Streptomyces sp. ID38640: G7Z12_18655
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Entry
G7Z12_18655 CDS
T11207
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
stid Streptomyces sp. ID38640
Pathway
stid00280
Valine, leucine and isoleucine degradation
stid00640
Propanoate metabolism
stid00785
Lipoic acid metabolism
stid01100
Metabolic pathways
stid01110
Biosynthesis of secondary metabolites
stid01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
stid00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
G7Z12_18655 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
G7Z12_18655 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
G7Z12_18655 (pdhA)
Enzymes [BR:
stid01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
G7Z12_18655 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
QIK07762
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Position
4387891..4389108
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AA seq
405 aa
AA seq
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MTVEGTAQRKNARGSTKRTTAKKATSAKKASPAKARNSGRPDQAEQDQLVQLLTPEGKRV
EHPDFSIDLSAEELRGLYRDMVLTRKFDAEATTLQRQGELGLWASLLGQEAAQIGSGRAL
RDDDYVFPTYREHGVAWCRGVDPTNLLGMFRGVNHGGWDPNTNNFHLYTIVIGSQTLHAT
GYAMGVQKDGADSAVIAYFGDGASSQGDVAESFTFSAVYNAPVVFFCQNNQWAISEPTEK
QTRVPLYQRARGFGFPGVRVDGNDVLACLAVTKAALERARTGQGPMLIEAFTYRMGAHTT
SDDPTKYRADEERAAWEAKDPILRLRTYLEAEGIVDEAYLASIDEESEALGKRVRDAVRA
MPDPDTMAIFENVYADGHALVDEERAQFAAYQASFADADLVAEGN
NT seq
1218 nt
NT seq
+upstream
nt +downstream
nt
gtgaccgtggaaggcactgcgcagcggaaaaacgcccgcggcagcaccaagcgcaccacc
gccaaaaaggcgacgtcggcgaagaaggcgtccccggccaaggcccggaactccggccgg
cccgaccaggcggagcaggatcagctcgtacaactgctgacgcccgaagggaagcgggtc
gagcacccggatttctcgatcgatctttccgccgaagaactgcgcgggctctaccgcgac
atggtgctgacgcggaagttcgatgccgaggcgaccaccctccagcgccagggcgaactg
ggcctgtgggcctcgctgctgggccaggaagccgcccagatcggctccggccgcgcgctg
cgcgacgacgactacgtcttcccgacctaccgcgagcacggtgtggcttggtgccgcgga
gtcgacccgacgaacctgctgggcatgttccgcggtgtcaatcacggcggctgggatccc
aacaccaacaacttccacctctacaccatcgtcatcggctcgcagactctgcatgcgacc
ggctatgcgatgggtgtgcagaaggacggcgcggattccgcggtcatcgcctatttcggt
gacggtgcttccagccagggcgatgtcgcggaatccttcaccttctccgcggtctacaac
gccccggtcgtgttcttctgccagaacaaccaatgggcgatttccgaacccactgagaag
cagacccgggtgccgctctaccagcgcgcccgtggcttcggattccccggcgtacgggtc
gacggcaatgacgtactggcctgtctggcggtgaccaaggcggcactggagcgggcgcgc
accggccagggcccgatgctcatcgaggcgttcacctaccgcatgggcgcgcacaccacc
tccgacgacccgacgaagtaccgggcggacgaggagcgggcggcctgggaggccaaggac
ccgatcctgcggctgcggacgtacctggaggccgagggcatcgtcgacgaggcctatctc
gcctcgatcgacgaggagagcgaggccctgggcaagcgggtccgcgatgccgtacgcgcc
atgcccgacccggacaccatggcgatcttcgagaatgtctatgccgacgggcatgcgctc
gtcgatgaggagcgcgcgcagttcgccgcgtaccaggcgtcgttcgccgacgccgatctc
gtcgcggaggggaactga
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