTTNPLEMAQAYAAFANNGVIHPAHLINRIENARGEVLKTFTDKAK
RVVSQSVADKMTAMMLGTFSNGTAVNANVYGYTLAGKTGTTETNFNPDLAGDQWVIGYTP
DVVISQWVGFNQTDENHYLTDSSAGTASAIFSTQASYILPYTKGSQFHVDNAYAQNGISA
VYGVNETGNQSGVDTQSIIDGLRKSAQEASQSLSKAVDQSGLRDKAQSIWKEIVDYFR
NT seq
2337 nt
NT seq
+upstream
nt +downstream
nt
atgagatttctagaacttttacaaaagaaattttttcctaaagcatatcaggaaaaacaa
ttcttaatgcatcaaaaagcgcgtttaacgccacaacacaatcaaaagcagtattcgcca
aatgccaatcatttggactcatcagctaccaaaaactcagaacaagaccctgcaatagct
ctgcaacgcagtagagcctatgaaggaagccctaaaagtcggcccgcttggttgcaaaag
ctggaagctgttttgccgtctcctcaacatccaattcggcgtttttggcgccgctatcac
atcggaaaactgctaatgattctgattggaactcttgtcttactcttaggatcatacttg
ttttatttatcaaaaacagctaaagtatctgatttacaagatgccttgaaggctacaacg
gttatttatgatcacaaaggagagtatgcaggcagtttatctggtcaaaaagggagttat
gttgagctcaacgctatttcagatgatcttgagaatgctgttattgccactgaggatagg
actttttacagtaatagcggtattaatcttaaacgcttcttattggcggtagttacggcg
ggccgctttggaggtggctcaacgattacacagcaactggctaaaaatgcttatctctca
caagatcagacaattaaacgaaaggcccgagagttttttttggcgttagagttgaccaaa
aaatacagtaaaaaagatattcttactatgtaccttaacaactcctactttggaaatgga
gtttggggagttgaagatgccagtcaaaaatattttggaaccacagctgctaacttaaca
ctggatgaagctgccacattagcaggtatgctcaaaggacctgaaatatataacccttac
cattctctaaaaaatgctactcaccgtagagatactgttttaggagcgatggttgatgcc
aaaaagattacccaaacaaaagctcagcaagctagagcagtagggctaaaaaatcgctta
gctgatacttatgttggtaagacagatgactacaaatacccatcctactttgatgctgtt
attagtgaagcaatagcaacttatggtctttcagaaaaagacattgttaataatggatac
aaagtttacaccgagctagatcaaaattaccaaactggcatgcagacgacttttaacaac
gatgaactatttcctgtttcagcttatgacggtagctctgctcaagcagctagtgttgct
ttagatcctaaaacaggaggtgttagaggtctgattggtcgtgtgaatagtagtgaaaat
ccgactttcagaagttttaactatgcgactcaagcaaaacgtagtcccgcatcaacaatc
aaaccactcgtggtttacgcgccagccgttgcttcaggatggtcaattgaaaaagaacta
ccaaataccgttcaagatttcgatggctatcagccacataattatggaaattatgaatca
gaagatgttcctatgtatcaagcattagcaaactcttataatattccagcagtttctaca
ttgaacgatatcggaatcgataaagcctttacctatggtaaaacatttgggttagatatg
agctctgccaaaaaagagttgggggtagctttaggtggcaacgtgacaaccaatccattg
gagatggctcaggcatatgctgcctttgccaataatggagtaatccatcctgcgcacttg
attaaccggattgaaaatgccaggggtgaagtgcttaaaacctttactgataaggctaaa
cgtgttgtcagccagtctgttgcagataagatgacagccatgatgctaggtaccttttca
aatggaacagcagtcaatgctaacgtatatggctatacactagctggtaaaacagggacg
acagaaaccaacttcaatcccgacttagcaggcgatcagtgggttattggttatacacca
gatgttgttattagtcaatgggtaggatttaatcagaccgatgaaaatcattatctaacg
gattcaagtgcaggcacggcctcagctatttttagcactcaggcatcttacattttgcct
tataccaagggcagccaatttcatgtagataatgcctacgctcaaaatggtatttcagct
gtttatggagtcaatgaaacaggtaatcaatcaggagttgacactcaatctattattgat
ggtttaagaaaatcagcacaagaagcttcgcaatcactatcaaaagcagtcgatcagtca
gggttacgtgataaagcccaatctatttggaaagagattgttgactattttagatag
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