KEGG   Symbiobacterium thermophilum: STH414
Entry
STH414            CDS       T00196                                 
Name
(GenBank) pyruvate dehydrogenase E3
  KO
K00382  dihydrolipoyl dehydrogenase [EC:1.8.1.4]
Organism
sth  Symbiobacterium thermophilum
Pathway
sth00010  Glycolysis / Gluconeogenesis
sth00020  Citrate cycle (TCA cycle)
sth00260  Glycine, serine and threonine metabolism
sth00280  Valine, leucine and isoleucine degradation
sth00310  Lysine degradation
sth00380  Tryptophan metabolism
sth00620  Pyruvate metabolism
sth00630  Glyoxylate and dicarboxylate metabolism
sth00640  Propanoate metabolism
sth00670  One carbon pool by folate
sth00785  Lipoic acid metabolism
sth01100  Metabolic pathways
sth01110  Biosynthesis of secondary metabolites
sth01120  Microbial metabolism in diverse environments
sth01200  Carbon metabolism
sth01210  2-Oxocarboxylic acid metabolism
sth01240  Biosynthesis of cofactors
Module
sth_M00009  Citrate cycle (TCA cycle, Krebs cycle)
sth_M00011  Citrate cycle, second carbon oxidation, 2-oxoglutarate => oxaloacetate
sth_M00307  Pyruvate oxidation, pyruvate => acetyl-CoA
sth_M00621  Glycine cleavage system
Brite
KEGG Orthology (KO) [BR:sth00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    STH414
   00020 Citrate cycle (TCA cycle)
    STH414
   00620 Pyruvate metabolism
    STH414
   00630 Glyoxylate and dicarboxylate metabolism
    STH414
   00640 Propanoate metabolism
    STH414
  09105 Amino acid metabolism
   00260 Glycine, serine and threonine metabolism
    STH414
   00280 Valine, leucine and isoleucine degradation
    STH414
   00310 Lysine degradation
    STH414
   00380 Tryptophan metabolism
    STH414
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    STH414
   00670 One carbon pool by folate
    STH414
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:sth04147]
    STH414
Enzymes [BR:sth01000]
 1. Oxidoreductases
  1.8  Acting on a sulfur group of donors
   1.8.1  With NAD+ or NADP+ as acceptor
    1.8.1.4  dihydrolipoyl dehydrogenase
     STH414
Exosome [BR:sth04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   STH414
SSDB
Motif
Pfam: Pyr_redox_2 Pyr_redox_dim Pyr_redox Pyr_redox_3 GIDA FAD_oxidored DAO HI0933_like FAD_binding_2 NAD_binding_8 AlaDh_PNT_C FAD_binding_3 Lycopene_cycl UDPG_MGDP_dh_N Thi4 Lys_Orn_oxgnase Trp_halogenase
Other DBs
NCBI-ProteinID: BAD39399
UniProt: Q67SE4
LinkDB
Position
450110..451522
AA seq 470 aa
MGSIKTGTDVVVIGAGPGGYVAAQRASQLGLDVTLIEREELGGTCLNHGCIPSKALISVG
DLLYKVNNAAERGLVVKGSVEVDFAKTQEWKETKVIKRLTSGVASLMKAGQVEVVKGTAR
FTDPHSLEVELNDGGTAAYTFKHAIIATGSTAVNPSFFPLDGENVVDARGALAFREIPPR
FVVVGGGYIGVELGIAYAKLGSKVTIVEATGQLLPGTDPDLVNVLMRRLRRLGVTVMLNA
RASGGLQNGKVKVQDGEGKVHEIEADKVLVSVGRVPYTEGLHLDKAGVRVDEKGFIPVDE
QMRTNVPHIYAIGDVCSPVMLAHKASAQGRVAAEAIAGRPSAADWQTVPAVIFTDPEIAY
VGLTEAQAREKGYDPVVSRYNFAAVGRALTMGESDGMVKLVGDRQSGLLLGAQMVGPEVS
ELIGEIALAIEMGAQMEDVALTPHYHPTLSEGILEAALSWMHSIEKAGRK
NT seq 1413 nt   +upstreamnt  +downstreamnt
atgggttccatcaagaccggcaccgatgtggtggtcatcggtgcggggcccgggggatac
gtggccgcccagcgggcgtcgcagctgggcctggacgtcactctgatcgaacgcgaggag
ctgggcgggacgtgcctgaaccatggctgcatcccgtccaaggccctgatctccgttggc
gacctgctctacaaggtcaacaacgccgccgaacgggggctggtggtcaagggcagcgtc
gaggtcgacttcgccaagacgcaggagtggaaggagaccaaggtaatcaagcggctcacc
tcgggcgtggcctcgctgatgaaggcggggcaggtggaggtggtgaagggcacggcccgc
ttcaccgacccccactccctggaggtggagctgaacgacggtggcacggccgcgtacacc
ttcaagcacgcgatcatcgcgacgggctccacggccgtcaacccgtccttcttccccctg
gacggggagaacgtcgtcgacgcccggggcgccctggcgttccgggagatcccgccccgg
ttcgtggtggtgggcggcggctacatcggtgtggaactgggcatcgcctacgccaagctc
gggtcgaaggtgacgattgtcgaggcgaccggccagctcctgcccggcaccgaccctgac
ctggtgaacgtgctgatgcgccggctcaggcggctcggcgtgacggtcatgctcaacgcc
cgggcgtcgggcggcctgcagaacggcaaggtgaaggtgcaggacggtgagggcaaggtc
cacgagatcgaggcggacaaggtgctcgtctccgtcggccgggtgccctacaccgagggg
ctgcacctggacaaggccggcgtccgggtcgacgagaagggcttcatcccggtggacgag
cagatgcggaccaacgtcccgcacatctacgccatcggcgacgtgtgctcgccggtgatg
ctggcgcacaaggccagcgcccagggccgggtggctgccgaggccatcgccgggcggccg
tccgcggccgactggcagacggtgcccgcggtgatcttcaccgacccggagatcgcctac
gtggggcttacggaggcgcaggcccgggagaagggctacgaccccgtcgtttcccggtac
aacttcgccgccgtgggccgggcgctcaccatgggcgagtccgacggcatggtgaagctg
gtgggcgaccggcagagcggcctcctgctgggggcgcagatggtcggcccggaggtgtcg
gagctgatcggcgagatcgccctcgcgatcgagatgggcgcccagatggaggacgtggcg
ctgacgccccattaccacccgacactgtcggaaggcatcctggaggcggcgctctcctgg
atgcacagcatcgaaaaagccgggcgcaagtag

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