KEGG   Symbiobacterium thermophilum: STH512
Entry
STH512            CDS       T00196                                 
Name
(GenBank) D-alanine--D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
sth  Symbiobacterium thermophilum
Pathway
sth00470  D-Amino acid metabolism
sth00550  Peptidoglycan biosynthesis
sth01100  Metabolic pathways
sth01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:sth00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    STH512
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    STH512
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    STH512
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:sth01011]
    STH512
Enzymes [BR:sth01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     STH512
Peptidoglycan biosynthesis and degradation proteins [BR:sth01011]
 Precursor biosynthesis
  Amino acid ligase
   STH512
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_4 ATP-grasp_3
Other DBs
NCBI-ProteinID: BAD39497
UniProt: Q67S46
LinkDB
Position
552572..553672
AA seq 366 aa
MCAKTRVYLLFGGRSGEHEVSLMSARNVLEALDRSKYEVIPVGITKEGRWLQVGDPLRAL
TEGVAAAGGRPVGLLGDPSYSGPVPLSDGLRPAAHDGPVVFFPVLHGTYGEDGTIQGLLE
MANVPYVGCGVLASSVAMDKGVAKALFRQAGLEVGPYRVYLRRDWERHPEQIRADVSAHL
RYPVFVKPANLGSSVGITKVKRPEDLDRAMDEAARFDRRIIVEQGIDAREIEVAVLGNDD
PIASVPGEILPGAEFYDYTDKYFSGASQTRIPADLPDDLVEEFRRQAVVAFKAIDGSGMA
RVDFFLERGTNRIFINEVNTIPGFTNISMYPKLWEASGIGYGELLDRLIQLALERHADKN
RNATSV
NT seq 1101 nt   +upstreamnt  +downstreamnt
atgtgcgcgaagacccgcgtttacctgcttttcggcggccgatccggcgagcacgaggtg
tcgctgatgtcggccaggaacgtgctggaggccctggaccggagcaagtatgaggtcatc
cccgtcggcatcaccaaggagggtcgctggctccaggtgggcgacccgctccgggccctg
accgagggggtggcggcggcgggcggccggccggtggggctcctgggcgacccgtcgtac
tccggtccggttcccctgtccgacgggctcaggcctgcggcccacgacgggcccgtggtc
tttttcccggtgctgcacggtacatacggcgaggacggcacgatccaggggctgttggag
atggccaacgtgccctacgtgggctgcggcgtgctggcgtccagcgtcgccatggacaag
ggcgtggccaaggcgctcttccgccaggccggcctcgaggtgggcccctaccgggtctac
ctccggcgcgactgggagcgccaccccgagcagatccgggcggacgtctcagcgcacctc
cgctacccggtgttcgtcaagccggccaacctgggctcgtcggtgggcatcaccaaggtg
aagcggccggaggacctggaccgggccatggatgaggccgcccgctttgaccggcggatc
atcgtcgagcagggcatcgacgcgcgggagatcgaggtcgccgttctgggcaacgacgac
cccatcgcctccgtccccggcgagatcctgccgggggccgagttctacgattacaccgac
aagtacttcagcggcgcgtcccagacccggatcccggccgaccttcccgacgacctggtc
gaggagttccggcgccaggcggtggtggcgttcaaggccatcgacggctccggcatggcc
cgcgtggacttcttcctggaacggggcaccaaccgcatcttcatcaacgaggtgaacacc
attcccgggttcaccaacatctccatgtaccccaagctctgggaggcctcgggcatcggt
tacggcgagctgctggaccggctgatccagctcgccctggagcggcatgccgacaaaaac
cgaaatgccacctcggtttag

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