Streptomyces thermocarboxydus: AY578_18420
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Entry
AY578_18420 CDS
T11957
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
sthc Streptomyces thermocarboxydus
Pathway
sthc00860
Porphyrin metabolism
sthc01100
Metabolic pathways
sthc01110
Biosynthesis of secondary metabolites
sthc01120
Microbial metabolism in diverse environments
sthc01240
Biosynthesis of cofactors
Module
sthc_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
Brite
KEGG Orthology (KO) [BR:
sthc00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
AY578_18420
Enzymes [BR:
sthc01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
AY578_18420
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
AY578_18420
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Other DBs
NCBI-ProteinID:
UVT11068
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Position
4013816..4015522
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AA seq
568 aa
AA seq
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MSPTTLPAPPEQGHVTFLGAGPGDPGLLTLRAVEALANADVLVAEHDVLDVVRTHARQGV
AEVHTDADTSASSTPGTGTPQLTVVDGASTTAGVPANRDAAHLVMEAARGGKRVVRAVSG
DPGLDAYAAEEMLACASAGVPFEVVPGVATAVGVPAYAGVPLRDAQGTDVRFVDARTASD
RCWTEVGASDGTVVVSTTLDSVAAAAGELVSAGRKPDTPLTVTVAGTTTRQRTWTATLGT
IAQTLKQAKVLPSPEGGRPVIAVVGERSAAAQRDRLAWFESKPLFGWKVLVPRTKEQAAS
LSDQLRSYGAVPHEVPTIAVEPPRTPQQMERAVKGLVTGRYEWIAFTSVNAVKAVREKFE
EYGLDARAFAGIKVAAVGEQTAKALIAFGVKPDLVPSGEQSAAGLLEDWPPYDPVFDPID
RVFLPRADIATETLVAGLIELGWEVDDVTAYRTVRASPPPAETREAIKGGGFDAVLFTSS
STVRNLVGIAGKPHNVTVIACIGPATAKTAEEHGLRVDVMAPEPSVHKLAEALADFGARR
RLAALEAGDPVTRPSERRPGARRRRSTT
NT seq
1707 nt
NT seq
+upstream
nt +downstream
nt
ttgagccccaccactcttcccgcccctccggaacaagggcacgtcaccttcctcggtgcc
ggacccggggatccgggactgctgaccctgcgcgccgtggaggccctggcgaacgcggac
gtcctcgtcgccgagcacgacgtgctcgatgtcgtacggacgcacgccaggcagggcgtc
gccgaggtgcacacggacgcggacacgtctgcgtcgtccacgccgggcacgggcacgccc
cagctgacggtcgttgacggcgcgtcaacaaccgccggtgtccccgcgaatagggatgcc
gcacatcttgtcatggaggccgcgcggggcggcaagcgggtcgtccgtgcggtgtccggc
gaccccgggctcgatgcgtacgccgccgaggagatgctggcgtgcgcctcggccggggtg
ccgttcgaggtcgtccccggtgtcgccaccgcggtcggcgtgcccgcgtacgccggtgtg
ccgctgcgtgacgcgcagggcaccgacgtgcggttcgtcgacgcgcgcacggcgtccgac
cggtgctggaccgaggtcggcgcctccgacggcacggtggtcgtgtccaccacgctggac
tcggtggccgccgccgcgggcgaactggtgtccgccggacgtaagcccgacaccccgctg
acggtgaccgtcgccggcaccacgacccggcagcgcacctggacggcgacgctcggcacg
atcgcgcagacgctgaagcaggcgaaggtgctgccctcccctgagggcggccgcccggtg
atagccgtggtcggtgagcgttccgccgccgcccagcgggaccggctggcgtggttcgag
tccaagccgctgttcggctggaaggtgctcgtgccgcgcaccaaggagcaggcggcgtcg
ctctccgaccagctgcggtcctacggggccgtgccgcacgaggtgccgaccatcgcggtc
gagccgccgcgcacgccccagcagatggagcgcgcggtcaagggcctggtcaccggccgc
tacgagtggatcgcgttcacgtcggtcaacgcggtcaaggcggtgcgcgagaagttcgag
gagtacgggctcgacgcccgcgccttcgccgggatcaaggtcgcggcggtgggcgagcag
accgcgaaggcgctgatcgccttcggcgtgaagccggacctggtgccgagcggcgagcag
tcggccgcgggcctgctggaggactggccgccgtacgacccggtcttcgacccgatcgac
cgtgtcttcctgccgcgcgccgacatcgccaccgagacgctggtcgcggggctgatcgag
ctgggctgggaggtcgacgacgtcaccgcctaccggacggtgcgcgcgtcgccgccgccg
gcggaaacccgcgaggcgatcaagggcggcggcttcgacgcggtgctgttcacctcgtcg
tcgacggtccggaacctggtcggcatcgccggcaagccgcacaacgtgacggtgatcgcg
tgtatcggcccggccacggcgaagacggccgaggagcacgggctgcgggtggacgtgatg
gctcccgagccgtcggtccacaagctggcggaggccctcgcggacttcggcgcgcggcgc
cggctggccgcgctggaggcgggtgacccggtcacccggcccagcgagcggcggccgggg
gcgcggagacgtcgttccacgacgtga
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