Symbiobacterium thermophilum: STH1207
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Entry
STH1207 CDS
T00196
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
sth
Symbiobacterium thermophilum
Pathway
sth00300
Lysine biosynthesis
sth00550
Peptidoglycan biosynthesis
sth01100
Metabolic pathways
sth01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
sth00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
STH1207
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
STH1207
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
STH1207
Enzymes [BR:
sth01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
STH1207
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Paralog
Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
BAD40192
UniProt:
Q67Q51
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Position
1343407..1344972
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AA seq
521 aa
AA seq
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MTQLFTAAEIAALTGGRLAAGDPNAGVSGIAWDSRLVRPGDCFVALAGERADGHDFAAQA
AARGAACVLAARPVPAGDAAVVVCPDPLLGLGRLGLALRSRHPHLRVVGITGSVGKTTTK
EMTAAVLAERFRVFRTEGNLNSEVGLPASLAGLTDEHEAAVLEMGMRAPGEIAYLASIAR
PQVGVVTNVGITHLELLGTQENIALAKSELVRALPPDGVAVLNADDPRVRAMAAATPARV
WFYGLTAREAADDAAAAPVATGTAGEAGTPGGRVVGWVTAENARPDGPMAQRFRLVCHLG
EADVRLPAPGPHNLLNALAAAAVGLSQGLDLEAVARGLSLFRNAGNRLRLVEAGGVRILD
DTYNAAPASVIAALEVMRGFAGPEGRCVAVLGDMYELGALEVEGHRQVGMVAARLTDELV
AVGQLGRHIAEGARAALAGAGGGSAGAGFRGGEGPPEGQGPVAGGGTRLREVHHVPDNAG
AIAWLKERLRPGDTVLVKGSRGMKMEEIVQALAAHLDRPQP
NT seq
1566 nt
NT seq
+upstream
nt +downstream
nt
ttgacacagctgtttaccgccgccgagatcgcggcgctcaccggcggccgcctggccgcc
ggcgatcccaacgcaggggtgagcggcatcgcctgggacagccggctggtccggcccggc
gactgcttcgtggccctggcgggcgaacgggcggacgggcacgacttcgcggcgcaggcg
gccgcccggggagcggcgtgcgtcctggcggcccggccggtgccggcaggggatgcggcc
gtcgtcgtctgtccggacccgctgctggggctggggcggctggggctggccctgcgcagc
cgccatccgcacctgcgggtcgtgggcatcaccggatcggtgggcaagaccaccaccaag
gagatgaccgcggcggtcctggctgagcggttccgggtcttccggaccgaaggaaacctg
aattcggaggtggggctgccggcgtcgctcgccggcctcaccgacgagcacgaggcggcg
gtgctggagatgggcatgcgcgccccgggcgagatcgcctatctggcctccatcgcgcgg
ccgcaggtgggggtggtcaccaacgtgggcatcacccacctggagctcctgggcacgcag
gagaacatcgcgctggccaagtccgaactggtgcgggccttgccgccggacggcgtcgcg
gtgctgaacgcggacgacccccgggtgcgggccatggcggcggccacgcccgcccgggtg
tggttctacggactcacggcgcgggaggcggccgacgatgcggcggctgcgccggtggcg
acgggaacggccggcgaggcaggcacgccggggggccgcgtggtcggatgggtgacggca
gagaacgcccggcccgacggccccatggcccagcggttccggctggtctgccacctgggt
gaggcggacgtccgcctgcccgcgccggggccccacaacctgctcaacgccctggccgcg
gcagccgtggggctgtcccagggcctggacctggaggcggtggcccgggggctctccctg
ttccggaacgccgggaaccggctgcggctggtggaggccggcggcgtccgcatcctggac
gacacgtacaacgccgctccggcttccgtcatcgccgcactggaggtcatgcggggcttc
gccggcccggagggccgctgcgtcgccgtgctgggcgatatgtacgagctgggcgccctg
gaggtggaagggcaccggcaggtggggatggtggccgcccggctgaccgacgaactggtg
gccgtggggcagcttggccgccacatcgccgagggcgcccgggcggcgctggccggcgcg
ggcggcggttcggccggggcgggcttccggggcggggaagggccgccggaggggcagggg
cccgtcgccggcggggggacccggctccgggaggtgcaccacgtgcccgacaacgccggg
gcgatcgcctggctgaaggagcggctgcgccccggggatacggtgctggtgaagggctcc
cgcggcatgaaaatggaagagatcgttcaggcgctcgcagcacacctggaccggcctcag
ccgtag
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