Streptomyces sp. HP-A2021: MQE23_06660
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Entry
MQE23_06660 CDS
T11535
Name
(GenBank) NADP-dependent isocitrate dehydrogenase
KO
K00031
isocitrate dehydrogenase [EC:
1.1.1.42
]
Organism
sthp Streptomyces sp. HP-A2021
Pathway
sthp00020
Citrate cycle (TCA cycle)
sthp00480
Glutathione metabolism
sthp00720
Other carbon fixation pathways
sthp01100
Metabolic pathways
sthp01110
Biosynthesis of secondary metabolites
sthp01120
Microbial metabolism in diverse environments
sthp01200
Carbon metabolism
sthp01210
2-Oxocarboxylic acid metabolism
sthp01230
Biosynthesis of amino acids
sthp04146
Peroxisome
Module
sthp_M00009
Citrate cycle (TCA cycle, Krebs cycle)
sthp_M00010
Citrate cycle, first carbon oxidation, oxaloacetate => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:
sthp00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00020 Citrate cycle (TCA cycle)
MQE23_06660
09102 Energy metabolism
00720 Other carbon fixation pathways
MQE23_06660
09106 Metabolism of other amino acids
00480 Glutathione metabolism
MQE23_06660
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
MQE23_06660
Enzymes [BR:
sthp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.42 isocitrate dehydrogenase (NADP+)
MQE23_06660
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GFIT
Motif
Pfam:
IDH
Motif
Other DBs
NCBI-ProteinID:
UOB08752
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Position
1472294..1474513
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AA seq
739 aa
AA seq
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MTDSTIIYTHTDEAPALATYSFLPVVQAYASQAGVAVETRDISLAGRIVALFPEYLTEDQ
RIPDALAELGRLAKTPAANIIKLPNISASIPQLKAAIAELQGQGYALPDYPDDPKTDEER
EIRARYDKVKGSAVNPVLREGNSDRRAPASVKNYAKSHPHRMGAWSADSRTSVATMGQND
FRSTEKSVVIAEDGALRIELVGDDGTTTVLRESVPVQKGEVVDASVMRVAALREFLTAQV
AEAKAQGVLFSVHLKATMMKVSDPIVFGHVVRAFFPKTFAKYGDKLAAAGLTPNDGLGGI
WKGLDALPEGAEIKASFDAELTEGPELAMVDSDKGITNLHVPSDVIIDASMPAMIRSSGH
MWGADGQEHDALAVIPDSSYAGVYQAVIEDCKANGAFDPSTMGTVPNVGLMAQKAEEYGS
HDKTFEIATTGTVRLVDQNGTALIEQTVSAGDIFRACQTKDAPIRDWVKLAVTRARATGD
PAVFWLDETRAHDANLIAKVKAYLPEHDTEGLDIRILNPVEATKLSVERIRRGENTISVT
GNVLRDYLTDLFPILELGTSAKMLSVVPLMAGGGLFETGAGGSAPKHVQQLVKENYLRWD
SLGEFFALVPSLEQYAKVTGNARAQVLADTLDRATATFLNEDKSPTRRVGGIDNRGSHFY
LSLYWAQELAQQSDDADLAKAFAPIAETLAANEQKIIDELAAVQGKPADIGGYYQPDPAK
AAEVMRPSATWNEALASLS
NT seq
2220 nt
NT seq
+upstream
nt +downstream
nt
gtgactgactcgaccatcatctatacgcacactgacgaggccccggccctggcaacgtat
tccttcctgccggtggtccaggcgtacgcctcgcaggcgggtgtcgccgtcgagacccgc
gacatctcgctggccgggcgcatcgtcgccctgttcccggagtacctcaccgaggaccag
cgcatcccggacgccctcgcggagctcggccggctggccaagacgcccgccgccaacatc
atcaagctgccgaacatctcggcgtcgatcccgcagctcaaggccgccatcgccgagctc
cagggccagggctacgcgctgccggactacccggacgacccgaagaccgacgaggagcgc
gagatccgcgcccgctacgacaaggtcaagggctccgccgtgaacccggtcctgcgtgag
ggcaactcggaccgccgggcccccgcctcggtcaagaactacgccaagtcccacccgcac
cgcatgggcgcctggtccgccgactccaggacgagcgtggcgaccatgggccagaacgac
ttccgctccaccgagaagtccgtggtgatcgccgaggacggcgcgctgcgcatcgagctc
gtcggcgacgacggcaccaccaccgtgctgcgcgagtccgtacccgtccagaagggcgag
gtcgtcgacgcctccgtgatgcgggtcgccgcgctgcgcgagttcctgacggcgcaggtc
gccgaggccaaggcccagggcgtgctgttctcggtgcacctgaaggcgacgatgatgaag
gtctccgacccgatcgtcttcggccacgtggtgcgcgccttcttcccgaagacgttcgcg
aagtacggcgacaagctcgccgcggccggcctgaccccgaacgacggtctgggcggcatc
tggaagggcctggacgccctgcccgagggtgccgagatcaaggcctccttcgacgccgag
ctcaccgagggcccggagctggcgatggtcgactccgacaagggcatcaccaacctgcac
gtgccctccgacgtcatcatcgacgcctccatgccggccatgatccgcagctccggccac
atgtggggcgcggacgggcaggagcacgacgccctggcggtcatcccggactcctcctac
gcgggcgtctaccaggccgtgatcgaggactgcaaggccaacggcgccttcgacccgtcc
accatgggcacggtgccgaacgtcggcctcatggcccagaaggccgaggagtacggcagc
cacgacaagaccttcgagatcgccaccacgggcacggtccgcctggtcgaccagaacggc
accgcgctcatcgagcagaccgtctcggccggcgacatcttccgcgcctgccagaccaag
gacgcgccgatccgggactgggtgaagctggccgtcacccgcgcccgcgccaccggcgac
ccggcggtgttctggctggacgagacccgcgcgcacgacgccaacctgatcgccaaggtc
aaggcgtacctgccggagcacgacaccgagggcctggacatccggatcctgaacccggtc
gaggccacgaagctgtcggtggagcgcatccgccgcggcgagaacaccatctcggtgacc
ggcaacgtgctgcgcgactacctgaccgacctgttcccgatcctggagctgggcaccagc
gccaagatgctgtcggtcgtcccgctgatggcgggcggcggcctgttcgagacgggtgcg
ggcggctcggcgccgaagcacgtgcagcagctggtcaaggagaactacctgcgctgggac
tccctgggtgagttcttcgccctcgtgccgtccctcgagcagtacgcgaaggtgacgggc
aacgcccgtgcccaggtcctcgccgacaccctcgaccgcgccacggcgaccttcctcaac
gaggacaagtcgccgacccggcgcgtcggcggcatcgacaaccgcggcagccacttctac
ctgtccctgtactgggcgcaggagctggcccagcagagcgacgacgcggacctggcgaag
gcgttcgcgccgatcgccgagacgctcgccgccaacgagcagaagatcatcgacgagctg
gccgccgtccagggcaagccggccgacatcggcggctactaccagcccgacccggcgaag
gccgccgaggtcatgcgcccgtccgccacgtggaacgaggcgctggcgtccctgagctga
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