Streptomyces sp. ICC4: DRB89_18080
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Entry
DRB89_18080 CDS
T10587
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
stic Streptomyces sp. ICC4
Pathway
stic00280
Valine, leucine and isoleucine degradation
stic00640
Propanoate metabolism
stic00785
Lipoic acid metabolism
stic01100
Metabolic pathways
stic01110
Biosynthesis of secondary metabolites
stic01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stic00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
DRB89_18080 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
DRB89_18080 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
DRB89_18080 (pdhA)
Enzymes [BR:
stic01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
DRB89_18080 (pdhA)
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Ortholog
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
AWZ06218
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All DBs
Position
3905290..3906498
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AA seq
402 aa
AA seq
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MTVESTAARKPRRSSGTKRPAGAASAAKPAAATAKTHDAEPQLVQLLTPEGERREVADHP
DIAEFAPYVADITTEDLRGLYRDMVMTRRFDGEATALQRQGELGLWASLLGQEAAQIGSG
RALRDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPTTNNFHLYTIVIGSQTL
HATGYAMGVAKDGADSAVIAYFGDGASSQGDVAEAFTFSAVYNSPVVFFCQNNQWAISEP
TERQMRVPLYQRAQGFGFPGVRVDGNDVLACLAVTRWALERARRGEGPTLVEAFTYRMGA
HTTSDDPTKYRRDEETAAWEAKDPILRLKAHLLATGGADEAYFEQLEVESEALGKRVREV
VRSMPDPDTMAIFENVYADGHALVDEERAQFAAYIASFEGGE
NT seq
1209 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggagagcactgccgcgcgcaagccgcgacgcagcagcggcaccaagcggccg
gccggcgcggcaagcgccgccaagcccgccgctgccaccgcgaagacgcatgacgccgag
ccccagctcgtacagctgctgacgcccgagggcgaacggcgcgaggtcgcggaccatccc
gacatcgccgaattcgcaccctacgtcgccgacatcaccaccgaggacctgcgcggtctc
taccgcgacatggtcatgacccgccgcttcgacggcgaggcgaccgccctgcagcgccag
ggcgagctgggcctgtgggcctcgctcctgggccaggaggcggcgcagatcggctccggc
cgggcgctgcgcgacgacgactacgtcttcccgacctaccgcgagcacggcgtggcctgg
tgccgcggggtcgacccgacgaacctcctcggcatgttccgcggtgtgaaccacggtggc
tgggacccgaccaccaacaacttccacctgtacacgatcgtcatcggctcccagacgctg
cacgcgaccgggtacgcgatgggcgtggccaaggacggcgccgactcggccgtcatcgcc
tacttcggcgacggcgcgtccagccagggcgacgtcgcggaagccttcaccttctcggcc
gtctacaactcgcccgtggtgttcttctgccagaacaaccagtgggcgatctccgagccc
accgagcgccagatgcgcgtaccgctctaccagcgcgcacagggcttcggcttcccgggc
gtccgcgtggacggcaacgacgtactggcctgcctcgcggtgacgcggtgggcgctggag
cgggcccgccggggcgaggggcccacgctggtcgaggcgttcacgtaccgcatgggcgcg
cacaccacctccgacgacccgacgaagtaccggcgcgacgaggagacggcggcctgggag
gccaaggacccgatcctgcgcctgaaggcccacctgctggccaccggaggcgccgacgag
gcgtacttcgagcagctggaggtggagagcgaggcgctgggcaagcgggtgcgcgaggtc
gtgcgctcgatgcccgaccccgacaccatggcgatcttcgagaacgtctacgcggacggg
cacgcgctcgtcgacgaggagcgcgcgcagttcgccgcttacatcgcgtccttcgaaggc
ggggagtga
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