Sphingobacterium thalpophilum: NCTC11429_01769
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Entry
NCTC11429_01769 CDS
T06778
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
stha
Sphingobacterium thalpophilum
Pathway
stha00300
Lysine biosynthesis
stha00550
Peptidoglycan biosynthesis
stha01100
Metabolic pathways
stha01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
stha00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
NCTC11429_01769 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
NCTC11429_01769 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
NCTC11429_01769 (murF)
Enzymes [BR:
stha01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
NCTC11429_01769 (murF)
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
VTR36855
UniProt:
A0A4U9USM0
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All DBs
Position
1:1984600..1985901
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AA seq
433 aa
AA seq
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MDIQSLYQIYKQYPNITTDTRKIEKDSIFFALKGANFNGNTFAAQALEIGAKYVVIDEEI
YKAGEEYILVNDVLQALQELAKHHRRQLDIPVIGVTGTNGKTTTKELLYSVVSQKYKTYA
TKGNLNNHIGVPLTVLAIDESVEIAIIEMGANHLKEIAFLCDIAQPTHGLISNVGKAHLE
GFGSFEGVKKTKGELYDWLQDHEGILFLQADNPHLKEMAAARKISKTITYGFSEDNDVIG
KLLKATPLLQIAWKRKGEERVYEVDTQLTGSYNTENFLAAIAVGLHFAISAEAINKGIEG
YAPTNNRSQIMNTAYNTVICDYYNANATSMAAALDNIRVIEAQKKAIILGDMFELGAESF
AEHRKLVEQVKTVDADRKIFVGKAFFEHCHEGAEFYETTDQARAALETNPVKGATVLLKA
SRGMAFENLIGVL
NT seq
1302 nt
NT seq
+upstream
nt +downstream
nt
atggacatccaatctttatatcagatttataaacagtatccaaatattacgacagataca
cgtaagatcgaaaaggatagtatattttttgcgctcaaaggagccaatttcaatggaaat
acctttgcagcacaagcgttagaaatcggagcgaagtatgttgtcattgatgaagaaatt
tataaggctggggaagaatatattttggtgaatgatgtgctgcaagccttacaggaactg
gcgaagcaccatcgtcggcagttagatattccggtcatcggcgttacgggaacaaacgga
aagacaacaaccaaggagttattgtattccgttgtttctcaaaaatataagacgtacgcg
acaaaaggcaatctcaataatcatatcggtgtacccttaacggtattggctatcgatgag
tcggttgaaattgccattatagaaatgggggccaaccatctgaaagagattgctttttta
tgtgatattgcacagccgacacatgggctgatctccaatgtgggcaaagcacatttagaa
ggctttggatcgtttgaaggagtaaaaaaaacaaagggtgaattgtacgattggctgcag
gatcatgaaggtatattgttcctacaggcagacaatcctcatcttaaggaaatggcggcc
gcacgcaaaataagcaagactatcacttatggattctctgaagacaacgatgtgatcggc
aagcttctgaaagcgacgccactgttacagattgcatggaagcgaaaaggcgaggagcga
gtttacgaagtcgatacacagttgaccggttcttataatactgaaaactttttggcagcg
atagccgtaggcctgcattttgcgatttctgccgaagcgatcaataagggtattgaaggc
tatgcgcccaccaacaatcgttcacaaatcatgaacacggcttataatacagtcatttgt
gattattataatgccaatgcgaccagcatggctgctgctttagataatatccgggtgata
gaagcacagaaaaaggctattatcttaggtgacatgtttgaattgggggctgagtctttt
gcggaacaccgcaaacttgtcgagcaagtaaaaacggtagatgctgatcgcaaaatcttt
gttgggaaagcatttttcgagcactgtcacgaaggagctgagttctatgaaacgacggat
caggcaagggcagcattggagacgaaccccgtcaaaggagctaccgtattattgaaagcc
tcccgtggtatggcattcgaaaatttgattggtgtcttatag
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