Streptomyces sp. ICC4: DRB89_17260
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Entry
DRB89_17260 CDS
T10587
Name
(GenBank) phosphoribosylformylglycinamidine synthase subunit PurL
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
stic Streptomyces sp. ICC4
Pathway
stic00230
Purine metabolism
stic01100
Metabolic pathways
stic01110
Biosynthesis of secondary metabolites
Module
stic_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
stic00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
DRB89_17260
Enzymes [BR:
stic01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
DRB89_17260
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
AWZ06079
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Position
3701152..3703401
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AA seq
749 aa
AA seq
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MSLDTVKNATETPDASQPWKELGLKEDEYARIKEILGRRPTGAELAMYSVMWSEHCSYKS
SKVHLKQFGEKVPPNDAMLVGIGENAGVVDVGQGYAVTFKVESHNHPSYIEPYQGAATGI
GGIVRDILAMGARPIAVVDPLRFGAADHPDTKRVLPGVVAGIGGYGNCLGLPNIGGEVVF
DACYQGNPLVNAGCIGVMKHEDIHLAKASGPGNKVILYGARTGGDGIGGVSVLASETFDD
TKPTKRPAVQVGDPFQEKLLIECTLEIFKEKLVAGIQDLGGAGLSCATSELASAGSGGMR
VELDTVPLRDATLSPEEILMSESQERMCAIVEPQYVDRFMEICEKWDVIATVIGEVTEGE
QLEIFWHGELIVDVPPGTVAHEGPTYHRPYARPSWQDALQADDAGKLPRPQTSEELRAQV
LALVSSPNQASKSWITDQYDRFVQGNTVLSQPEDAGMVRIDEETNLGVAMATDGNGRFAK
LDPYTGAQLALAEAYRNVAATGAKPLAISDCLNFGSPEDPDVMWQFAEATRGLADGCFEL
GTPVTGGNVSLYNQTGDIAIHPTPVVAVLGVIDDVNRRTPMAFAEAGQLLYLLGDTAEEF
GGSAWSEVVHQHLGGMPPKVDLGREKLLGEILISASRDGMIDAAHDLSDGGVIQALTESC
LRGGNGARIVVPEALDAFTFLFSESAGRAIVAVPRSEELRFTDMCGARGLPAARIGVVDG
EEIEIQGEFTLPLAELRTAHEGTIPGLLA
NT seq
2250 nt
NT seq
+upstream
nt +downstream
nt
atgagcctcgacaccgtcaagaacgccaccgagaccccggacgcctcccagccctggaag
gaactcggcctcaaggaggacgagtacgcccggatcaaggagatcctcggccgccgtccc
accggcgccgagctcgccatgtactcggtcatgtggtccgagcactgctcgtacaagagc
agcaaggtccacctgaagcagttcggcgagaaggtcccgccgaacgacgccatgctcgtc
ggcatcggcgagaacgccggcgtcgtcgatgtgggccagggctacgcggtcaccttcaag
gtggagtcgcacaaccacccgagctacatcgagccctaccagggcgcggccaccggcatc
ggcggcatcgtccgcgacatcctcgccatgggcgcccgcccgatcgccgtcgtcgacccg
ctgcgcttcggcgcggccgaccaccccgacaccaagcgcgtcctgccgggcgtcgtcgcg
ggcatcggcggctacggcaactgcctcggcctgccgaacatcggcggcgaggtcgtcttc
gacgcctgctaccagggcaacccgctcgtcaacgccggctgcatcggcgtgatgaagcac
gaggacatccacctcgccaaggcctccggccccggcaacaaggtcatcctctacggcgcc
cgcacgggcggcgacggcatcggcggcgtgtccgtgctggcctcggagaccttcgacgac
acgaagccgaccaagcgtccggcggtccaggtcggcgaccccttccaggagaagctcctc
atcgagtgcaccctggagatcttcaaggagaagctggtcgcgggcatccaggacctcggc
ggcgccgggctctcctgcgccacgtccgagctggcctccgccggttccggcggcatgcgc
gtcgagctggacaccgtcccgctgcgcgatgcgacgctctcgcccgaggaaatcctcatg
agcgagtcgcaggagcgcatgtgcgcgatcgtcgagccgcagtacgtcgaccgcttcatg
gagatctgcgagaagtgggacgtcatcgccaccgtcatcggtgaggtgaccgagggcgag
cagctggagatcttctggcacggcgagctcatcgtggacgtgcccccgggcaccgtcgcc
cacgagggccccacctaccaccgcccctacgcgcgcccctcctggcaggacgcgctgcag
gcggacgacgcgggcaagctgccgcggccgcagacctccgaggagctgcgcgcgcaggtc
ctggccctggtctcgtcgccgaaccaggcctcgaagtcctggatcaccgaccagtacgac
cgcttcgtgcagggcaacacggtgctctcgcagcccgaggacgccggcatggtccgcatc
gacgaggagaccaacctcggcgtcgcgatggccaccgacggcaacggccgcttcgccaag
ctcgacccgtacacgggcgcgcagctggcgctggccgaggcgtaccgcaacgtcgccgcg
accggcgcgaagccgctggccatctccgactgcctgaacttcggctcccccgaggacccg
gacgtcatgtggcagttcgccgaggccacccgtggtctcgccgacggctgcttcgagctg
ggcaccccggtgaccggcggcaacgtctcgctctacaaccagaccggtgacatcgcgatc
cacccgaccccggtcgtggcggtcctcggtgtgatcgacgacgtcaaccgccgcacgccg
atggcgttcgcggaggccggccagctgctgtacctgctcggcgacaccgccgaggagttc
ggcggctccgcctggtccgaggtcgtccaccagcacctgggcggcatgccgcccaaggtg
gacctgggccgcgagaagctgctcggcgagatcctgatctcggcctcgcgcgacggcatg
atcgacgccgcgcacgacctgtccgacggcggcgtgatccaggcgctcaccgagtcctgc
ctgcgcggcggcaacggtgcgcggatcgtggtgcccgaggccctggacgccttcaccttc
ctcttctccgagtcggcgggccgggccatcgtggccgtcccgcgcagcgaggagctccgc
ttcaccgacatgtgcggtgcgcggggcctcccggcggcccggatcggtgtggtggacggc
gaggagatcgagatccagggcgagttcacgctccccctggccgagctccgcaccgcccac
gaggggacgatcccggggctgctggcctga
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